8HR5
 
 | | Cryo-EM structure of the CnCas12f1-sgRNA-DNA complex | | 分子名称: | DNA (28-MER), DNA (5'-D(*TP*AP*AP*CP*CP*TP*AP*AP*TP*AP*GP*AP*TP*GP*TP*GP*AP*A)-3'), Transposase, ... | | 著者 | Li, F, Ji, Q. | | 登録日 | 2022-12-14 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Structure and engineering of miniature Clostridium novyi CRISPR-Cas12f1 with rare C-rich PAM specificity
To Be Published
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7WJU
 | | Cryo-EM structure of the AsCas12f1-sgRNAv1-dsDNA ternary complex | | 分子名称: | Non-target strand, OrfB_Zn_ribbon domain-containing protein, Target strand, ... | | 著者 | Wu, Z, Liu, D, Shen, H, Ji, Q. | | 登録日 | 2022-01-07 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Structure-directed functional evolution of the miniature CRISPR-AsCas12f1 system
To Be Published
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7EN6
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7EN5
 | | The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate | | 分子名称: | 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Zhang, Y, Chen, W, Ji, Q. | | 登録日 | 2021-04-16 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
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7EN7
 | | The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate | | 分子名称: | (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR | | 著者 | Zhang, Y, Chen, W, Ji, Q. | | 登録日 | 2021-04-16 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
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5C0Z
 | | The structure of oxidized rat cytochrome c at 1.13 angstroms resolution | | 分子名称: | Cytochrome c, somatic, HEME C, ... | | 著者 | Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M. | | 登録日 | 2015-06-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.1236 Å) | | 主引用文献 | Serine-47 phosphorylation of cytochromecin the mammalian brain regulates cytochromecoxidase and caspase-3 activity.
Faseb J., 2019
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6TXZ
 | | FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | | 分子名称: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | | 著者 | Musil, D, Sood, V. | | 登録日 | 2020-01-15 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody.
Oncoimmunology, 9, 2020
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6JV5
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7KN3
 | | Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ... | | 著者 | Liu, H, Zhu, X, Wilson, I.A. | | 登録日 | 2020-11-04 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
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7KN4
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6N1O
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4NPM
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4NPL
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5ZAT
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5ZAS
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5EPO
 | | The three-dimensional structure of Clostridium absonum 7alpha-hydroxysteroid dehydrogenase | | 分子名称: | 7-alpha-hydroxysteroid deydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Lou, D, Wang, B, Wang, F. | | 登録日 | 2015-11-12 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The three-dimensional structure of Clostridium absonum 7 alpha-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition
Sci Rep, 6, 2016
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6JV3
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6IKM
 | | Crystal structure of SpuE-Spermidine in complex with ScFv5 | | 分子名称: | Polyamine transport protein, SPERMIDINE, SULFATE ION, ... | | 著者 | Wu, D, Sun, X. | | 登録日 | 2018-10-16 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.398 Å) | | 主引用文献 | A Potent Anti-SpuE Antibody Allosterically Inhibits Type III Secretion System and Attenuates Virulence of Pseudomonas Aeruginosa.
J.Mol.Biol., 431, 2019
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7WID
 | | Crystal structure of Staphylococcus aureus ClpP in complex with ZG180 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, ... | | 著者 | Wei, B.Y, Gan, J.H, Yang, C.-G. | | 登録日 | 2022-01-03 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nat Commun, 13, 2022
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7WGS
 | | Structure of ClpP from Staphylococcus aureus in complex with (S)-ZG197 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2R)-butan-2-yl]-8-[(1S)-1-naphthalen-1-ylethyl]-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit | | 著者 | Yang, C.-G, Gan, J.H. | | 登録日 | 2021-12-28 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nat Commun, 13, 2022
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7WH5
 | | Crystal structure of human ClpP in complex with ZG180 | | 分子名称: | (6S,9aS)-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... | | 著者 | Wei, B.Y, Gan, J.H, Yang, C.-G. | | 登録日 | 2021-12-29 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nat Commun, 13, 2022
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7XBZ
 | | Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2S)-butan-2-yl]-8-[(1R)-1-naphthalen-1-ylethyl]-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, ... | | 著者 | Wei, B.Y, Gan, J.H, Yang, C.-G. | | 登録日 | 2022-03-22 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nat Commun, 13, 2022
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