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2VP3
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DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1996-12-16
公開日1997-09-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4, 1997
3C0W
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I-SceI in complex with a bottom nicked DNA substrate
分子名称: CALCIUM ION, DNA (5'-D(*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DGP*DTP*DAP*DAP*DTP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DT)-3'), ...
著者Moure, C.M, Gimble, F.S, Quiocho, F.A.
登録日2008-01-21
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
3C0X
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I-SceI in complex with a top nicked DNA substrate
分子名称: CALCIUM ION, DNA (5'-D(*DC*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DA)-3'), DNA (5'-D(*DG*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DCP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DT)-3'), ...
著者Moure, C.M, Gimble, F.S, Quiocho, F.A.
登録日2008-01-21
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
1GLG
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CRYSTALLOGRAPHIC ANALYSIS OF THE EPIMERIC AND ANOMERIC SPECIFICITY OF THE PERIPLASMIC TRANSPORT(SLASH)CHEMOTACTIC PROTEIN RECEPTOR FOR D-GLUCOSE AND D-GALACTOSE
分子名称: CALCIUM ION, GALACTOSE/GLUCOSE-BINDING PROTEIN, beta-D-galactopyranose
著者Vyas, M.N, Vyas, N.K, Quiocho, F.A.
登録日1993-12-27
公開日1994-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic analysis of the epimeric and anomeric specificity of the periplasmic transport/chemosensory protein receptor for D-glucose and D-galactose.
Biochemistry, 33, 1994
2F3Z
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Calmodulin/IQ-AA domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel alpha-1C subunit
著者Fallon, J.L, Quiocho, F.A.
登録日2005-11-22
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel.
Structure, 13, 2005
2F3Y
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Calmodulin/IQ domain complex
分子名称: CALCIUM ION, Calmodulin, MAGNESIUM ION, ...
著者Fallon, J.L, Quiocho, F.A.
登録日2005-11-22
公開日2005-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel.
Structure, 13, 2005
1M7I
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CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE
分子名称: alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-alpha-L-rhamnopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-methyl 6-deoxy-alpha-L-rhamnopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-19
公開日2003-07-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
1MAR
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REFINED 1.8 ANGSTROMS STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH THE POTENT INHIBITOR ZOPOLRESTAT
分子名称: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wilson, D.K, Quiocho, F.A.
登録日1993-07-20
公開日1995-07-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat.
Proc.Natl.Acad.Sci.USA, 90, 1993
3RRK
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Crystal structure of the cytoplasmic N-terminal domain of subunit I, homolog of subunit a, of V-ATPase
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, V-type ATPase 116 kDa subunit
著者Srinivasan, S, Vyas, N.K, Baker, M.L, Quiocho, F.A.
登録日2011-04-29
公開日2011-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of the cytoplasmic N-terminal domain of subunit I, a homolog of subunit a, of V-ATPase.
J.Mol.Biol., 412, 2011
4W9N
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Enoyl-acyl carrier protein-reductase domain from human fatty acid synthase complexed with triclosan
分子名称: CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase, IMIDAZOLE, ...
著者Sippel, K.H, Vyas, N.K, Sankaran, B, Quiocho, F.A.
登録日2014-08-27
公開日2014-10-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition.
J.Biol.Chem., 289, 2014
2LIV
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BU of 2liv by Molmil
PERIPLASMIC BINDING PROTEIN STRUCTURE AND FUNCTION. REFINED X-RAY STRUCTURES OF THE LEUCINE/ISOLEUCINE/VALINE-BINDING PROTEIN AND ITS COMPLEX WITH LEUCINE
分子名称: LEUCINE
著者Sack, J.S, Saper, M.A, Quiocho, F.A.
登録日1989-04-10
公開日1989-07-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Periplasmic binding protein structure and function. Refined X-ray structures of the leucine/isoleucine/valine-binding protein and its complex with leucine.
J.Mol.Biol., 206, 1989
1SBP
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1.7 ANGSTROMS REFINED STRUCTURE OF SULFATE-BINDING PROTEIN INVOLVED IN ACTIVE TRANSPORT AND NOVEL MODE OF SULFATE BINDING
分子名称: SULFATE ION, SULFATE-BINDING PROTEIN
著者Sack, J.S, Quiocho, F.A.
登録日1993-07-19
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dominant role of local dipoles in stabilizing uncompensated charges on a sulfate sequestered in a periplasmic active transport protein.
Protein Sci., 2, 1993
1IXI
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PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 56 REPLACED BY ASN COMPLEX WITH MONOBASIC PHOSPHATE ION
分子名称: DIHYDROGENPHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Quiocho, F.A.
登録日1996-10-17
公開日1997-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
Nat.Struct.Biol., 4, 1997
1IXG
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PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE
分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Luecke, H, Quiocho, F.A.
登録日1996-08-01
公開日1998-02-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
Nat.Struct.Biol., 4, 1997
1IXH
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PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE
分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Luecke, H, Quiocho, F.A.
登録日1996-08-01
公開日1998-02-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
Nat.Struct.Biol., 4, 1997
1UIO
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ADENOSINE DEAMINASE (HIS 238 ALA MUTANT)
分子名称: 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE, ADENOSINE DEAMINASE, ZINC ION
著者Wilson, D.K, Quiocho, F.A.
登録日1996-08-30
公開日1997-06-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.
Biochemistry, 35, 1996
1UIP
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ADENOSINE DEAMINASE (HIS 238 GLU MUTANT)
分子名称: ADENOSINE DEAMINASE, PURINE RIBOSIDE, ZINC ION
著者Wilson, D.K, Quiocho, F.A.
登録日1996-08-30
公開日1997-06-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation.
Biochemistry, 35, 1996
1FKX
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MURINE ADENOSINE DEAMINASE (D296A)
分子名称: 6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE, ADENOSINE DEAMINASE, ZINC ION
著者Wilson, D.K, Quiocho, F.A.
登録日1996-02-29
公開日1996-08-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase.
Biochemistry, 35, 1996
1FKW
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MURINE ADENOSINE DEAMINASE (D295E)
分子名称: ADENOSINE DEAMINASE, PURINE RIBOSIDE, ZINC ION
著者Wilson, D.K, Quiocho, F.A.
登録日1996-02-29
公開日1996-08-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase.
Biochemistry, 35, 1996
2LBP
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STRUCTURE OF THE L-LEUCINE-BINDING PROTEIN REFINED AT 2.4 ANGSTROMS RESOLUTION AND COMPARISON WITH THE LEU(SLASH)ILE(SLASH)VAL-BINDING PROTEIN STRUCTURE
分子名称: LEUCINE-BINDING PROTEIN
著者Sack, J.S, Trakhanov, S.D, Tsigannik, I.H, Quiocho, F.A.
登録日1989-04-10
公開日1989-07-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the L-leucine-binding protein refined at 2.4 A resolution and comparison with the Leu/Ile/Val-binding protein structure.
J.Mol.Biol., 206, 1989
2PFD
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Anisotropically refined structure of FTCD
分子名称: Formimidoyltransferase-cyclodeaminase
著者Poon, B.K, Chen, X, Lu, M, Quiocho, F.A, Wang, Q, Ma, J.
登録日2007-04-04
公開日2007-04-24
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Anisotropically refined structure of FTCD
To be Published
3G43
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Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Fallon, J.L, Quiocho, F.A.
登録日2009-02-03
公開日2009-03-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins.
Proc.Natl.Acad.Sci.USA, 106, 2009
4CLN
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STRUCTURE OF A RECOMBINANT CALMODULIN FROM DROSOPHILA MELANOGASTER REFINED AT 2.2-ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, CALMODULIN
著者Taylor, D.A, Sack, J.S, Maune, J.F, Beckingham, K, Quiocho, F.A.
登録日1991-06-24
公開日1992-07-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a recombinant calmodulin from Drosophila melanogaster refined at 2.2-A resolution.
J.Biol.Chem., 266, 1991
1APB
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A PRO TO GLY MUTATION IN THE HINGE OF THE ARABINOSE-BINDING PROTEIN ENHANCES BINDING AND ALTERS SPECIFICITY: SUGAR-BINDING AND CRYSTALLOGRAPHIC STUDIES
分子名称: L-ARABINOSE-BINDING PROTEIN, alpha-D-fucopyranose, beta-D-fucopyranose
著者Vermersch, P.S, Tesmer, J.J.G, Quiocho, F.A.
登録日1991-11-15
公開日1992-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A Pro to Gly mutation in the hinge of the arabinose-binding protein enhances binding and alters specificity. Sugar-binding and crystallographic studies.
J.Biol.Chem., 265, 1990
4DCG
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VACCINIA METHYLTRANSFERASE VP39 MUTANT D182A COMPLEXED WITH M7G AND S-ADENOSYLHOMOCYSTEINE
分子名称: 7-METHYLGUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A.
登録日1998-07-13
公開日1999-07-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains.
Proc.Natl.Acad.Sci.USA, 96, 1999

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