7XW7
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![BU of 7xw7 by Molmil](/molmil-images/mine/7xw7) | TSHR-K1-70 complex | 分子名称: | K1-70 scFv, Thyrotropin receptor | 著者 | Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. | 登録日 | 2022-05-26 | 公開日 | 2022-08-17 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
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7XW5
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![BU of 7xw5 by Molmil](/molmil-images/mine/7xw5) | TSHR-thyroid stimulating hormone-Gs-ML109 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Glycoprotein hormones alpha chain, ... | 著者 | Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. | 登録日 | 2022-05-26 | 公開日 | 2022-08-24 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
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7XW6
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![BU of 7xw6 by Molmil](/molmil-images/mine/7xw6) | TSHR-Gs-M22 antibody-ML109 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. | 登録日 | 2022-05-26 | 公開日 | 2022-08-17 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
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8I2H
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![BU of 8i2h by Molmil](/molmil-images/mine/8i2h) | Follicle stimulating hormone receptor | 分子名称: | Follicle-stimulating hormone receptor | 著者 | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | 登録日 | 2023-01-14 | 公開日 | 2023-03-22 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
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8I2G
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![BU of 8i2g by Molmil](/molmil-images/mine/8i2g) | FSHR-Follicle stimulating hormone-compound 716340-Gs complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | 登録日 | 2023-01-14 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
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8PVM
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![BU of 8pvm by Molmil](/molmil-images/mine/8pvm) | formaldehyde-inhibited [FeFe]-hydrogenase CpI from Clostridium pasteurianum, variant C299D | 分子名称: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, FORMYL GROUP, ... | 著者 | Duan, J, Hofmann, E, Happe, T. | 登録日 | 2023-07-18 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Insights into the Molecular Mechanism of Formaldehyde Inhibition of [FeFe]-Hydrogenases. J.Am.Chem.Soc., 145, 2023
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8QM3
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7WQ4
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![BU of 7wq4 by Molmil](/molmil-images/mine/7wq4) | Galanin-bound galanin receptor 2 in complex with Gq | 分子名称: | CHOLESTEROL, Engineered Guanine nucleotide-binding protein G(q) subunit alpha, Galanin, ... | 著者 | Duan, J, Shen, D.D, Xu, H.E, Zhang, Y, Jiang, Y. | 登録日 | 2022-01-24 | 公開日 | 2022-04-20 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors Nat Commun, 13, 2022
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7WQ3
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![BU of 7wq3 by Molmil](/molmil-images/mine/7wq3) | Galanin-bound galanin receptor 1 in complex with Gi | 分子名称: | CHOLESTEROL, Galanin, Galanin receptor type 1, ... | 著者 | Duan, J, Shen, D.D, Xu, H.E, Zhang, Y, Jiang, Y. | 登録日 | 2022-01-24 | 公開日 | 2022-04-20 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors Nat Commun, 13, 2022
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7FIJ
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![BU of 7fij by Molmil](/molmil-images/mine/7fij) | luteinizing hormone/choriogonadotropin receptor | 分子名称: | Lutropin-choriogonadotropic hormone receptor | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | 登録日 | 2021-07-31 | 公開日 | 2021-09-29 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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7FIH
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![BU of 7fih by Molmil](/molmil-images/mine/7fih) | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex | 分子名称: | 5-azanyl-N-tert-butyl-2-methylsulfanyl-4-[3-(2-morpholin-4-ylethanoylamino)phenyl]thieno[2,3-d]pyrimidine-6-carboxamide, Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, ... | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | 登録日 | 2021-07-31 | 公開日 | 2021-09-29 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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7FII
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![BU of 7fii by Molmil](/molmil-images/mine/7fii) | luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex | 分子名称: | Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, Glycoprotein hormones alpha chain, ... | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | 登録日 | 2021-07-31 | 公開日 | 2021-09-29 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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7FIG
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![BU of 7fig by Molmil](/molmil-images/mine/7fig) | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid antibody VHH fragment Nb35, Choriogonadotropin subunit beta 3, ... | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | 登録日 | 2021-07-31 | 公開日 | 2021-09-29 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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6YF4
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![BU of 6yf4 by Molmil](/molmil-images/mine/6yf4) | [FeFe]-hydrogenase I from Clostridium pasteurianum (CpI), variant E279D | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, Iron hydrogenase 1, ... | 著者 | Duan, J, Hofmann, E, Happe, T. | 登録日 | 2020-03-25 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | The roles of long-range proton-coupled electron transfer in the directionality and efficiency of [FeFe]-hydrogenases. Proc.Natl.Acad.Sci.USA, 117, 2020
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5LA3
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![BU of 5la3 by Molmil](/molmil-images/mine/5la3) | [FeFe]-hydrogenase CpI from Clostridium pasteurianum, variant E279A | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, Iron hydrogenase 1, ... | 著者 | Duan, J, Esselborn, J, Hofmann, E, Winkler, M, Happe, T. | 登録日 | 2016-06-13 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Accumulating the hydride state in the catalytic cycle of [FeFe]-hydrogenases. Nat Commun, 8, 2017
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6TTL
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![BU of 6ttl by Molmil](/molmil-images/mine/6ttl) | crystal structure of [FeFe]-hydrogenase CbA5H (partial) from Clostridium beijerinckii in Hinact state | 分子名称: | IRON/SULFUR CLUSTER, [FeFe]-hydrogenase, dicarbonyl[bis(cyanide-kappaC)]-mu-(iminodimethanethiolatato-1kappaS:2kappaS)-mu-(oxomethylidene)diiron(2+) | 著者 | Duan, J, Rutz, A, Hofmann, E, Happe, T. | 登録日 | 2019-12-28 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A safety cap protects hydrogenase from oxygen attack. Nat Commun, 12, 2021
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5ZX5
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![BU of 5zx5 by Molmil](/molmil-images/mine/5zx5) | 3.3 angstrom structure of mouse TRPM7 with EDTA | 分子名称: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 7 | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E. | 登録日 | 2018-05-18 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BWI
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![BU of 6bwi by Molmil](/molmil-images/mine/6bwi) | 3.7 angstrom cryoEM structure of full length human TRPM4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Clapham, D.E. | 登録日 | 2017-12-15 | 公開日 | 2018-12-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of full-length human TRPM4. Proc.Natl.Acad.Sci.USA, 115, 2018
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6BWD
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![BU of 6bwd by Molmil](/molmil-images/mine/6bwd) | 3.7 angstrom cryoEM structure of truncated mouse TRPM7 | 分子名称: | CHOLESTEROL HEMISUCCINATE, MAGNESIUM ION, Transient receptor potential cation channel subfamily M member 7 | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E. | 登録日 | 2017-12-14 | 公開日 | 2018-08-15 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BWF
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![BU of 6bwf by Molmil](/molmil-images/mine/6bwf) | 4.1 angstrom Mg2+-unbound structure of mouse TRPM7 | 分子名称: | TRPM7 | 著者 | Zhang, J, Li, Z, Duan, J, Abiria, S.A, Clapham, D.E. | 登録日 | 2017-12-14 | 公開日 | 2018-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8H8J
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![BU of 8h8j by Molmil](/molmil-images/mine/8h8j) | Lodoxamide-bound GPR35 in complex with G13 | 分子名称: | 2,2'-[(2-chloro-5-cyano-1,3-phenylene)bis(azanediyl)]bis(oxoacetic acid), CALCIUM ION, CHOLESTEROL, ... | 著者 | Yuan, Q, Duan, J, Liu, Q, Xu, H.E, Jiang, Y. | 登録日 | 2022-10-23 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35. Cell Discov, 8, 2022
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9IJA
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![BU of 9ija by Molmil](/molmil-images/mine/9ija) | A local Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex | 分子名称: | 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine, CHOLESTEROL, Taste receptor type 2 member 14 | 著者 | Yuan, Q, Duan, J, Tao, L, Xu, E.H. | 登録日 | 2024-06-21 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist. Cell Res., 2024
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9IIW
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9IIX
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![BU of 9iix by Molmil](/molmil-images/mine/9iix) | A Cryo-EM structure of Bitter taste receptor TAS2R14 with Ggust | 分子名称: | 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yuan, Q, Duan, J, Tao, L, Xu, E.H. | 登録日 | 2024-06-21 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist. Cell Res., 2024
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9IJ9
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![BU of 9ij9 by Molmil](/molmil-images/mine/9ij9) | A Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex | 分子名称: | 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Yuan, Q, Duan, J, Tao, L, Xu, E.H. | 登録日 | 2024-06-21 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist. Cell Res., 2024
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