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Structure of E.Coli GlpG complexed with peptidic inhibitor Ac-VRMA-CHO
分子名称:	Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
著者	Urban, S, Cho, S, Dickey, S.W.
登録日	2015-12-04
公開日	2016-02-17
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5G

Structure of E.Coli GlpG Y205F mutant complexed with peptidic inhibitor Ac-RMA-CHO in the DMPC/CHAPSO bicelle
分子名称:	ACE-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
著者	Urban, S, Cho, S, Dickey, S.W.
登録日	2015-12-04
公開日	2016-04-06
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

6PJU

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-11-27
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJR

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	CHLORIDE ION, Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-10-02
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJA

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-10-02
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ5

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-27
公開日	2019-10-02
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ9

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-10-02
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ7

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-10-02
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJQ

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-11-27
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ8

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-10-02
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJP

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-28
公開日	2019-10-02
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.45 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ4

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者	Urban, S, Cho, S.
登録日	2019-06-27
公開日	2019-10-02
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

5F5J

E.coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
分子名称:	Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
著者	Urban, S, Cho, S, Dickey, S.
登録日	2015-12-04
公開日	2016-02-10
最終更新日	2016-02-17
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5D

Crystal structures and Inhibition kinetics reveal a two-state catalytic mechanism with drug design implications for rhomboid proteolysis
分子名称:	Rhomboid protease GlpG
著者	Urban, S, Cho, S, Dickey, S.W.
登録日	2015-12-04
公開日	2016-02-24
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5K

E.Coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
分子名称:	Peptidic derivative of Gurken: ACE-ARG-LYS-VAL-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
著者	Urban, S, Cho, S, Dickey, S.W.
登録日	2015-12-04
公開日	2016-02-10
最終更新日	2016-02-17
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

3G8K

Crystal structure of murine natural killer cell receptor, Ly49L4
分子名称:	Lectin-related NK cell receptor LY49L1
著者	Cho, S.
登録日	2009-02-12
公開日	2009-11-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity, 31, 2009

3G8L

Crystal structure of murine natural killer cell receptor, Ly49L4
分子名称:	Lectin-related NK cell receptor LY49L1
著者	Cho, S.
登録日	2009-02-12
公開日	2009-11-17
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity, 31, 2009

4Z1B

Structure of H204A mutant KDO8PS from H.pylori
分子名称:	2-dehydro-3-deoxyphosphooctonate aldolase
著者	Lee, B.J, Cho, S, Im, H, Yoon, H.J.
登録日	2015-03-27
公開日	2016-03-09
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016

4Z1C

Structure of Cadmium bound KDO8PS from H.pylori
分子名称:	2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION
著者	Lee, B.J, Cho, S, Im, H, Yoon, H.J.
登録日	2015-03-27
公開日	2016-03-09
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (1.93 Å)
主引用文献	Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016

4Z1A

Structure of apo form KDO8PS from H.pylori
分子名称:	2-dehydro-3-deoxyphosphooctonate aldolase
著者	Lee, B.J, Cho, S, Im, H, Yoon, H.J.
登録日	2015-03-27
公開日	2016-03-09
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016

4Z1D

Structure of PEP and zinc bound KDO8PS from H.pylori
分子名称:	2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHOENOLPYRUVATE, ZINC ION
著者	Lee, B.J, Cho, S, Im, H, Yoon, H.J.
登録日	2015-03-27
公開日	2016-03-09
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016

6XRP

Crystal structure of GlpG in complex with peptide ketoamide inhibitor, Ac-RVWHA-ketoamide-phenylbutyl
分子名称:	N-(4-phenylbutyl)formamide, Rhomboid protease GlpG, peptide ketoamide inhibitor
著者	Urban, S, Cho, S.
登録日	2020-07-13
公開日	2020-09-16
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

4NJN

Crystal Structure of E.coli GlpG at pH 4.5
分子名称:	Rhomboid protease GlpG
著者	Dickey, S.W, Baker, R.P, Cho, S, Urban, S.
登録日	2013-11-11
公開日	2013-12-25
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell(Cambridge,Mass.), 155, 2013

6XRO

Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2
分子名称:	CHLORIDE ION, Rhomboid protease GlpG, SODIUM ION, ...
著者	Urban, S, Cho, S.
登録日	2020-07-13
公開日	2020-09-16
最終更新日	2024-04-24
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

6VJ8

Crystal structure of GlpG in complex with peptide chloromethylketone inhibitor
分子名称:	Peptide chloromethylketone inhibitor, Rhomboid family intramembrane serine protease GlpG
著者	Urban, S, Cho, S.
登録日	2020-01-15
公開日	2020-09-16
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

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