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5GUT
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BU of 5gut by Molmil
The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A
分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Chen, S.J, Ye, F.
登録日2016-08-31
公開日2017-09-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.
ACS Chem. Biol., 13, 2018
5GUV
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BU of 5guv by Molmil
The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D
分子名称: DNA (cytosine-5)-methyltransferase 1, ZINC ION
著者Ye, F, Chen, S.J.
登録日2016-08-31
公開日2017-08-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.078 Å)
主引用文献Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.
ACS Chem. Biol., 13, 2018
3K53
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BU of 3k53 by Molmil
Crystal Structure of NFeoB from P. furiosus
分子名称: Ferrous iron transport protein b
著者Eng, E.T, Dong, G, Unger, V.M.
登録日2009-10-06
公開日2010-05-26
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB.
J.Struct.Biol., 170, 2010
4K3J
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BU of 4k3j by Molmil
Crystal structure of Onartuzumab Fab in complex with MET and HGF-beta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hepatocyte growth factor, Hepatocyte growth factor beta chain, ...
著者Ma, X, Starovasnik, M.A.
登録日2013-04-10
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Proc.Natl.Acad.Sci.USA, 110, 2013
3W9S
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BU of 3w9s by Molmil
Crystal Structure Analysis of the N-terminal Receiver domain of Response Regulator PmrA
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OmpR family response regulator in two-component regulatory system with BasS
著者Chen, C, Luo, S.
登録日2013-04-15
公開日2013-07-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella Pneumoniae
J.Biol.Chem., 288, 2013
2CJR
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BU of 2cjr by Molmil
Crystal structure of oligomerization domain of SARS coronavirus nucleocapsid protein.
分子名称: NUCLEOCAPSID PROTEIN
著者Chen, C.-Y, Hsiao, C.-D.
登録日2006-04-06
公開日2007-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Sars Coronavirus Nucleocapsid Protein RNA-Binding Dimerization Domain Suggests a Mechanism for Helical Packaging of Viral RNA.
J.Mol.Biol., 368, 2007
7UIC
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BU of 7uic by Molmil
Mediator-PIC Early (Tail A)
分子名称: Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIL
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BU of 7uil by Molmil
Mediator-PIC Early (Tail A/B Dimer)
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIF
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BU of 7uif by Molmil
Mediator-PIC Early (Core B)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIK
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BU of 7uik by Molmil
Mediator-PIC Early (Tail A + Upstream DNA & Activator)
分子名称: DNA (37-MER), DNA (38-MER), Mediator of RNA polymerase II transcription subunit 14, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-03-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIO
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BU of 7uio by Molmil
Mediator-PIC Early (Composite Model)
分子名称: ALANINE, ASPARTIC ACID, DNA (37-MER), ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-03-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIG
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BU of 7uig by Molmil
Mediator-PIC Early (Mediator A)
分子名称: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UI9
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BU of 7ui9 by Molmil
Core Mediator-PICearly (Copy A)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-28
公開日2023-02-15
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7CHZ
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BU of 7chz by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A
分子名称: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26A, light chain of antibody binding fragment of IgG26A
著者Lee, C.C, Wang, A.H.J, Kuo, W.C.
登録日2020-07-06
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
7CHY
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BU of 7chy by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
分子名称: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26, light chain of antibody binding fragment of IgG26
著者Lee, C.C, Wang, A.H.J, Kuo, W.C.
登録日2020-07-06
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
6K1S
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BU of 6k1s by Molmil
Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase (PRMT5) Inhibitors
分子名称: 1,2-ETHANEDIOL, 2-[[7-[(2~{R},3~{R},4~{S},5~{R})-5-[(~{R})-(4-chlorophenyl)-oxidanyl-methyl]-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidin-4-yl]amino]ethanal, DIMETHYL SULFOXIDE, ...
著者Tong, S, Lin, H.
登録日2019-05-12
公開日2019-06-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors.
Acs Med.Chem.Lett., 10, 2019
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