7PHD

Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-decarboxylase TamK

Summary for 7PHD

Entry DOI	10.2210/pdb7phd/pdb
Related	1TW2
Descriptor	Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein, SULFATE ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	carminomycin-4-o-methyltransferase variant; chimeragenesis; tsukubarubicin 10-decarboxylase; biosynthetic protein, biosynthetic protein
Biological source	Streptomyces peucetius More
Total number of polymer chains	2
Total formula weight	82885.77
Authors	Grocholski, T.,Dinis, P.,MetsaKetela, M. (deposition date: 2021-08-17, release date: 2022-09-07, Last modification date: 2024-02-07)
Primary citation	Dinis, P.,Tirkkonen, H.,Wandi, B.N.,Siitonen, V.,Niemi, J.,Grocholski, T.,Metsa-Ketela, M. Evolution-inspired engineering of anthracycline methyltransferases. Pnas Nexus, 2:pgad009-pgad009, 2023 Cited by PubMed: 36874276 DOI: 10.1093/pnasnexus/pgad009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation