5IIE
 
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5IBT
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5IBL
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5EWI
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5F6H
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5F6J
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5F6I
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5F96
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5F9O
 | | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.09 in complex with HIV-1 clade A/E 93TH057 gp120 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CH235.09 Light chain, ... | | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | | 登録日 | 2015-12-10 | | 公開日 | 2016-03-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
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5F9W
 | | Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ... | | 著者 | Chen, L, Zhou, T, Kwong, P.D. | | 登録日 | 2015-12-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8911 Å) | | 主引用文献 | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
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4QHK
 | | UCA (unbound) from CH103 Lineage | | 分子名称: | UCA heavy chain, UCA light chain | | 著者 | Fera, D, Harrison, S.C. | | 登録日 | 2014-05-28 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.487 Å) | | 主引用文献 | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHL
 | | I3.2 (unbound) from CH103 Lineage | | 分子名称: | I3 heavy chain, UCA light chain | | 著者 | Fera, D, Harrison, S.C. | | 登録日 | 2014-05-28 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.153 Å) | | 主引用文献 | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHN
 | | I2 (unbound) from CH103 Lineage | | 分子名称: | I2 heavy chain, I2 light chain | | 著者 | Fera, D, Harrison, S.C. | | 登録日 | 2014-05-28 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHM
 | | I3.1 (unbound) from CH103 Lineage | | 分子名称: | I2 light chain, I3 heavy chain | | 著者 | Fera, D, Harrison, S.C. | | 登録日 | 2014-05-28 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4HKB
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4HQQ
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4HK3
 | | I2 Fab (unbound) from CH65-CH67 Lineage | | 分子名称: | I2 heavy chain, I2 light chain | | 著者 | Schmidt, A.G, Harrison, S.C. | | 登録日 | 2012-10-14 | | 公開日 | 2012-11-21 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4HKX
 | | Influenza hemagglutinin in complex with CH67 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ... | | 著者 | Schmidt, A.G, Harrison, S.C. | | 登録日 | 2012-10-15 | | 公開日 | 2012-11-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4HK0
 | | UCA Fab (unbound) from CH65-CH67 Lineage | | 分子名称: | UCA heavy chain, UCA light chain | | 著者 | Schmidt, A.G, Harrison, S.C. | | 登録日 | 2012-10-14 | | 公開日 | 2012-11-21 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | | 主引用文献 | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4HPY
 | | Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide | | 分子名称: | CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ... | | 著者 | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | | 登録日 | 2012-10-24 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
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4HPO
 | | Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide | | 分子名称: | CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ... | | 著者 | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | | 登録日 | 2012-10-24 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.694 Å) | | 主引用文献 | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
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4JAN
 | | crystal structure of broadly neutralizing antibody CH103 in complex with HIV-1 gp120 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ... | | 著者 | Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D. | | 登録日 | 2013-02-18 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
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4JAM
 | | Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103 | | 分子名称: | 1,2-ETHANEDIOL, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ... | | 著者 | Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D. | | 登録日 | 2013-02-18 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
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5U3L
 | | Crystal Structure of DH511.2 Fab in Complex with HIV-1 gp41 MPER 670-683 Peptide | | 分子名称: | DH511.2 Fab Heavy Chain, DH511.2 Fab Light Chain, gp41 MPER peptide | | 著者 | Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F. | | 登録日 | 2016-12-02 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | | 主引用文献 | Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
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5TPP
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