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5TLN
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BU of 5tln by Molmil
BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称: CALCIUM ION, HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE, THERMOLYSIN, ...
著者Matthews, B.W, Holmes, M.A.
登録日1982-02-08
公開日1982-05-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
1KPR
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BU of 1kpr by Molmil
The human non-classical major histocompatibility complex molecule HLA-E
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ...
著者Holmes, M.A, Strong, R.K.
登録日2002-01-02
公開日2003-02-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
1KTL
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BU of 1ktl by Molmil
The human non-classical major histocompatibility complex molecule HLA-E
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ...
著者Holmes, M.A, Strong, R.K.
登録日2002-01-16
公開日2003-02-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
4L8I
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BU of 4l8i by Molmil
Crystal structure of RSV epitope scaffold FFL_005
分子名称: RSV epitope scaffold FFL_005
著者Jardine, J, Correnti, C, Holmes, M.A, Strong, R.K, Schief, W.R.
登録日2013-06-17
公開日2014-02-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
3OMZ
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BU of 3omz by Molmil
Crystal structure of MICA-specific human gamma delta T cell receptor
分子名称: human Vdelta1 gamma delta T cell receptor delta1A/B-3
著者Xu, B, Holmes, M.A, Strong, R.K.
登録日2010-08-27
公開日2011-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystal structure of a {gamma}{delta} T-cell receptor specific for the human MHC class I homolog MICA.
Proc.Natl.Acad.Sci.USA, 108, 2011
4TMN
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BU of 4tmn by Molmil
SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES
分子名称: CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
6TMN
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BU of 6tmn by Molmil
Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond
分子名称: CALCIUM ION, N-[(2R,4S)-4-hydroxy-2-(2-methylpropyl)-4-oxido-7-oxo-9-phenyl-3,8-dioxa-6-aza-4-phosphanonan-1-oyl]-L-leucine, THERMOLYSIN, ...
著者Tronrud, D.E, Holden, H.M, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond.
Science, 235, 1987
3TMN
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THE BINDING OF L-VALYL-L-TRYPTOPHAN TO CRYSTALLINE THERMOLYSIN ILLUSTRATES THE MODE OF INTERACTION OF A PRODUCT OF PEPTIDE HYDROLYSIS
分子名称: CALCIUM ION, THERMOLYSIN, TRYPTOPHAN, ...
著者Holden, H.M, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis.
J.Biol.Chem., 263, 1988
2TMN
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BU of 2tmn by Molmil
CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称: CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ...
著者Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.
Eur.J.Biochem., 157, 1986
1TMN
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BU of 1tmn by Molmil
Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases
分子名称: CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ...
著者Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases
Biochemistry, 23, 1984
1TLP
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BU of 1tlp by Molmil
CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称: CALCIUM ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, THERMOLYSIN, ...
著者Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.
Eur.J.Biochem., 157, 1986
8TLN
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BU of 8tln by Molmil
STRUCTURAL COMPARISON SUGGESTS THAT THERMOLYSIN AND RELATED NEUTRAL PROTEASES UNDERGO HINGE-BENDING MOTION DURING CATALYSIS
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者Tronrud, D, Matthews, B.W.
登録日1993-09-01
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis.
Biochemistry, 31, 1992
1THL
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BU of 1thl by Molmil
Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan
分子名称: CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ...
著者Holland, D.R, Matthews, B.W.
登録日1993-11-17
公開日1994-01-31
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex
Biochemistry, 33, 1994
1TLX
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BU of 1tlx by Molmil
THERMOLYSIN (NATIVE)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-11-02
公開日2000-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
1LNA
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BU of 1lna by Molmil
A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称: CALCIUM ION, COBALT (II) ION, DIMETHYL SULFOXIDE, ...
著者Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNC
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BU of 1lnc by Molmil
A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNE
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BU of 1lne by Molmil
A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称: CADMIUM ION, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNB
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BU of 1lnb by Molmil
A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, FE (III) ION, ...
著者Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
1LNF
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BU of 1lnf by Molmil
A structural analysis of metal substitutions in thermolysin
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者Holland, D.R, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
5TMN
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BU of 5tmn by Molmil
Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
分子名称: CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
1LND
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BU of 1lnd by Molmil
A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日1994-05-13
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of zinc substitutions in the active site of thermolysin.
Protein Sci., 4, 1995
4OB5
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BU of 4ob5 by Molmil
Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10
分子名称: 4E10 antibody germline precursor 7 heavy chain Fv, 4E10 antibody germline precursor 7 light chain Fv, GLYCEROL, ...
著者Jaffe, J.B, Rupert, P.B.
登録日2014-01-06
公開日2014-10-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4ODX
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4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
分子名称: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain
著者Finton, K.A.K.
登録日2014-01-10
公開日2014-10-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4N9G
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BU of 4n9g by Molmil
Crystal Structure of a Computationally Designed RSV-Presenting Epitope Scaffold And Its Elicited Antibody 17HD9
分子名称: Antibody 17HD9, Heavy Chain, Light Chain, ...
著者Carrico, C.T.D, Strong, R.K.
登録日2013-10-21
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
3U9P
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Crystal Structure of Murine Siderocalin in Complex with an Fab Fragment
分子名称: Monoclonal Fab Fragment Heavy Chain, Monoclonal Fab Fragment Light Chain, Neutrophil gelatinase-associated lipocalin
著者Correnti, C, Strong, R.K.
登録日2011-10-19
公開日2013-05-01
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines.
Plos One, 7, 2012

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