4BPK
 
 | | Bcl-xL bound to alpha beta Puma BH3 peptide 5 | | 分子名称: | 1,2-ETHANEDIOL, ALPHA BETA BH3-PEPTIDE, BCL-2-LIKE PROTEIN 1, ... | | 著者 | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | 登録日 | 2013-05-27 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.756 Å) | | 主引用文献 | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
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4A1W
 | | Crystal structure of alpha-beta foldamer 4c in complex with Bcl-xL | | 分子名称: | ALPHA-BETA-FOLDAMER 2C, BCL-2-LIKE PROTEIN 1 | | 著者 | Boersma, M.D, Haase, H.S, Kaufman, K.J, Horne, W.S, Lee, E.F, Clarke, O.B, Smith, B.J, Colman, P.M, Gellman, S.H, Fairlie, W.D. | | 登録日 | 2011-09-20 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | | 主引用文献 | Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.
J.Am.Chem.Soc., 134, 2012
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4A1U
 | | Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL | | 分子名称: | ALPHA-BETA-FOLDAMER 2C, BCL-2-LIKE PROTEIN 1, CHLORIDE ION, ... | | 著者 | Boersma, M.D, Haase, H.S, Kaufman, K.J, Horne, W.S, Lee, E.F, Clarke, O.B, Smith, B.J, Colman, P.M, Gellman, S.H, Fairlie, W.D. | | 登録日 | 2011-09-20 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.
J.Am.Chem.Soc., 134, 2012
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4GWT
 | | Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. | | 登録日 | 2012-09-03 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
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4DZU
 | | Complex of 3-alpha bound to gp41-5 | | 分子名称: | 3-alpha, GLYCEROL, gp41-5 | | 著者 | Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H. | | 登録日 | 2012-03-01 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array.
J.Am.Chem.Soc., 134, 2012
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4DZV
 | | Complex of 4-alpha/beta bound to gp41-5 | | 分子名称: | 4-alpha/beta, GLYCEROL, gp41-5 | | 著者 | Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H. | | 登録日 | 2012-03-01 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array.
J.Am.Chem.Soc., 134, 2012
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4GWV
 | | Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate | | 分子名称: | CITRATE ANION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. | | 登録日 | 2012-09-03 | | 公開日 | 2013-10-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
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4HJD
 | | GCN4pLI derivative with alpha/beta/acyclic-gamma amino acid substitution pattern | | 分子名称: | GCN4pLI(alpha/beta/acyclic gamma) | | 著者 | Shin, Y.H, Mortenson, D.E, Satyshur, K.A, Forest, K.T, Gellman, S.H. | | 登録日 | 2012-10-12 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water.
J.Am.Chem.Soc., 135, 2013
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4HJB
 | | GCN4pLI derivative with alpha/beta/cyclic-gamma amino acid substitution pattern | | 分子名称: | GCN4pLI(alpha/beta/cyclic-gamma) | | 著者 | Shin, Y.H, Mortenson, D.E, Satyshur, K.A, Forest, K.T, Gellman, S.H. | | 登録日 | 2012-10-12 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water.
J.Am.Chem.Soc., 135, 2013
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2N6H
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2N6I
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2OXJ
 | | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-p1 with beta-residues at b and f heptad positions. | | 分子名称: | ACETATE ION, hybrid alpha/beta peptide based on the GCN4-p1 sequence; heptad positions b and f substituted with beta-amino acids | | 著者 | Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H. | | 登録日 | 2007-02-20 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
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2OXK
 | | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-pLI with beta-residues at b and f heptad positions. | | 分子名称: | FORMIC ACID, hybrid alpha/beta peptide based on the GCN4-pLI sequence; heptad positions b and f substituted with beta-amino acids | | 著者 | Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H. | | 登録日 | 2007-02-20 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
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2N4N
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3O43
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3O40
 | | Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 | | 分子名称: | CHLORIDE ION, GLYCEROL, NONAETHYLENE GLYCOL, ... | | 著者 | Horne, W.S, Johnson, L.M, Gellman, S.H. | | 登録日 | 2010-07-26 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
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3O42
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3O3Z
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3O3X
 | | Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, gp41-5 | | 著者 | Horne, W.S, Johnson, L.M, Gellman, S.H. | | 登録日 | 2010-07-26 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
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6MPL
 | | Racemic M2-TM I39A crystallized from racemic detergent | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-10-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
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6MPN
 | | Racemic M2-TM I42E crystallized from racemic detergent | | 分子名称: | Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-10-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
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6MPM
 | | Racemic M2-TM I42A crystallized from racemic detergent | | 分子名称: | Matrix protein 2, octyl beta-D-glucopyranoside | | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-10-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
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6NIV
 | | Racemic Phenol-Soluble Modulin Alpha 3 Peptide | | 分子名称: | Phenol-soluble modulin PSM-alpha-3 | | 著者 | Yao, Z, Cary, B.P, Bingman, C.A, Wang, C, Kreitler, D.F, Satyshur, K.A, Forest, K.T, Gellman, S.H. | | 登録日 | 2018-12-31 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin alpha 3 Toxicity.
J.Am.Chem.Soc., 141, 2019
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6NTX
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6NRO
 | | Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Human parainfluenza virus type 3 fusion glycoprotein C-terminal heptad repeat domain, ... | | 著者 | Outlaw, V.K, Kreitler, D.F, Gellman, S.H. | | 登録日 | 2019-01-23 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent.
J.Am.Chem.Soc., 141, 2019
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