Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4KRZ
DownloadVisualize
BU of 4krz by Molmil
Apo crystal structure of pyruvate kinase (PYK) from Trypanosoma cruzi
分子名称: GLYCEROL, POTASSIUM ION, Pyruvate kinase
著者Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D.
登録日2013-05-17
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of pyruvate kinases display evolutionarily divergent allosteric strategies.
R Soc Open Sci, 1, 2014
1TP7
DownloadVisualize
BU of 1tp7 by Molmil
Crystal Structure of the RNA-dependent RNA Polymerase from Human Rhinovirus 16
分子名称: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, Genome polyprotein, SULFATE ION
著者Appleby, T.C, Luecke, H, Shim, J.H, Wu, J.Z, Cheney, I.W, Zhong, W, Vogeley, L, Hong, Z, Yao, N.
登録日2004-06-15
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
J.Virol., 79, 2005
7F3B
DownloadVisualize
BU of 7f3b by Molmil
cocrystallization of Escherichia coli dihydrofolate reductase (DHFR) and its pyrrolo[3,2-f]quinazoline inhibitor.
分子名称: 7-[(2-fluorophenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, GLYCEROL
著者Wang, H, You, X.F, Yang, X.Y, Li, Y, Hong, W.
登録日2021-06-16
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates.
Eur.J.Med.Chem., 228, 2022
5NF0
DownloadVisualize
BU of 5nf0 by Molmil
Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa
分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, CYD-TRP-TRD-LYS-LYD-LYS-LYD-LYS-TRD-TRP-CYD-GLY, ...
著者Reymond, J.-L, Darbre, T, Stocker, A, Hong, W, van Delden, C, Koehler, T, Luscher, A, Visini, R, Fu, Y, Di Bonaventura, I, He, R.
登録日2017-03-13
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.271 Å)
主引用文献Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.
Chem Sci, 8, 2017
5NES
DownloadVisualize
BU of 5nes by Molmil
Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa
分子名称: 1,3-dimethylbenzene, 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, ...
著者Reymond, J.-L, Darbre, T, Stocker, A, Hong, W, van Delden, C, Koehler, T, Luscher, A, Visini, R, Fu, Y, Di Bonaventura, I, He, R.
登録日2017-03-11
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.606 Å)
主引用文献Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.
Chem Sci, 8, 2017
5NEY
DownloadVisualize
BU of 5ney by Molmil
Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa
分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, CYS-TRD-TRP-LYD-LYS-LYD-LYS-LYD-TRP-TRD-CYS-ALA, ...
著者Reymond, J.-L, Darbre, T, Stocker, A, Hong, W, van Delden, C, Koehler, T, Luscher, A, Visini, R, Fu, Y, Di Bonaventura, I, He, R.
登録日2017-03-13
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.
Chem Sci, 8, 2017
4CXY
DownloadVisualize
BU of 4cxy by Molmil
Crystal structure of human FTO in complex with acylhydrazine inhibitor 21
分子名称: (E)-4-(2-Nicotinoylhydrazinyl)-4-oxobut-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION
著者Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G.
登録日2014-04-09
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Chem Sci, 6, 2015
4CXX
DownloadVisualize
BU of 4cxx by Molmil
Crystal structure of human FTO in complex with acylhydrazine inhibitor 16
分子名称: (2E)-4-{N'-[4-(4-tert-Butyl-benzyl)-pyridine-3-carbonyl]-hydrazino}-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION
著者Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G.
登録日2014-04-09
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Chem Sci, 6, 2015
4CXW
DownloadVisualize
BU of 4cxw by Molmil
Crystal structure of human FTO in complex with subfamily-selective inhibitor 12
分子名称: (2E)-4-[N'-(4-benzyl-pyridine-3-carbonyl)-hydrazino]-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION
著者Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G.
登録日2014-04-09
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Chem Sci, 6, 2015
2V14
DownloadVisualize
BU of 2v14 by Molmil
Kinesin 16B Phox-homology domain (KIF16B)
分子名称: KINESIN-LIKE MOTOR PROTEIN C20ORF23
著者Wilson, M.I, Williams, R.L, Cho, W, Hong, W, Blatner, N.R.
登録日2007-05-21
公開日2007-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structural Basis of Novel Endosome Anchoring Activity of Kif16B Kinesin.
Embo J., 26, 2007
1YHN
DownloadVisualize
BU of 1yhn by Molmil
Structure basis of RILP recruitment by Rab7
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab interacting lysosomal protein, ...
著者Wu, M, Wang, T, Hong, W, Song, H.
登録日2005-01-10
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for recruitment of RILP by small GTPase Rab7.
Embo J., 24, 2005
1T91
DownloadVisualize
BU of 1t91 by Molmil
crystal structure of human small GTPase Rab7(GTP)
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7
著者Song, H, Hong, W, Wu, M, Wang, T.
登録日2004-05-14
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for recruitment of RILP by small GTPase Rab7.
Embo J., 24, 2005
1R4A
DownloadVisualize
BU of 1r4a by Molmil
Crystal Structure of GTP-bound ADP-ribosylation Factor Like Protein 1 (Arl1) and GRIP Domain of Golgin245 COMPLEX
分子名称: ADP-ribosylation factor-like protein 1, Golgi autoantigen, golgin subfamily A member 4, ...
著者Wu, M, Lu, L, Hong, W, Song, H.
登録日2003-10-04
公開日2004-01-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1.
Nat.Struct.Mol.Biol., 11, 2004
2FBM
DownloadVisualize
BU of 2fbm by Molmil
Acetyltransferase domain of CDY1
分子名称: CHLORIDE ION, Y chromosome chromodomain protein 1, telomeric isoform b
著者Min, J.R, Antoshenko, T, Hong, W, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-12-09
公開日2005-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal Structure of Acetyltransferases domain of Human Testis-specific chromodomain protein Y 1
To be Published
5Y15
DownloadVisualize
BU of 5y15 by Molmil
Crystal structure of human DUSP28
分子名称: Dual specificity phosphatase 28, PHOSPHATE ION
著者Ku, B, Hong, W, Kim, S.J, Ryu, S.E.
登録日2017-07-19
公開日2017-11-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
6ABS
DownloadVisualize
BU of 6abs by Molmil
Actin interacting protein 5 (Aip5, mutant)
分子名称: Actin binding protein, PENTAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
著者Sun, J, Ying, X, Toh, J, Hong, W, Miao, Y, Gao, Y.G.
登録日2018-07-23
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization.
Nat Commun, 10, 2019
6ABR
DownloadVisualize
BU of 6abr by Molmil
Actin interacting protein 5 (Aip5, wild type)
分子名称: Actin binding protein
著者Sun, J, Xie, Y, Toh, J.D.W, Hong, W, MIao, Y, Gao, Y.G.
登録日2018-07-23
公開日2019-11-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization.
Nat Commun, 10, 2019
5JIE
DownloadVisualize
BU of 5jie by Molmil
Crystal structure of the Orsay virus delta protein N-terminal fragment (aa 1~66)
分子名称: Protein delta
著者Fan, Y, Guo, Y, Zhong, W, Tao, Y.J.
登録日2016-04-22
公開日2017-02-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1374 Å)
主引用文献Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells.
PLoS Pathog., 13, 2017
1O7T
DownloadVisualize
BU of 1o7t by Molmil
Metal nanoclusters bound to the Ferric Binding Protein from Neisseria gonorrhoeae.
分子名称: HF OXO CLUSTER HF5, HF-OXO-PHOSPHATE CLUSTER PHF, IRON BINDING PROTEIN, ...
著者Alexeev, D, Zu, H, Guo, M, Zhong, W, Hunter, D.J.B, Yang, W, Campopiano, D.J, Sadler, P.J.
登録日2002-11-12
公開日2003-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A novel protein-mineral interface.
Nat. Struct. Biol., 10, 2003
8W9B
DownloadVisualize
BU of 8w9b by Molmil
CryoEM structure of human PI3K-alpha (P85/P110-H1047R) with QR-8557 binding at an allosteric site
分子名称: 1-[(1S)-1-(5-fluoranyl-3-methyl-1-benzofuran-2-yl)-2-methyl-propyl]-3-(1-oxidanylidene-2,3-dihydroisoindol-5-yl)urea, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
著者Huang, X, Ren, X, Zhong, W.
登録日2023-09-05
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures reveal two allosteric inhibition modes of PI3K alpha H1047R involving a re-shaping of the activation loop.
Structure, 2024
8W9A
DownloadVisualize
BU of 8w9a by Molmil
CryoEM structure of human PI3K-alpha (P85/P110-H1047R) with QR-7909 binding at an allosteric site
分子名称: 6-chloranyl-3-[[(1R)-1-[2-(1,3-dihydropyrrolo[3,4-c]pyridin-2-yl)-3,6-dimethyl-4-oxidanylidene-quinazolin-8-yl]ethyl]amino]pyridine-2-carboxylic acid, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
著者Huang, X, Ren, X, Zhong, W.
登録日2023-09-05
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structures reveal two allosteric inhibition modes of PI3K alpha H1047R involving a re-shaping of the activation loop.
Structure, 2024
5WYQ
DownloadVisualize
BU of 5wyq by Molmil
Crystal Structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
分子名称: S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase
著者Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W, McBee, M.E, Maenpuen, S, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M, Chaiyen, P.
登録日2017-01-15
公開日2017-12-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa.
Rna, 2019
1WBY
DownloadVisualize
BU of 1wby by Molmil
CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称: BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ...
著者Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBZ
DownloadVisualize
BU of 1wbz by Molmil
CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称: BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN PRECURSOR, ...
著者Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBX
DownloadVisualize
BU of 1wbx by Molmil
CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称: BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ...
著者Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005

221716

件を2024-06-26に公開中

PDB statisticsPDBj update infoContact PDBjnumon