8IEX
 
 | | Solution structure of AtWRKY11-DBD | | 分子名称: | Probable WRKY transcription factor 11, ZINC ION | | 著者 | Dong, X, Hu, Y.F. | | 登録日 | 2023-02-16 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the DNA binding domain of Arabidopsis transcription factor WRKY11.
Biochem.Biophys.Res.Commun., 653, 2023
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2L22
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7LMX
 | | A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE | | 分子名称: | Integrin inhibitor | | 著者 | Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. | | 登録日 | 2021-02-06 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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7LMV
 | | SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 | | 分子名称: | Integrin inhibitor | | 著者 | Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. | | 登録日 | 2021-02-05 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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5VBT
 | | Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor | | 分子名称: | UBH04 | | 著者 | DONG, A, DONG, X, LIU, L, GUO, Y, LI, Y, ZHANG, W, WALKER, J.R, SIDHU, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-30 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
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5YZ9
 | | zinc finger domain of METTL3-METTL14 N6-methyladenosine methyltransferase | | 分子名称: | N6-adenosine-methyltransferase catalytic subunit, ZINC ION | | 著者 | Dong, X, Tang, C, Gong, Z, Yin, P, Huang, J.B. | | 登録日 | 2017-12-13 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | | 主引用文献 | Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
Protein Cell, 10, 2019
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8IVB
 | | K113-Ubiquitinated BAK | | 分子名称: | Bcl-2 homologous antagonist/killer, Ubiquitin | | 著者 | Dong, X, Cheng, P, Hou, Y.Z, Chen, Y.K, Liu, Z. | | 登録日 | 2023-03-26 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove.
Commun Biol, 6, 2023
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6KOX
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3JXE
 | | Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase in complex with TrpAMP | | 分子名称: | SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | 著者 | Zhou, M, Dong, X, Zhong, C, Shen, N, Yang, B, Ding, J. | | 登録日 | 2009-09-19 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of P. horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
To be Published
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5XBO
 | | Lanthanoid tagging via an unnatural amino acid for protein structure characterization | | 分子名称: | Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A | | 著者 | Jiang, W, Gu, X, Dong, X, Tang, C. | | 登録日 | 2017-03-21 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lanthanoid tagging via an unnatural amino acid for protein structure characterization
J. Biomol. NMR, 67, 2017
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4C29
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | | 登録日 | 2013-08-16 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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4C2A
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with R1306Q and I1309V Mutations in Complex with High Affinity GPIb alpha | | 分子名称: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | | 登録日 | 2013-08-16 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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4C2B
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | | 登録日 | 2013-08-16 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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7F7X
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8ZU0
 | | CryoEM structure of a tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG | | 著者 | Jiang, W.X, Cheng, X.Q, Dong, X, Ma, L.X, Xing, Q. | | 登録日 | 2024-06-07 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | CryoEM structure of a tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA
To Be Published
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6WPG
 | | Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins | | 分子名称: | 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4 | | 著者 | Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N. | | 登録日 | 2020-04-27 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.283 Å) | | 主引用文献 | Structural basis of salicylic acid perception by Arabidopsis NPR proteins.
Nature, 586, 2020
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7TAD
 | | CryoEM structure of the (NPR1)2-(TGA3)2 complex | | 分子名称: | PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... | | 著者 | Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. | | 登録日 | 2021-12-20 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
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7TAC
 | | Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex | | 分子名称: | PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... | | 著者 | Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. | | 登録日 | 2021-12-20 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
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9JAQ
 | | Cryo-EM structure of MPXV core protease in the apo-form | | 分子名称: | Core protease I7 | | 著者 | Lan, W, You, T, Li, D, Dong, X, Wang, H, Xu, J, Wang, W, Gao, Y, Yang, H. | | 登録日 | 2024-08-25 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 2025
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9KQV
 | | Cryo-EM structure of MPXV core protease in complex with aloxistatin(E64d) | | 分子名称: | Core protease I7, ethyl (3S)-3-hydroxy-4-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}amino)-4-oxobutanoate | | 著者 | Lan, W, You, T, Li, D, Dong, X, Wang, H, Xu, J, Wang, W, Gao, Y, Yang, H. | | 登録日 | 2024-11-27 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 2025
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9KR6
 | | Cryo-EM structure of MPXV core protease in complex with the substrate derivative I-G18 | | 分子名称: | Core protease I7, Core protein VP8 | | 著者 | Lan, W, You, T, Li, D, Dong, X, Wang, H, Xu, J, Wang, W, Gao, Y, Yang, H. | | 登録日 | 2024-11-27 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 2025
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3PPY
 | | Crystal structure of the D1596A/N1602A double mutant of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | SODIUM ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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3PPV
 | | Crystal structure of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | CALCIUM ION, SULFATE ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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3PPW
 | | Crystal structure of the D1596A mutant of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | SODIUM ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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3PPX
 | | Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | SODIUM ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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