4APO
| AIP TPR domain in complex with human Tomm20 peptide | 分子名称: | AH RECEPTOR-INTERACTING PROTEIN, DODECAETHYLENE GLYCOL, MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG, ... | 著者 | Morgan, R.M.L, Roe, S.M, Pearl, L.H, Prodromou, C. | 登録日 | 2012-04-04 | 公開日 | 2013-01-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition. Plos One, 7, 2012
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4AIF
| AIP TPR domain in complex with human Hsp90 peptide | 分子名称: | AH RECEPTOR-INTERACTING PROTEIN, HEAT SHOCK PROTEIN HSP 90-ALPHA, SULFATE ION | 著者 | Morgan, R.M.L, Roe, S.M, Pearl, L.H, Prodromou, C. | 登録日 | 2012-02-09 | 公開日 | 2013-01-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | 主引用文献 | Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition. Plos One, 7, 2012
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8C4A
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7OJS
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7OJR
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7OLH
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7OML
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7OPP
| Crystal structure of the Rab27a fusion with Slp2a-RBDa1 effector for SF4 pocket drug targeting | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Synaptotagmin-like protein 2,Ras-related protein Rab-27A | 著者 | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | 登録日 | 2021-06-01 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13, 2022
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7OPQ
| Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CA1 in C188 | 分子名称: | 1-[(2~{S})-2-(4-methoxyphenyl)pyrrolidin-1-yl]propan-1-one, GLYCEROL, MAGNESIUM ION, ... | 著者 | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | 登録日 | 2021-06-01 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13, 2022
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7OPR
| Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CB1 in C123 | 分子名称: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | 登録日 | 2021-06-01 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13, 2022
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7TSR
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7TSU
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7TSS
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7TSV
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7WYP
| Structure of the SARS-COV-2 main protease with EN102 inhibitor | 分子名称: | 3C-like proteinase, N-(1,3-benzothiazol-2-ylmethyl)-N-cyclopropyl-prop-2-enamide | 著者 | Qin, B, Hou, P, Gao, X, Cui, S. | 登録日 | 2022-02-16 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease. Acta Pharm Sin B, 12, 2022
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7WYL
| Structure of the EV71 3Cpro with 337 inhibitor | 分子名称: | 3C protein, N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide | 著者 | Qin, B, Hou, P, Gao, X, Cui, S. | 登録日 | 2022-02-16 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease. Acta Pharm Sin B, 12, 2022
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7WYO
| Structure of the EV71 3Cpro with 338 inhibitor | 分子名称: | 3C protein, N-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylmethyl)prop-2-enamide | 著者 | Qin, B, Hou, P, Gao, X, Cui, S. | 登録日 | 2022-02-16 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.402 Å) | 主引用文献 | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease. Acta Pharm Sin B, 12, 2022
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7WYM
| Structure of the SARS-COV-2 main protease with 337 inhibitor | 分子名称: | 3C-like proteinase nsp5, N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide | 著者 | Qin, B, Hou, P, Gao, X, Cui, S. | 登録日 | 2022-02-16 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease. Acta Pharm Sin B, 12, 2022
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6I3Y
| Crystal structure of the human mitochondrial PRELID1K58V-TRIAP1 complex with PS | 分子名称: | DODECYL-BETA-D-MALTOSIDE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, PRELI domain-containing protein 1, ... | 著者 | Miliara, X, Berry, J.-L, Morgan, R.M.L, Matthews, S.J. | 登録日 | 2018-11-08 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun, 10, 2019
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6I4Y
| X-ray structure of the human mitochondrial PRELID3b-TRIAP1 complex | 分子名称: | Maltose transport system, substrate-binding protein,TP53-regulated inhibitor of apoptosis 1, PRELI domain containing protein 3B, ... | 著者 | Miliara, X, Berry, J.-L, Morgan, R.M.L, Matthews, S.J. | 登録日 | 2018-11-12 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun, 10, 2019
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6I3V
| x-ray structure of the human mitochondrial PRELID1 in complex with TRIAP1 | 分子名称: | CHLORIDE ION, MYRISTIC ACID, PRELI domain-containing protein 1, ... | 著者 | Berry, J.L, Miliara, X, Morgan, R.M.L, Matthews, S.J. | 登録日 | 2018-11-07 | 公開日 | 2019-03-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun, 10, 2019
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8A6O
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8A6P
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8A6R
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8A6G
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