3L4Y
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![BU of 3l4y by Molmil](/molmil-images/mine/3l4y) | Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8II | 分子名称: | (1S,2R,3S,4R)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2009-12-21 | 公開日 | 2010-02-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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3L4X
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![BU of 3l4x by Molmil](/molmil-images/mine/3l4x) | Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8 | 分子名称: | (1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2009-12-21 | 公開日 | 2010-02-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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3L4T
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![BU of 3l4t by Molmil](/molmil-images/mine/3l4t) | Crystal complex of N-terminal Human Maltase-Glucoamylase with BJ2661 | 分子名称: | (1R,2S)-1-[(1S)-1,2-dihydroxyethyl]-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-2-hydroxypropyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltase-glucoamylase, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2009-12-21 | 公開日 | 2010-02-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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5VIO
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![BU of 5vio by Molmil](/molmil-images/mine/5vio) | Crystal structure of ASK1 kinase domain with a potent inhibitor (analog 13) | 分子名称: | 4-methoxy-N~1~-methyl-N~3~-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzene-1,3-dicarboxamide, Mitogen-activated protein kinase kinase kinase 5 | 著者 | Jasti, J, Chang, J, Kurumbail, R. | 登録日 | 2017-04-17 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors. Eur J Med Chem, 145, 2017
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5VIL
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![BU of 5vil by Molmil](/molmil-images/mine/5vil) | Crystal structure of ASK1 kinase domain with a potent inhibitor (analog 6) | 分子名称: | 2-methoxy-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase kinase kinase 5 | 著者 | Jasti, J, Chang, J, Kurumbail, R. | 登録日 | 2017-04-17 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors. Eur J Med Chem, 145, 2017
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3LPP
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![BU of 3lpp by Molmil](/molmil-images/mine/3lpp) | Crystal complex of N-terminal sucrase-isomaltase with kotalanol | 分子名称: | (1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2010-02-05 | 公開日 | 2010-03-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J.Biol.Chem., 285, 2010
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3LPO
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![BU of 3lpo by Molmil](/molmil-images/mine/3lpo) | Crystal structure of the N-terminal domain of sucrase-isomaltase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sucrase-isomaltase, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2010-02-05 | 公開日 | 2010-03-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J.Biol.Chem., 285, 2010
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3JXB
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![BU of 3jxb by Molmil](/molmil-images/mine/3jxb) | |
3JXC
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![BU of 3jxc by Molmil](/molmil-images/mine/3jxc) | |
3JXD
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![BU of 3jxd by Molmil](/molmil-images/mine/3jxd) | |
3L4V
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![BU of 3l4v by Molmil](/molmil-images/mine/3l4v) | Crystal complex of N-terminal Human Maltase-Glucoamylase with kotalanol | 分子名称: | (1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sim, L, Rose, D.R. | 登録日 | 2009-12-21 | 公開日 | 2010-02-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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6MNY
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![BU of 6mny by Molmil](/molmil-images/mine/6mny) | |
4KS3
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![BU of 4ks3 by Molmil](/molmil-images/mine/4ks3) | Influenza Neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(3-hydroxypropyl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | 分子名称: | (3S,4R,5R)-4-(acetylamino)-3-[4-(3-hydroxypropyl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | 著者 | Kerry, P.S, Russell, R.J.M. | 登録日 | 2013-05-17 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
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4KS2
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![BU of 4ks2 by Molmil](/molmil-images/mine/4ks2) | Influenza Neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-carbamimidamido-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | 分子名称: | (3S,4R,5R)-4-(acetylamino)-3-carbamimidamido-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | 著者 | Kerry, P.S, Russell, R.J.M. | 登録日 | 2013-05-17 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
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4KS4
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![BU of 4ks4 by Molmil](/molmil-images/mine/4ks4) | Influenza Neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-{4-[(1R)-1-hydroxypropyl]-1H-1,2,3-triazol-1-yl}-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | 分子名称: | (3S,4R,5R)-4-(acetylamino)-3-{4-[(1R)-1-hydroxypropyl]-1H-1,2,3-triazol-1-yl}-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | 著者 | Kerry, P.S, Russell, R.J.M. | 登録日 | 2013-05-17 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
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4KS5
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![BU of 4ks5 by Molmil](/molmil-images/mine/4ks5) | Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | 分子名称: | (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | 著者 | Kerry, P.S, Russell, R.J.M. | 登録日 | 2013-05-17 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | 主引用文献 | Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
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4KS1
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![BU of 4ks1 by Molmil](/molmil-images/mine/4ks1) | Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-amino-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | 分子名称: | (3S,4R,5R)-4-(acetylamino)-3-amino-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Kerry, P.S, Russell, R.J.M. | 登録日 | 2013-05-17 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
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2NYA
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![BU of 2nya by Molmil](/molmil-images/mine/2nya) | Crystal structure of the periplasmic nitrate reductase (NAP) from Escherichia coli | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, MOLYBDENUM(VI) ION, ... | 著者 | Jepson, B.J.N, Richardson, D.J, Hemmings, A.M. | 登録日 | 2006-11-20 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Spectropotentiometric and structural analysis of the periplasmic nitrate reductase from Escherichia coli J.Biol.Chem., 282, 2007
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7BY6
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![BU of 7by6 by Molmil](/molmil-images/mine/7by6) | Plasmodium vivax cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD1389 | 分子名称: | (3S,4R,8R,9R,10S)-N-(4-cyclopropyloxyphenyl)-10-(methoxymethyl)-3,4-bis(oxidanyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain, ... | 著者 | Malhotra, N, Manmohan, S, Harlos, K, Melillo, B, Schreiber, S.L, Manickam, Y, Sharma, S. | 登録日 | 2020-04-21 | 公開日 | 2020-11-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | 主引用文献 | Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines. Nat Commun, 12, 2021
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6ICE
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![BU of 6ice by Molmil](/molmil-images/mine/6ice) | Crystal structure of Hamster MIF | 分子名称: | Macrophage migration inhibitory factor | 著者 | Sundaram, R, Vasudevan, D. | 登録日 | 2018-09-05 | 公開日 | 2019-09-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer. Sci Rep, 9, 2019
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6XCR
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![BU of 6xcr by Molmil](/molmil-images/mine/6xcr) | NMR structure of Ost4 in DPC micelles | 分子名称: | Oligosaccharyltransferase | 著者 | Chaudhary, B.P. | 登録日 | 2020-06-09 | 公開日 | 2021-02-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR and MD simulations reveal the impact of the V23D mutation on the function of yeast oligosaccharyltransferase subunit Ost4. Glycobiology, 31, 2021
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6XCU
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![BU of 6xcu by Molmil](/molmil-images/mine/6xcu) | |