7OPR
Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CB1 in C123
Summary for 7OPR
Entry DOI | 10.2210/pdb7opr/pdb |
Descriptor | Synaptotagmin-like protein 2,Ras-related protein Rab-27A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | gtpase, exosome, acrylamide, cysteine-reactive, exocytosis |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 54224.87 |
Authors | Jamshidiha, M.,Tersa, M.,Lanyon-Hogg, T.,Perez-Dorado, I.,Sutherell, C.L.,De Vita, E.,Morgan, R.M.L.,Tate, E.W.,Cota, E. (deposition date: 2021-06-01, release date: 2022-04-06, Last modification date: 2024-01-31) |
Primary citation | Jamshidiha, M.,Lanyon-Hogg, T.,Sutherell, C.L.,Craven, G.B.,Tersa, M.,De Vita, E.,Brustur, D.,Perez-Dorado, I.,Hassan, S.,Petracca, R.,Morgan, R.M.,Sanz-Hernandez, M.,Norman, J.C.,Armstrong, A.,Mann, D.J.,Cota, E.,Tate, E.W. Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13:150-155, 2022 Cited by PubMed: 35308027DOI: 10.1039/d1md00225b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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