1SGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sgg by Molmil](/molmil-images/mine/1sgg) | THE SOLUTION STRUCTURE OF SAM DOMAIN FROM THE RECEPTOR TYROSINE KINASE EPHB2, NMR, 10 STRUCTURES | 分子名称: | EPHRIN TYPE-B RECEPTOR 2 | 著者 | Smalla, M, Schmieder, P, Kelly, M, Ter Laak, A, Krause, G, Ball, L, Wahl, M, Bork, P, Oschkinat, H. | 登録日 | 1999-01-08 | 公開日 | 1999-10-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites. Protein Sci., 8, 1999
|
|
4BBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bbq by Molmil](/molmil-images/mine/4bbq) | Crystal structure of the CXXC and PHD domain of Human Lysine-specific Demethylase 2A (KDM2A)(FBXL11) | 分子名称: | 1,2-ETHANEDIOL, LYSINE-SPECIFIC DEMETHYLASE 2A, ZINC ION | 著者 | Allerston, C.K, Watson, A.A, Edlich, C, Li, B, Chen, Y, Ball, L, Krojer, T, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Laue, E.D, Gileadi, O. | 登録日 | 2012-09-27 | 公開日 | 2012-10-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal Structure of the Cxxc and Phd Domain of Human Lysine-Specific Demethylase 2A (Kdm2A)(Fbxl11) To be Published
|
|
2C47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c47 by Molmil](/molmil-images/mine/2c47) | Structure of casein kinase 1 gamma 2 | 分子名称: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, CASEIN KINASE 1 GAMMA 2 ISOFORM, MAGNESIUM ION | 著者 | Bunkoczi, G, Rellos, P, Das, S, Ugochukwu, E, Fedorov, O, Sobott, F, Eswaran, J, Amos, A, Ball, L, von Delft, F, Bullock, A, Debreczeni, J, Turnbull, A, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | 登録日 | 2005-10-16 | 公開日 | 2005-11-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structure of Casein Kinase 1 Gamma 2 To be Published
|
|
2LG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lg1 by Molmil](/molmil-images/mine/2lg1) | |
6RN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rn1 by Molmil](/molmil-images/mine/6rn1) | Structure of N-terminal truncated Plasmodium falciparum IMP-nucleotidase | 分子名称: | IMP-specific 5'-nucleotidase, putative | 著者 | Carrique, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2019-05-07 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nat Commun, 11, 2020
|
|
6RNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rnh by Molmil](/molmil-images/mine/6rnh) | Structure of C-terminal truncated Plasmodium falciparum IMP-nucleotidase | 分子名称: | GLYCEROL, IMP-specific 5'-nucleotidase, putative | 著者 | Carrique, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2019-05-08 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nat Commun, 11, 2020
|
|
6RMW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rmw by Molmil](/molmil-images/mine/6rmw) | Structure of N-terminal truncated IMP bound Plasmodium falciparum IMP-nucleotidase | 分子名称: | GLYCEROL, IMP-specific 5'-nucleotidase, putative, ... | 著者 | Carrique, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2019-05-07 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nat Commun, 11, 2020
|
|
6RMO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rmo by Molmil](/molmil-images/mine/6rmo) | Structure of Plasmodium falciparum IMP-nucleotidase | 分子名称: | IMP-specific 5'-nucleotidase, putative | 著者 | Carrique, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2019-05-07 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nat Commun, 11, 2020
|
|
7QP1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qp1 by Molmil](/molmil-images/mine/7qp1) | Crystal structure of metacaspase from candida glabrata with calcium | 分子名称: | CALCIUM ION, CHLORIDE ION, Metacaspase-1 | 著者 | Conchou, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2021-12-30 | 公開日 | 2023-01-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium. Commun Biol, 5, 2022
|
|
7QP0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qp0 by Molmil](/molmil-images/mine/7qp0) | Crystal structure of metacaspase from candida glabrata with magnesium | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Metacaspase-1 | 著者 | Conchou, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2021-12-30 | 公開日 | 2023-01-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium. Commun Biol, 5, 2022
|
|
6RMD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rmd by Molmil](/molmil-images/mine/6rmd) | Structure of ATP bound Plasmodium falciparum IMP-nucleotidase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, IMP-specific 5'-nucleotidase, ... | 著者 | Carrique, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2019-05-06 | 公開日 | 2020-07-15 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nat Commun, 11, 2020
|
|
6RME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rme by Molmil](/molmil-images/mine/6rme) | Structure of IMP bound Plasmodium falciparum IMP-nucleotidase mutant D172N | 分子名称: | GLYCEROL, IMP-specific 5'-nucleotidase, putative, ... | 著者 | Carrique, L, Ballut, L, Violot, S, Aghajari, N. | 登録日 | 2019-05-06 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase. Nat Commun, 11, 2020
|
|
1EGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1egx by Molmil](/molmil-images/mine/1egx) | SOLUTION STRUCTURE OF THE ENA-VASP HOMOLOGY 1 (EVH1) DOMAIN OF HUMAN VASODILATOR-STIMULATED PHOSPHOPROTEIN (VASP) | 分子名称: | VASODILATOR-STIMULATED PHOSPHOPROTEIN | 著者 | Ball, L, Kuhne, R, Hoffmann, B, Hafner, A, Schmieder, P, Volkmer-Engert, R, Hof, M, Wahl, M, Schneider-Mergener, J, Walter, U, Oschkinat, H, Jarchau, T. | 登録日 | 2000-02-17 | 公開日 | 2000-09-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity. EMBO J., 19, 2000
|
|
2ES0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2es0 by Molmil](/molmil-images/mine/2es0) | Structure of the regulator of G-protein signaling domain of RGS6 | 分子名称: | regulator of G-protein signalling 6 | 著者 | Schoch, G.A, Phillips, C, Turnbull, A, Niesen, F, Johansson, C, Elkins, J.M, Longman, E, Gilealdi, C, Sobott, F, Ball, L, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-10-25 | 公開日 | 2005-11-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
1ZV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zv4 by Molmil](/molmil-images/mine/1zv4) | Structure of the Regulator of G-Protein Signaling 17 (RGSZ2) | 分子名称: | Regulator of G-protein signaling 17 | 著者 | Schoch, G.A, Jansson, A, Elkins, J.M, Haroniti, A, Niesen, F.H, Bunkoczi, G, Lee, W.H, Turnbull, A.P, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Marsden, B, Gileadi, O, Ball, L, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-06-01 | 公開日 | 2005-06-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
1Z57
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z57 by Molmil](/molmil-images/mine/1z57) | Crystal structure of human CLK1 in complex with 10Z-Hymenialdisine | 分子名称: | DEBROMOHYMENIALDISINE, Dual specificity protein kinase CLK1 | 著者 | Debreczeni, J, Das, S, Knapp, S, Bullock, A, Guo, K, Amos, A, Fedorov, O, Edwards, A, Sundstrom, M, von Delft, F, Niesen, F.H, Ball, L, Sobott, F, Arrowsmith, C, Structural Genomics Consortium (SGC) | 登録日 | 2005-03-17 | 公開日 | 2005-04-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation. Structure, 17, 2009
|
|
2AHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ahs by Molmil](/molmil-images/mine/2ahs) | Crystal Structure of the Catalytic Domain of Human Tyrosine Receptor Phosphatase Beta | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta, ... | 著者 | Ugochukwu, E, Eswaran, J, Barr, A, Gileadi, O, Sobott, F, Burgess, N, Ball, L, Bray, J, von Delft, F, Debreczeni, J, Bunkoczi, G, Turnbull, A, Das, S, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-07-28 | 公開日 | 2005-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136, 2009
|
|
5K4Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4z by Molmil](/molmil-images/mine/5k4z) | M. thermoresistible IMPDH in complex with IMP and Compound 6 | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(4-fluorophenyl)-4-(2~{H}-indazol-6-ylsulfamoyl)-3,5-dimethyl-1~{H}-pyrrole-2-carboxamide | 著者 | Pacitto, A, Ascher, D.B, Blundell, T.L. | 登録日 | 2016-05-22 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
|
|
5K4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4x by Molmil](/molmil-images/mine/5k4x) | M. thermoresistible IMPDH in complex with IMP and Compound 1 | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide | 著者 | Pacitto, A, Ascher, D.B, Blundell, T.L. | 登録日 | 2016-05-22 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
|
|
5DU8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5du8 by Molmil](/molmil-images/mine/5du8) | Crystal structure of M. tuberculosis EchA6 bound to GSK572A | 分子名称: | (5R,7S)-5-(4-ethylphenyl)-N-[(5-fluoropyridin-2-yl)methyl]-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, Probable enoyl-CoA hydratase echA6 | 著者 | Cox, J.A.G, Besra, G.S, Futterer, K. | 登録日 | 2015-09-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol, 1, 2016
|
|
5DTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dtp by Molmil](/molmil-images/mine/5dtp) | |
5DU4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5du4 by Molmil](/molmil-images/mine/5du4) | Crystal structure of M. tuberculosis EchA6 bound to ligand GSK366A | 分子名称: | (5R,7S)-5-(4-ethylphenyl)-N-(4-methoxybenzyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, Probable enoyl-CoA hydratase echA6 | 著者 | Cox, J.A.G, Besra, G.S, Futterer, K. | 登録日 | 2015-09-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol, 1, 2016
|
|
5JFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jfo by Molmil](/molmil-images/mine/5jfo) | |
5DU6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5du6 by Molmil](/molmil-images/mine/5du6) | Crystal structure of M. tuberculosis EchA6 bound to ligand GSK059A. | 分子名称: | (5R,7R)-5-(4-ethylphenyl)-N-(4-fluorobenzyl)-7-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, Probable enoyl-CoA hydratase echA6 | 著者 | Cox, J.A.G, Besra, G.S, Futterer, K. | 登録日 | 2015-09-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol, 1, 2016
|
|
5MVR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mvr by Molmil](/molmil-images/mine/5mvr) | |