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4PD5
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BU of 4pd5 by Molmil
Crystal structure of vcCNT-7C8C bound to gemcitabine
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, GEMCITABINE, NupC family protein, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-17
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PDA
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BU of 4pda by Molmil
Structure of vcCNT-7C8C bound to cytidine
分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-17
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.608 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PD6
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BU of 4pd6 by Molmil
Crystal structure of vcCNT-7C8C bound to uridine
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, SODIUM ION, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-17
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PD8
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BU of 4pd8 by Molmil
Structure of vcCNT-7C8C bound to pyrrolo-cytidine
分子名称: 6-methyl-3-(beta-D-ribofuranosyl)-3,7-dihydro-2H-pyrrolo[2,3-d]pyrimidin-2-one, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-17
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PB2
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BU of 4pb2 by Molmil
Structure of vcCNT-7C8C bound to 5-fluorouridine
分子名称: 5-FLUOROURIDINE, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-11
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PD7
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BU of 4pd7 by Molmil
Structure of vcCNT bound to zebularine
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, SODIUM ION, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-17
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.909 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PB1
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BU of 4pb1 by Molmil
Structure of vcCNT-7C8C bound to ribavirin
分子名称: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-11
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
4PD9
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BU of 4pd9 by Molmil
Structure of vcCNT-7C8C bound to adenosine
分子名称: ADENOSINE, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ...
著者Johnson, Z.L, Lee, S.-Y.
登録日2014-04-17
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.096 Å)
主引用文献Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Elife, 3, 2014
5T77
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BU of 5t77 by Molmil
Crystal structure of the MOP flippase MurJ
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, ...
著者Kuk, A.C.Y, Lee, S.-Y.
登録日2016-09-02
公開日2016-12-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the MOP flippase MurJ in an inward-facing conformation.
Nat. Struct. Mol. Biol., 24, 2017
8ET7
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BU of 8et7 by Molmil
Cryo-EM structure of the organic cation transporter 1 in complex with diphenhydramine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET8
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BU of 8et8 by Molmil
Cryo-EM structure of the organic cation transporter 1 in complex with verapamil
分子名称: (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET9
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BU of 8et9 by Molmil
Cryo-EM structure of the organic cation transporter 2 in complex with 1-methyl-4-phenylpyridinium
分子名称: 1-methyl-4-phenylpyridin-1-ium, OCT2
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET6
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BU of 8et6 by Molmil
Cryo-EM structure of the organic cation transporter 1 in the apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8FCB
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BU of 8fcb by Molmil
Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK1016790A
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, ...
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
8TZK
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BU of 8tzk by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, shortened
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Hao, A, Lee, S.-Y.
登録日2023-08-27
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZJ
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BU of 8tzj by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Hao, A, Lee, S.-Y.
登録日2023-08-27
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZL
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BU of 8tzl by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, full-length
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Hao, A, Lee, S.-Y.
登録日2023-08-27
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZ4
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BU of 8tz4 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZ2
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BU of 8tz2 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZD
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BU of 8tzd by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZ1
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BU of 8tz1 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
分子名称: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZ7
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BU of 8tz7 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZ5
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BU of 8tz5 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZ6
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BU of 8tz6 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
8TZA
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BU of 8tza by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
分子名称: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024

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件を2024-10-30に公開中

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