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4EEF
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BU of 4eef by Molmil
Crystal structure of the designed inhibitor protein F-HB80.4 in complex with the 1918 influenza virus hemagglutinin.
分子名称: F-HB80.4, DESIGNED HEMAGGLUTININ BINDING PROTEIN, Hemagglutinin HA1 chain, ...
著者Dreyfus, C, Wilson, I.A.
登録日2012-03-28
公開日2012-06-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing.
Nat.Biotechnol., 30, 2012
7PVD
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BU of 7pvd by Molmil
Structure of the membrane soluble spike complex from the Lassa virus in a C1-symmetric map focused on the ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G2, ...
著者Diskin, R, Katz, M.
登録日2021-10-02
公開日2021-12-29
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure and receptor recognition by the Lassa virus spike complex.
Nature, 603, 2022
7PUY
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BU of 7puy by Molmil
Structure of the membrane soluble spike complex from the Lassa virus in a C3-symmetric map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G2, ...
著者Diskin, R, Katz, M.
登録日2021-10-01
公開日2021-12-29
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and receptor recognition by the Lassa virus spike complex.
Nature, 603, 2022
8CY8
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BU of 8cy8 by Molmil
apo form Cryo-EM structure of Campylobacter jejune ketol-acid reductoisommerase crosslinked by Glutaraldehyde
分子名称: Ketol-acid reductoisomerase (NADP(+)), PENTANEDIAL
著者Zheng, S, Guddat, L.W.
登録日2022-05-23
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals
Appl Biosci, 2022
6WA0
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BU of 6wa0 by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
分子名称: De novo designed receptor transmembrane domain proMP C3.1
著者Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
登録日2020-03-24
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.484 Å)
主引用文献De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
6W9Y
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BU of 6w9y by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain proMP 1.2
著者Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
登録日2020-03-24
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
6W9Z
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BU of 6w9z by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain ProMP C2.1
著者Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
登録日2020-03-24
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
3U43
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BU of 3u43 by Molmil
Crystal structure of the colicin E2 DNase-Im2 complex
分子名称: CALCIUM ION, Colicin-E2, Colicin-E2 immunity protein, ...
著者Wojdyla, J.A, Kleanthous, C.
登録日2011-10-07
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structure of the Ultra-High-Affinity Colicin E2 DNase-Im2 Complex.
J.Mol.Biol., 417, 2012
3VB8
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BU of 3vb8 by Molmil
Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43
分子名称: Engineered protein, SULFATE ION
著者Seetharaman, J, Su, M, Procko, E, Baker, D, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2011-12-31
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Computational design of a protein-based enzyme inhibitor.
J.Mol.Biol., 425, 2013
6XUD
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BU of 6xud by Molmil
Apo Ab 1116NS19.9
分子名称: Heavy chain, Light chain
著者Diskin, R, Borenstein-Katz, A.
登録日2020-01-19
公開日2021-01-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6XUL
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BU of 6xul by Molmil
Apo Ab 5b1
分子名称: Heavy chain, Light chain
著者Diskin, R, Borenstein-Katz, A.
登録日2020-01-20
公開日2021-02-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6YBH
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BU of 6ybh by Molmil
Deoxyribonucleoside Kinase
分子名称: Deoxynucleoside kinase, GLYCEROL, Pyrrolo-dC, ...
著者Allouche-Arnon, H, Bar-Shir, A, Dym, O.
登録日2020-03-17
公開日2021-03-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.
Nat.Biotechnol., 40, 2022
6XUK
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BU of 6xuk by Molmil
AbLIFT design 15 of Ab 1116NS19.9
分子名称: GLYCEROL, Heavy chain, Light chain, ...
著者Diskin, R, Borenstein-Katz, A.
登録日2020-01-20
公開日2021-02-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
5D96
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BU of 5d96 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
分子名称: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
著者Fass, D, Grossman, I.
登録日2015-08-18
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D93
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BU of 5d93 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
分子名称: Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Sulfhydryl oxidase 1
著者Grossman, I, Fass, D.
登録日2015-08-18
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D8I
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BU of 5d8i by Molmil
Engineering the Species-Specificity of an Inhibitory Antibody Targeting a Modulator of Tumor Stroma
分子名称: Sulfhydryl oxidase 1
著者Grossman, I, Fass, D.
登録日2015-08-17
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
6GVS
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BU of 6gvs by Molmil
Engineered glycolyl-CoA reductase comprising 8 mutations with bound NADP+
分子名称: Aldehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION
著者Zarzycki, J, Trudeau, D, Scheffen, M, Erb, T.J, Tawfik, D.S.
登録日2018-06-21
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.579 Å)
主引用文献Design and in vitro realization of carbon-conserving photorespiration.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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