4OPE
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![BU of 4ope by Molmil](/molmil-images/mine/4ope) | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS7 | 分子名称: | NITRATE ION, NRPS/PKS | 著者 | Osipiuk, J, Mack, J, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4OPF
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![BU of 4opf by Molmil](/molmil-images/mine/4opf) | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS8 | 分子名称: | NRPS/PKS | 著者 | Osipiuk, J, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4OQJ
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![BU of 4oqj by Molmil](/molmil-images/mine/4oqj) | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmQ KS1 | 分子名称: | GLYCEROL, PHOSPHATE ION, PKS, ... | 著者 | Nocek, B, Mack, J, Endras, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-09 | 公開日 | 2014-03-19 | 最終更新日 | 2016-11-02 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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7BZ7
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![BU of 7bz7 by Molmil](/molmil-images/mine/7bz7) | Template lasso peptide C24 mutant F15Y | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7CRN
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![BU of 7crn by Molmil](/molmil-images/mine/7crn) | |
6ZRE
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![BU of 6zre by Molmil](/molmil-images/mine/6zre) | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | 分子名称: | Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ... | 著者 | Ntsogo Enguene, Y.V, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I. | 登録日 | 2020-07-13 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa. To Be Published
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8H6Q
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![BU of 8h6q by Molmil](/molmil-images/mine/8h6q) | Class I sesquiterpene synthase BCBOT2 (apo) | 分子名称: | Presilphiperfolan-8-beta-ol synthase | 著者 | Lou, T.T, Ma, M. | 登録日 | 2022-10-18 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
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8H6U
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![BU of 8h6u by Molmil](/molmil-images/mine/8h6u) | Class I sesquiterpene synthase BCBOT2 (complex) | 分子名称: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE 2-, ... | 著者 | Lou, T.T, Ma, M. | 登録日 | 2022-10-18 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
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8H4P
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![BU of 8h4p by Molmil](/molmil-images/mine/8h4p) | class I sesquiterpene synthase | 分子名称: | Longiborneol synthase CLM1, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ... | 著者 | Li, A.N, Lou, T.T, Ma, M. | 登録日 | 2022-10-11 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
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8H72
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![BU of 8h72 by Molmil](/molmil-images/mine/8h72) | Class I sesquiterpene synthase DbPROS (complex) | 分子名称: | Delta(6)-protoilludene synthase K435DRAFT_659367, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium | 著者 | Lou, T.T, Ma, M. | 登録日 | 2022-10-18 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
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7BZ9
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![BU of 7bz9 by Molmil](/molmil-images/mine/7bz9) | Template lasso peptide C24 mutant I4A | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7BZA
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![BU of 7bza by Molmil](/molmil-images/mine/7bza) | Template lasso peptide C24 | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7BZ8
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![BU of 7bz8 by Molmil](/molmil-images/mine/7bz8) | Template lasso peptide C24 mutant V3A | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-04-27 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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7DXO
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7E4M
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![BU of 7e4m by Molmil](/molmil-images/mine/7e4m) | |
7E4O
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![BU of 7e4o by Molmil](/molmil-images/mine/7e4o) | |
7E4N
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![BU of 7e4n by Molmil](/molmil-images/mine/7e4n) | Crystal structure of Sat1646 | 分子名称: | MAGNESIUM ION, Sat1646 | 著者 | Yu, J.H, Xing, B.Y, Ma, M. | 登録日 | 2021-02-14 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis Commun Chem, 4, 2021
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7JTS
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![BU of 7jts by Molmil](/molmil-images/mine/7jts) | Stalk of radial spoke 1 attached with doublet microtubule from Chlamydomonas reinhardtii | 分子名称: | Calmodulin, Dynein 8 kDa light chain, flagellar outer arm, ... | 著者 | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | 登録日 | 2020-08-18 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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3IFU
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![BU of 3ifu by Molmil](/molmil-images/mine/3ifu) | The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Leader Protease Nsp1 | 分子名称: | Non-structural protein, ZINC ION | 著者 | Sun, Y, Xue, F, Guo, Y, Ma, M, Lou, Z, Rao, Z. | 登録日 | 2009-07-26 | 公開日 | 2009-10-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Crystal structure of porcine reproductive and respiratory syndrome virus leader protease Nsp1alpha J.Virol., 83, 2009
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7XP7
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![BU of 7xp7 by Molmil](/molmil-images/mine/7xp7) | Crystal Structure of the Flavoprotein ColB1 Catalyzing Assembly Line-Tethered Cysteine Dehydrogenation | 分子名称: | Cyclohexanecarboxyl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Ma, X.Y, Tang, Z.J, Liu, W, Ma, M. | 登録日 | 2022-05-03 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-Based Mechanistic Insights into ColB1, a Flavoprotein Functioning in-trans in the 2,2'-Bipyridine Assembly Line for Cysteine Dehydrogenation. Acs Chem.Biol., 18, 2023
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4HX6
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![BU of 4hx6 by Molmil](/molmil-images/mine/4hx6) | Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 | 分子名称: | ACETATE ION, Oxidoreductase, SULFATE ION | 著者 | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-09 | 公開日 | 2012-11-28 | 最終更新日 | 2016-12-07 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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4HVM
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![BU of 4hvm by Molmil](/molmil-images/mine/4hvm) | Crystal structure of tallysomycin biosynthesis protein TlmII | 分子名称: | SULFATE ION, TlmII | 著者 | Chang, C, Bigelow, L, Bearden, J, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-06 | 公開日 | 2012-11-21 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Crystal structure of tallysomycin biosynthesis protein TlmII To be Published
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4I4K
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![BU of 4i4k by Molmil](/molmil-images/mine/4i4k) | Streptomyces globisporus C-1027 9-membered enediyne conserved protein SgcE6 | 分子名称: | CITRIC ACID, GLYCEROL, PENTAETHYLENE GLYCOL, ... | 著者 | Kim, Y, Bigelow, L, Clancy, S, Babnigg, J, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-27 | 公開日 | 2012-12-12 | 最終更新日 | 2016-12-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027. J Antibiot (Tokyo), 69, 2016
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4IAG
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![BU of 4iag by Molmil](/molmil-images/mine/4iag) | Crystal structure of ZbmA, the zorbamycin binding protein from Streptomyces flavoviridis | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Zbm binding protein | 著者 | Cuff, M.E, Bigelow, L, Bruno, C.J.P, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-12-06 | 公開日 | 2013-02-20 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry, 54, 2015
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4I19
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![BU of 4i19 by Molmil](/molmil-images/mine/4i19) | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. | 分子名称: | ACETATE ION, Epoxide hydrolase, FORMIC ACID | 著者 | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-20 | 公開日 | 2012-12-05 | 最終更新日 | 2013-01-30 | 実験手法 | X-RAY DIFFRACTION (2.148 Å) | 主引用文献 | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. To be Published
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