4HK0

UCA Fab (unbound) from CH65-CH67 Lineage

Summary for 4HK0

• Entry DOI: 10.2210/pdb4hk0/pdb
• Related: 4HK3 4HKB 4HKX
• Descriptor: UCA heavy chain, UCA light chain (3 entities in total)
• Functional Keywords: fab fragment, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 96807.45

Authors

Schmidt, A.G.,Harrison, S.C. (deposition date: 2012-10-14, release date: 2012-11-21, Last modification date: 2017-11-15)

• Primary citation: Schmidt, A.G.,Xu, H.,Khan, A.R.,O'Donnell, T.,Khurana, S.,King, L.R.,Manischewitz, J.,Golding, H.,Suphaphiphat, P.,Carfi, A.,Settembre, E.C.,Dormitzer, P.R.,Kepler, T.B.,Zhang, R.,Moody, M.A.,Haynes, B.F.,Liao, H.X.,Shaw, D.E.,Harrison, S.C.; Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.; Proc.Natl.Acad.Sci.USA, 110:264-269, 2013; PubMed: 23175789; DOI: 10.1073/pnas.1218256109

Experimental method

X-RAY DIFFRACTION (2.497 Å)