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5GHP
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Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-06-20
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.192 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
3L85
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Crystal structure of human NUDT5 complexed with 8-oxo-dGMP
分子名称: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, ADP-sugar pyrophosphatase
著者Arimori, T, Yamagata, Y.
登録日2009-12-29
公開日2011-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
8WWY
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Crystal structure of mouse TIFA/TIFAB heterodimer
分子名称: (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B
著者Nakamura, T.
登録日2023-10-27
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.
Proc.Natl.Acad.Sci.USA, 121, 2024
1QZ1
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Crystal Structure of the Ig 1-2-3 fragment of NCAM
分子名称: Neural cell adhesion molecule 1, 140 kDa isoform
著者Soroka, V, Kolkova, K, Kastrup, J.S, Diederichs, K, Breed, J, Kiselyov, V.V, Poulsen, F.M, Larsen, I.K, Welte, W, Berezin, V, Bock, E, Kasper, C.
登録日2003-09-15
公開日2003-11-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion
Structure, 11, 2003
5MXA
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Structure of unbound Interleukin-23
分子名称: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bloch, Y, Savvides, S.N.
登録日2017-01-22
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
6L9W
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Crystal structure of mouse TIFA (T9E/C36S mutant)
分子名称: TRAF-interacting protein with FHA domain-containing protein A
著者Nakamura, T, Yamagata, Y.
登録日2019-11-11
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Sci Rep, 10, 2020
6L9V
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Crystal structure of mouse TIFA (T9D/C36S mutant)
分子名称: TRAF-interacting protein with FHA domain-containing protein A
著者Nakamura, T, Yamagata, Y.
登録日2019-11-11
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Sci Rep, 10, 2020
6L9U
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Crystal structure of mouse TIFA
分子名称: TRAF-interacting protein with FHA domain-containing protein A
著者Nakamura, T, Yamagata, Y.
登録日2019-11-11
公開日2020-04-01
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Sci Rep, 10, 2020
7EF9
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Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II)
分子名称: Adenine DNA glycosylase, DNA (5'-D(*AP*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), ...
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
7EF8
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Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form I)
分子名称: Adenine DNA glycosylase, DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), ...
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
7EFA
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Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA
分子名称: Adenine DNA glycosylase, Proliferating cell nuclear antigen
著者Nakamura, T, Nakabeppu, Y, Yamagata, Y.
登録日2021-03-21
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
2ZJC
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TNFR1 selectve TNF mutant; R1-6
分子名称: GLYCEROL, Tumor necrosis factor
著者Mukai, Y, Yamagata, Y, Tsutsumi, Y.
登録日2008-03-05
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant
J.Mol.Biol., 385, 2009
3A4D
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Crystal structure of Human Transthyretin (wild-type)
分子名称: GLYCEROL, SULFATE ION, Transthyretin
著者Miyata, M.
登録日2009-07-06
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding
Biochemistry, 2009
1I8L
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HUMAN B7-1/CTLA-4 CO-STIMULATORY COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD80, ...
著者Stamper, C.C, Somers, W.S, Mosyak, L.
登録日2001-03-14
公開日2001-04-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses.
Nature, 410, 2001
8I1C
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Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 9.1
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, GLYCEROL, SODIUM ION
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1A
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Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 8.6
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1I
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Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 7.7
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1D
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Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 7.7
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1E
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Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.0
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I18
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Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 7.7
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I19
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Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 8.0
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1H
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Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 9.7
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, GLYCEROL, SODIUM ION
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1J
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Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 9.7
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I8T
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Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dAMP and Mn2+
分子名称: 2'-DEOXYISOGUANINE-5'-MONOPHOSPHATE, 7,8-dihydro-8-oxoguanine triphosphatase, MANGANESE (II) ION
著者Nakamura, T, Yamagata, Y.
登録日2023-02-05
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
8I1F
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Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.6
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Yamagata, Y.
登録日2023-01-13
公開日2023-03-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023

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