2AHS

Crystal Structure of the Catalytic Domain of Human Tyrosine Receptor Phosphatase Beta

Summary for 2AHS

• Entry DOI: 10.2210/pdb2ahs/pdb
• Related: 1RPM
• Descriptor: Receptor-type tyrosine-protein phosphatase beta, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: tyrosine receptor phosphatase, beta, human, structural genomics, structural genomics consortium, sgc, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein (Potential): P23467
• Total number of polymer chains: 2
• Total formula weight: 68951.55

Authors

Ugochukwu, E.,Eswaran, J.,Barr, A.,Gileadi, O.,Sobott, F.,Burgess, N.,Ball, L.,Bray, J.,von Delft, F.,Debreczeni, J.,Bunkoczi, G.,Turnbull, A.,Das, S.,Weigelt, J.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-28, release date: 2005-08-09, Last modification date: 2023-08-23)

• Primary citation: Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S.; Large-scale structural analysis of the classical human protein tyrosine phosphatome.; Cell(Cambridge,Mass.), 136:352-363, 2009; PubMed: 19167335; DOI: 10.1016/j.cell.2008.11.038

Experimental method

X-RAY DIFFRACTION (2.1 Å)