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1JAW
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BU of 1jaw by Molmil
AMINOPEPTIDASE P FROM E. COLI LOW PH FORM
分子名称: ACETATE ION, AMINOPEPTIDASE P, MANGANESE (II) ION
著者Wilce, M.C.J, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M.
登録日1997-12-22
公開日1999-04-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 95, 1998
1JWE
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BU of 1jwe by Molmil
NMR Structure of the N-Terminal Domain of E. Coli Dnab Helicase
分子名称: PROTEIN (DNAB HELICASE)
著者Weigelt, J, Brown, S.E, Miles, C.S, Dixon, N.E, Otting, G.
登録日1999-01-22
公開日1999-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer.
Structure Fold.Des., 7, 1999
2AXD
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BU of 2axd by Molmil
solution structure of the theta subunit of escherichia coli DNA polymerase III in complex with the epsilon subunit
分子名称: DNA polymerase III, theta subunit
著者Keniry, M.A, Park, A.Y, Owen, E.A, Hamdan, S.M, Pintacuda, G, Otting, G, Dixon, N.E.
登録日2005-09-05
公開日2006-07-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit
J.Bacteriol., 188, 2006
2AYA
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BU of 2aya by Molmil
Solution Structure of the C-Terminal 14 kDa Domain of the tau subunit from Escherichia coli DNA Polymerase III
分子名称: DNA polymerase III subunit tau
著者Jergic, S, Dixon, N.E, Otting, G, Su, X.C.
登録日2005-09-07
公開日2006-11-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit.
Nucleic Acids Res., 35, 2007
2PII
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BU of 2pii by Molmil
PII, GLNB PRODUCT
分子名称: PII
著者Carr, P.D, Cheah, E, Suffolk, P.M, Ollis, D.L.
登録日1995-05-02
公開日1996-06-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structure of the signal transduction protein from Escherichia coli at 1.9 A.
Acta Crystallogr.,Sect.D, 52, 1996
1PIL
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BU of 1pil by Molmil
STRUCTURE OF THE ESCHERICHIA COLI SIGNAL TRANSDUCING PROTEIN PII
分子名称: SIGNAL TRANSDUCING PROTEIN P2
著者Ollis, D.L, Cheah, U.E, Carr, P.D, Suffolk, P.M.
登録日1994-08-04
公開日1995-08-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Escherichia coli signal transducing protein PII.
Structure, 2, 1994
3X1O
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BU of 3x1o by Molmil
Crystal structure of the ROQ domain of human Roquin
分子名称: IODIDE ION, Roquin-1
著者Ose, T, Verma, A, Cockburn, J.B, Berrow, N.S, Alderton, D, Stuart, D, Owens, R.J, Jones, E.Y.
登録日2014-11-26
公開日2015-03-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis
Nat Commun, 6, 2015
6AMS
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BU of 6ams by Molmil
Crystal structure of the DNA polymerase III subunit beta from Pseudomonas aeruginosa
分子名称: Beta sliding clamp, PHOSPHATE ION
著者McGrath, A.E, Oakley, A.J.
登録日2017-08-11
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens.
J. Struct. Biol., 204, 2018
6AMQ
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BU of 6amq by Molmil
Crystal structure of the DNA polymerase III subunit beta from Enterobacter cloacae
分子名称: DNA polymerase III subunit beta, SULFATE ION
著者McGrath, A.E, Oakley, A.J.
登録日2017-08-11
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens.
J. Struct. Biol., 204, 2018
6AP4
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BU of 6ap4 by Molmil
Crystal structure of the DNA polymerase III subunit beta from Acinetobacter baumannii
分子名称: DNA polymerase III subunit beta, MAGNESIUM ION
著者McGrath, A.E, Oakley, A.J.
登録日2017-08-16
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens.
J. Struct. Biol., 204, 2018
4XR0
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BU of 4xr0 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- G/T mismatch.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3'), ...
著者Oakley, A.J.
登録日2015-01-20
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
4XR1
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BU of 4xr1 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- AG/AT mismatch.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*TP*AP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*G)-3'), ...
著者Oakley, A.J.
登録日2015-01-20
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
4XR3
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BU of 4xr3 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- GC(6) swapped.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*TP*AP*CP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*GP*T)-3'), ...
著者Oakley, A.J.
登録日2015-01-20
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
4XR2
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BU of 4xr2 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) H114A mutant Complexed With DNA- TerA lock.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*C)-3'), ...
著者Oakley, A.J.
登録日2015-01-20
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
2NUL
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BU of 2nul by Molmil
PEPTIDYLPROLYL ISOMERASE FROM E. COLI
分子名称: PEPTIDYLPROLYL ISOMERASE
著者Edwards, K.J, Ollis, D.L.
登録日1996-11-14
公開日1997-11-19
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of cytoplasmic Escherichia coli peptidyl-prolyl isomerase: evidence for decreased mobility of loops upon complexation.
J.Mol.Biol., 271, 1997
6CIX
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BU of 6cix by Molmil
Lactam cyclised mimetic of a fragment of p21
分子名称: p21
著者Wegener, K.L.
登録日2018-02-25
公開日2018-07-04
最終更新日2024-11-20
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CEJ
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BU of 6cej by Molmil
Solution structure of a 14mer fragment of the p21 protein
分子名称: Cyclin-dependent kinase inhibitor 1
著者Wegener, K.L.
登録日2018-02-12
公開日2018-07-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
7SSG
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BU of 7ssg by Molmil
Mfd DNA complex
分子名称: DNA (5'-D(P*TP*GP*GP*CP*GP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*GP*CP*CP*TP*CP*GP*CP*TP*GP*CP*CP*A)-3'), Transcription-repair-coupling factor
著者Oakley, A.J, Xu, Z.-Q.
登録日2021-11-11
公開日2022-05-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Mechanism of transcription modulation by the transcription-repair coupling factor.
Nucleic Acids Res., 50, 2022
6CBI
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BU of 6cbi by Molmil
PCNA in complex with inhibitor
分子名称: GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION
著者Bruning, J.B, Wegener, K.L.
登録日2018-02-03
公開日2018-07-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CIV
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BU of 6civ by Molmil
Lactam cyclised mimetic of a fragment of p21
分子名称: p21
著者Wegener, K.L.
登録日2018-02-25
公開日2018-07-04
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
4MJR
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BU of 4mjr by Molmil
E. coli sliding clamp in complex with (S)-Carprofen
分子名称: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-09-04
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJP
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BU of 4mjp by Molmil
E. coli sliding clamp in complex with (R)-Vedaprofen
分子名称: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-09-04
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.855 Å)
主引用文献DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJQ
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E. coli sliding clamp in complex with Bromfenac
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-09-04
公開日2013-09-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4N96
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E. coli sliding clamp in complex with 6-nitroindazole
分子名称: 6-NITROINDAZOLE, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-10-19
公開日2013-11-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014
4N95
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E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione
分子名称: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-10-19
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57, 2014

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