5NF0

Discovery, crystal structures and atomic force microscopy study of thioether ligated D,L-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa

Summary for 5NF0

Entry DOI	10.2210/pdb5nf0/pdb
Descriptor	Fucose-binding lectin II (PA-IIL), CYD-TRP-TRD-LYS-LYD-LYS-LYD-LYS-TRD-TRP-CYD-GLY, Fragment of ligand, ... (7 entities in total)
Functional Keywords	cyclic peptides, antimicrobials, pseudomonas aeruginosa, antimicrobial protein
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	8
Total formula weight	53539.09
Authors	Reymond, J.-L.,Darbre, T.,Stocker, A.,Hong, W.,van Delden, C.,Koehler, T.,Luscher, A.,Visini, R.,Fu, Y.,Di Bonaventura, I.,He, R. (deposition date: 2017-03-13, release date: 2017-09-13, Last modification date: 2024-01-17)
Primary citation	He, R.,Di Bonaventura, I.,Visini, R.,Gan, B.H.,Fu, Y.,Probst, D.,Luscher, A.,Kohler, T.,van Delden, C.,Stocker, A.,Hong, W.,Darbre, T.,Reymond, J.L. Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chem Sci, 8:7464-7475, 2017 Cited by PubMed: 29163899 DOI: 10.1039/c7sc01599b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.271 Å)

Structure validation