2EDC
 
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2EDA
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7JKM
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1LKK
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1LKL
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2KLJ
 | | Solution Structure of gammaD-Crystallin with RDC and SAXS | | 分子名称: | Gamma-crystallin D | | 著者 | Wang, J, Zuo, X, Yu, P, Byeon, I, Jung, J, Gronenborn, A.M, Wang, Y. | | 登録日 | 2009-07-06 | | 公開日 | 2009-10-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | | 主引用文献 | Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
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1B6G
 | | HALOALKANE DEHALOGENASE AT PH 5.0 CONTAINING CHLORIDE | | 分子名称: | CHLORIDE ION, GLYCEROL, HALOALKANE DEHALOGENASE, ... | | 著者 | Ridder, I.S, Rozeboom, H.J, Dijkstra, B.W. | | 登録日 | 1999-01-14 | | 公開日 | 1999-07-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 refined at 1.15 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
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1AQ6
 | | STRUCTURE OF L-2-HALOACID DEHALOGENASE FROM XANTHOBACTER AUTOTROPHICUS | | 分子名称: | FORMIC ACID, L-2-HALOACID DEHALOGENASE | | 著者 | Ridder, I.S, Rozeboom, H.J, Kalk, K.H, Dijkstra, B.W. | | 登録日 | 1997-08-07 | | 公開日 | 1998-01-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Three-dimensional structure of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 complexed with the substrate-analogue formate.
J.Biol.Chem., 272, 1997
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8UWC
 | | Site-one protease without SPRING | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane-bound transcription factor site-1 protease | | 著者 | Kober, D.L. | | 登録日 | 2023-11-06 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain.
Nat Commun, 15, 2024
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7O7K
 | | Crystal structure of the human DYRK1A kinase domain bound to abemaciclib | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kaltheuner, I.H, Anand, K, Geyer, M. | | 登録日 | 2021-04-13 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.
Nat Commun, 12, 2021
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7O7I
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7O7J
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7AC0
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8UW8
 | | Site-one protease and SPRING | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Membrane-bound transcription factor site-1 protease, ... | | 著者 | Kober, D.L. | | 登録日 | 2023-11-06 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain.
Nat Commun, 15, 2024
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1EDD
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1EDB
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3K2M
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7PZC
 | | Cryo-EM structure of the NLRP3 decamer bound to the inhibitor CRID3 | | 分子名称: | 1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... | | 著者 | Hochheiser, I.V, Pilsl, M, Hagelueken, G, Engel, C, Geyer, M. | | 登録日 | 2021-10-12 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.
Nature, 604, 2022
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7QE5
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7QDA
 | | Crystal structure of CalpL | | 分子名称: | CalpL, SULFATE ION, TETRAETHYLENE GLYCOL, ... | | 著者 | Schneberger, N, Hagelueken, G. | | 登録日 | 2021-11-26 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-02-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
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8P81
 | | Crystal structure of human Cdk12/Cyclin K in complex with inhibitor SR-4835 | | 分子名称: | Cyclin-K, Cyclin-dependent kinase 12, ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | | 著者 | Anand, K, Schmitz, M, Geyer, M. | | 登録日 | 2023-05-31 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation.
J.Biol.Chem., 300, 2023
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2HAD
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7Z1X
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8B0R
 | | Structure of the CalpL/cA4 complex | | 分子名称: | Cyclic tetraadenosine monophosphate (cA4), SMODS-associated and fused to various effectors domain-containing protein, SULFATE ION, ... | | 著者 | Schneberger, N, Hagelueken, G. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
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8B0U
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