6HF0
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![BU of 6hf0 by Molmil](/molmil-images/mine/6hf0) | M. tuberculosis DprE1 covalently bound to a nitrobenzoxacinone. | 分子名称: | 2-[(2~{S},6~{R})-2,6-dimethylpiperidin-1-yl]-8-nitro-6-(trifluoromethyl)-1,3-benzoxazin-4-one, Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Futterer, K, Batt, S.M, Besra, G.S. | 登録日 | 2018-08-21 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.384 Å) | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Sci Rep, 8, 2018
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6HFV
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![BU of 6hfv by Molmil](/molmil-images/mine/6hfv) | Mycobacterium tuberculosis DprE1 in complex with CMP2 | 分子名称: | 8-(oxidanylamino)-2-piperidin-1-yl-6-(trifluoromethyl)-1,3-benzothiazin-4-one, Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Chung, C. | 登録日 | 2018-08-21 | 公開日 | 2018-09-19 | 最終更新日 | 2019-08-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Sci Rep, 8, 2018
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6HFW
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![BU of 6hfw by Molmil](/molmil-images/mine/6hfw) | Mycobacterium tuberculosis DprE1 in complex with CMP1 | 分子名称: | 8-(oxidanylamino)-2-piperidin-1-yl-6-(trifluoromethyl)-1,3-benzothiazin-4-one, Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Chung, C. | 登録日 | 2018-08-21 | 公開日 | 2018-09-19 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Sci Rep, 8, 2018
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6HF3
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![BU of 6hf3 by Molmil](/molmil-images/mine/6hf3) | M tuberculosis DprE1 in complex with a covalently bound nitrobenzothiazinone | 分子名称: | 2-(4-(cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one, bound form, Decaprenylphosphoryl-beta-D-ribose oxidase, ... | 著者 | Futterer, K, Batt, S.M, Besra, G.S. | 登録日 | 2018-08-21 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Sci Rep, 8, 2018
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6HEZ
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![BU of 6hez by Molmil](/molmil-images/mine/6hez) | M tuberculosis DprE1 in complex with BTZ043 | 分子名称: | 8-(hydroxyamino)-2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one, Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Futterer, K, Batt, S.M, Besra, G.S. | 登録日 | 2018-08-21 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Sci Rep, 8, 2018
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2WYQ
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![BU of 2wyq by Molmil](/molmil-images/mine/2wyq) | |
2P4B
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![BU of 2p4b by Molmil](/molmil-images/mine/2p4b) | Crystal structure of E.coli RseB | 分子名称: | Sigma-E factor regulatory protein rseB, octyl beta-D-glucopyranoside | 著者 | Kim, D.Y, Kim, K.K. | 登録日 | 2007-03-12 | 公開日 | 2007-05-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of RseB and a model of its binding mode to RseA Proc.Natl.Acad.Sci.Usa, 104, 2007
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3DNE
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![BU of 3dne by Molmil](/molmil-images/mine/3dne) | |
3DND
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3CCN
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![BU of 3ccn by Molmil](/molmil-images/mine/3ccn) | X-ray structure of c-Met with triazolopyridazine inhibitor. | 分子名称: | 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol, Hepatocyte growth factor receptor | 著者 | Abrecht, B.K, Harmange, J.-C, Bauer, D, Dussault, I, long, A, Bellon, S.F. | 登録日 | 2008-02-26 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
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3CD8
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![BU of 3cd8 by Molmil](/molmil-images/mine/3cd8) | X-ray Structure of c-Met with triazolopyridazine Inhibitor. | 分子名称: | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline, Hepatocyte growth factor receptor | 著者 | Bellon, S.F, Albrecht, B.K, Harmange, J.-C, Bauer, D, Choquette, D, Dussault, I. | 登録日 | 2008-02-26 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
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