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5ESV
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BU of 5esv by Molmil
Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256.
分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Yang, M, Kwong, P.D.
登録日2015-11-17
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat.Struct.Mol.Biol., 23, 2016
5ESZ
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BU of 5esz by Molmil
Crystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade AE Strain A244
分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH04 Heavy Chain, ...
著者Gorman, J, Yang, M, Kwong, P.D.
登録日2015-11-17
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.191 Å)
主引用文献Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat. Struct. Mol. Biol., 23, 2016
6MNR
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BU of 6mnr by Molmil
Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide
分子名称: 1,2-ETHANEDIOL, Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, ...
著者Nicely, N.I.
登録日2018-10-02
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nat Commun, 10, 2019
6MNQ
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BU of 6mnq by Molmil
Rhesus macaque anti-HIV V3 antibody DH727.2 with gp120 V3 ZAM18 peptide
分子名称: 1,2-ETHANEDIOL, Ab DH727.2 heavy chain Fab fragment, Ab DH727.2 light chain, ...
著者Nicely, N.I.
登録日2018-10-02
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.804 Å)
主引用文献Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nat Commun, 10, 2019
6MNS
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BU of 6mns by Molmil
Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide
分子名称: Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, Envelope glylcoprotein, ...
著者Nicely, N.I.
登録日2018-10-02
公開日2019-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nat Commun, 10, 2019
4FZ8
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BU of 4fz8 by Molmil
Crystal structure of C11 Fab, an ADCC mediating anti-HIV-1 antibody.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB heavy chain of human ANTI-HIV-1 ENV ANTIBODY C11, FAB light chain of human ANTI-HIV-1 ENV ANTIBODY C11, ...
著者Wu, X, Tolbert, W.D, Pazgier, M.
登録日2012-07-06
公開日2013-07-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
Mbio, 11, 2020
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
分子名称: CH58 Fab heavy chain, CH58 Fab light chain
著者McLellan, J.S, Haynes, B.F, Kwong, P.D.
登録日2012-10-25
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPY
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BU of 4hpy by Molmil
Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide
分子名称: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
著者McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日2012-10-24
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPO
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BU of 4hpo by Molmil
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
分子名称: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
著者McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日2012-10-24
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.694 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
6VTU
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BU of 6vtu by Molmil
DH717.1 Fab monomer in complex with man9 glycan
分子名称: DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ...
著者Fera, D, Bronkema, N.
登録日2020-02-13
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L02
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BU of 7l02 by Molmil
Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者Manne, K, Henderson, R, Acharya, P.
登録日2020-12-10
公開日2020-12-30
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L09
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BU of 7l09 by Molmil
Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者Manne, K, Henderson, R, Acharya, P.
登録日2020-12-11
公開日2020-12-30
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L6O
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BU of 7l6o by Molmil
Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ...
著者Manne, K, Edwards, R.J, Acharya, P.
登録日2020-12-23
公開日2021-04-14
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7LUA
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BU of 7lua by Molmil
Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 SOSIP gp120, ...
著者Manne, K, Edwards, R.J, Acharya, P.
登録日2021-02-21
公開日2021-03-17
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7LU9
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BU of 7lu9 by Molmil
Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Manne, K, Edwards, R.J, Acharya, P.
登録日2021-02-21
公開日2021-03-24
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L06
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BU of 7l06 by Molmil
Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者Manne, K, Henderson, R, Acharya, P.
登録日2020-12-11
公開日2020-12-30
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L6M
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BU of 7l6m by Molmil
Cryo-EM structure of DH898.1 Fab-dimer from local refinement of the Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
分子名称: DH898.1 Fab heavy chain, DH898.1 Fab light chain
著者Manne, K, Edwards, R.J, Acharya, P.
登録日2020-12-23
公開日2021-02-10
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
6VBQ
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BU of 6vbq by Molmil
Crystal structure of anti-HIV-1 antibody DH822 bound to gp120 V2 peptide
分子名称: DH822 heavy chain, DH822 light chain, Envelope glycoprotein gp160
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.116 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020
6VBO
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BU of 6vbo by Molmil
Crystal structure of anti-HIV-1 antibody DH813 bound to gp120 V2 peptide
分子名称: DH813 heavy chain, DH813 light chain, Envelope glycoprotein gp160
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.683 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020
6VBP
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BU of 6vbp by Molmil
Crystal structure of anti-HIV-1 antibody DH815 bound to gp120 V2 peptide
分子名称: CHLORIDE ION, DH815 heavy chain, DH815 light chain, ...
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020
6UM5
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BU of 6um5 by Molmil
Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Acharya, P, Henderson, R.C, Saunders, K.O, Haynes, B.F.
登録日2019-10-09
公開日2019-12-18
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
4LSS
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BU of 4lss by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER_2018_11 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY VRC01, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
6UM6
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BU of 6um6 by Molmil
Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Acharya, P, Henderson, R.C, Saunder, K.O, Haynes, B.F.
登録日2019-10-09
公開日2019-12-18
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
4LST
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BU of 4lst by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade C strain ZM176.66 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, HEAVY CHAIN OF ANTIBODY VRC01, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSU
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BU of 4lsu by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013

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