3IHG
 
 | | Crystal structure of a ternary complex of aklavinone-11 hydroxylase with FAD and aklavinone | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, RdmE, SULFATE ION, ... | | 著者 | Lindqvist, Y, Koskiniemi, H, Jansson, A, Sandalova, T, Schneider, G. | | 登録日 | 2009-07-30 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis.
J.Mol.Biol., 393, 2009
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7OWB
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-hydroxylase CalMB | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-06-17 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7OY1
 | | DnrK mutant RTCR | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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4WXH
 | | Carminomycin-4-O-methyltransferase (DnrK) variant (298Ser insert) in complex with S-adenosyl-L-homocysteine (SAH) and aclacinomycin T | | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Carminomycin 4-O-methyltransferase DnrK, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Metsa-Ketela, M, Niiranen, L. | | 登録日 | 2014-11-13 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Divergent evolution of an atypical S-adenosyl-l-methionine-dependent monooxygenase involved in anthracycline biosynthesis.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4OSP
 | | The crystal structure of urdamycin C-6 ketoreductase domain UrdMred with bound NADP and rabelomycin | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxygenase-reductase, rabelomycin | | 著者 | Niiranen, L, Paananen, P, Patrikainen, P, Metsa-Ketela, M. | | 登録日 | 2014-02-13 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure-based engineering of angucyclinone 6-ketoreductases.
Chem.Biol., 21, 2014
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2F99
 | | Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity. | | 分子名称: | Aklanonic Acid methyl Ester Cyclase, AknH, SULFATE ION, ... | | 著者 | Kallio, P, Sultana, A, Neimi, J, Mantsala, P, Schneider, G. | | 登録日 | 2005-12-05 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
J.Mol.Biol., 357, 2006
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2F98
 | | Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity. | | 分子名称: | Aklanonic Acid methyl Ester Cyclase, AknH, METHYL 5,7-DIHYDROXY-2-METHYL-4,6,11-TRIOXO-3,4,6,11-TETRAHYDROTETRACENE-1-CARBOXYLATE, ... | | 著者 | Kallio, P, Sultana, A, Neimi, J, Mantsala, P, Schneider, G. | | 登録日 | 2005-12-05 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
J.Mol.Biol., 357, 2006
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4OSO
 | | The crystal structure of landomycin C-6 ketoreductase LanV with bound NADP and rabelomycin | | 分子名称: | DI(HYDROXYETHYL)ETHER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Reductase homolog, ... | | 著者 | Paananen, P, Niiranen, L, Patrikainen, P, Metsa-Ketela, M. | | 登録日 | 2014-02-13 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based engineering of angucyclinone 6-ketoreductases.
Chem.Biol., 21, 2014
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5EBI
 | | Crystal structure of a DNA-RNA chimera in complex with Ba2+ ions: a case of unusual multi-domain twinning | | 分子名称: | BARIUM ION, DNA/RNA (5'-D(*C)-R(P*G)-D(P*C)-R(P*G)-D(P*C)-R(P*G)-3') | | 著者 | Gilski, M, Drozdzal, P, Kierzek, R, Jaskolski, M. | | 登録日 | 2015-10-19 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Atomic resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba(2+) ions: a case of complicated multi-domain twinning.
Acta Crystallogr D Struct Biol, 72, 2016
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1SJW
 | | Structure of polyketide cyclase SnoaL | | 分子名称: | METHYL 5,7-DIHYDROXY-2-METHYL-4,6,11-TRIOXO-3,4,6,11-TETRAHYDROTETRACENE-1-CARBOXYLATE, nogalonic acid methyl ester cyclase | | 著者 | Sultana, A, Kallio, P, Jansson, A, Wang, J.S, Neimi, J, Mantsala, P, Schneider, G, Structural Proteomics in Europe (SPINE) | | 登録日 | 2004-03-04 | | 公開日 | 2004-04-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation.
Embo J., 23, 2004
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2GEY
 | | Crystal Structure of AclR a putative hydroxylase from Streptomyces galilaeus | | 分子名称: | AclR protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Beinker, P, Lohkamp, B, Schneider, G. | | 登録日 | 2006-03-21 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of SnoaL2 and AclR: two putative hydroxylases in the biosynthesis of aromatic polyketide antibiotics
J.Mol.Biol., 359, 2006
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2GEX
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7PHF
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PGA
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PHD
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein, GLYCEROL, S-ADENOSYLMETHIONINE, ... | | 著者 | Grocholski, T, Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PHE
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PGJ
 | | Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-decarboxylate TamK and 10-hydroxylase RdmB, together with a single point mutation F297G | | 分子名称: | Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein,Aclacinomycin 10-hydroxylase RdmB, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-7-methoxy-2,4,5-tris(oxidanyl)-6,11-bis(oxidanylidene)-3,4-dihydro-1H-tetracene-1-carboxylate | | 著者 | Dinis, P, MetsaKetela, M. | | 登録日 | 2021-08-14 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
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7PG7
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7QZJ
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4BJ8
 | | Zebavidin | | 分子名称: | BIOTIN, GLYCEROL, ZEBAVIDIN | | 著者 | Airenne, T.T, Parthiban, M, Niederhauser, B, Zmurko, J, Kulomaa, M.S, Hytonen, V.P, Johnson, M.S. | | 登録日 | 2013-04-17 | | 公開日 | 2013-11-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Zebavidin
Plos One, 8, 2013
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