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1R9W
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BU of 1r9w by Molmil
Crystal Structure of the DNA-binding domain of the human papillomavirus type 18 (HPV-18) replication initiation protein E1
分子名称: Replication protein E1
著者Auster, A.S, Joshua-Tor, L.
登録日2003-10-31
公開日2003-11-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding.
J.Biol.Chem., 279, 2004
1R6Z
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BU of 1r6z by Molmil
The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
分子名称: Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L.
登録日2003-10-17
公開日2004-01-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003
6OU9
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Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric unit in T=3 symmetry
分子名称: Major capsid protein
著者Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
登録日2019-05-04
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUT
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BU of 6out by Molmil
Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry
分子名称: Capsid protein VP1
著者Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
登録日2019-05-05
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUC
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BU of 6ouc by Molmil
Asymmetric focsued reconstruction of human norovirus GII.2 Snow Mountain Virus strain VLP asymmetric unit in T=1 symmetry
分子名称: Viral protein 1, ZINC ION
著者Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
登録日2019-05-04
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUU
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BU of 6ouu by Molmil
Symmetric reconstruction of human norovirus GII.4 Minerva strain VLP in T=4 symmetry
分子名称: Major capsid protein
著者Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
登録日2019-05-05
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
1U04
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BU of 1u04 by Molmil
Crystal structure of full length Argonaute from Pyrococcus furiosus
分子名称: hypothetical protein PF0537
著者Song, J.J, Smith, S.K, Hannon, G.J, Joshua-Tor, L.
登録日2004-07-12
公開日2004-08-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
Science, 305, 2004
4F3T
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BU of 4f3t by Molmil
Human Argonaute-2 - miR-20a complex
分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3')
著者Elkayam, E, Kuhn, C.-D, Tocilj, A, Joshua-Tor, L.
登録日2012-05-09
公開日2012-05-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Structure of Human Argonaute-2 in Complex with miR-20a.
Cell(Cambridge,Mass.), 150, 2012
4GGK
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BU of 4ggk by Molmil
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate
分子名称: Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION
著者Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L.
登録日2012-08-06
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
9ASP
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Human Drosha and DGCR8 in complex with Pri-let-7a1
分子名称: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
著者Garg, A, Joshua-Tor, L.
登録日2024-02-26
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献RNAi_protein_a1
To Be Published
9ASO
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BU of 9aso by Molmil
Human Drosha and DGCR8 in complex with Pri-let-7a2
分子名称: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
著者Garg, A, Joshua-Tor, L.
登録日2024-02-26
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献RNAi_protein_a2
To Be Published
9ASN
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BU of 9asn by Molmil
Human Drosha and DGCR8 in complex with Pri-miR-98
分子名称: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
著者Garg, A, Joshua-Tor, L.
登録日2024-02-26
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献RNAi_protein_98
To Be Published
9ASQ
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BU of 9asq by Molmil
Human Drosha, DGCR8 and SRSF3 in complex with Pri-let-7f1
分子名称: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
著者Garg, A, Joshua-Tor, L.
登録日2024-02-26
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献RNAi_protein_f1_SR
To Be Published
9ASM
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BU of 9asm by Molmil
Human Drosha and DGCR8 in complex with Pri-let-7f1
分子名称: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
著者Garg, A, Joshua-Tor, L.
登録日2024-02-26
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献RNAi_protein_f1
To Be Published
4GGJ
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BU of 4ggj by Molmil
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD)
分子名称: Mitochondrial cardiolipin hydrolase, ZINC ION
著者Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L.
登録日2012-08-06
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
7JPQ
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BU of 7jpq by Molmil
ORC-O2-5: Human Origin Recognition Complex (ORC) with subunits 2,3,4,5
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 2, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPS
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BU of 7jps by Molmil
ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPO
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BU of 7jpo by Molmil
ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPR
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BU of 7jpr by Molmil
ORC-OPEN: Human Origin Recognition Complex (ORC) in an open conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
1Z25
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BU of 1z25 by Molmil
Structure of P.furiosus Argonaute with bound Mn2+
分子名称: Argonaute, MANGANESE (II) ION
著者Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
登録日2005-03-07
公開日2005-04-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1Z26
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BU of 1z26 by Molmil
Structure of Pyrococcus furiosus Argonaute with bound tungstate
分子名称: Argonaute, TUNGSTATE(VI)ION
著者Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
登録日2005-03-07
公開日2005-04-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1ZRO
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BU of 1zro by Molmil
Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose
分子名称: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
著者Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
登録日2005-05-19
公開日2005-08-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
1ZRL
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BU of 1zrl by Molmil
Crystal structure of EBA-175 Region II (RII)
分子名称: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
著者Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
登録日2005-05-19
公開日2005-08-09
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
2CB5
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HUMAN BLEOMYCIN HYDROLASE, C73S/DELE455 MUTANT
分子名称: PROTEIN (BLEOMYCIN HYDROLASE)
著者O'Farrell, P.A, Gonzalez, F, Zheng, W, Johnston, S.A, Joshua-Tor, L.
登録日1999-03-02
公開日2000-03-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease.
Structure Fold.Des., 7, 1999
2E00
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BU of 2e00 by Molmil
Crystal structure of N392L mutant of yeast bleomycin hydrolase
分子名称: Cysteine proteinase 1
著者O'Farrell, P.A, Joshua-Tor, L.
登録日2006-10-01
公開日2007-11-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure
Biochem.J., 401, 2007

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