8IVB

K113-Ubiquitinated BAK

Summary for 8IVB

• Entry DOI: 10.2210/pdb8ivb/pdb
• Descriptor: Ubiquitin, Bcl-2 homologous antagonist/killer (2 entities in total)
• Functional Keywords: pro-apoptotic bcl-2 proteins, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 27547.13

Authors

Dong, X.,Cheng, P.,Hou, Y.Z.,Chen, Y.K.,Liu, Z. (deposition date: 2023-03-26, release date: 2024-01-31, Last modification date: 2024-05-15)

• Primary citation: Cheng, P.,Hou, Y.,Bian, M.,Fang, X.,Liu, Y.,Rao, Y.,Cao, S.,Liu, Y.,Zhang, S.,Chen, Y.,Dong, X.,Liu, Z.; Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove.; Commun Biol, 6:1260-1260, 2023; PubMed: 38087033; DOI: 10.1038/s42003-023-05650-z

Experimental method

SOLUTION NMR