1CQP
 
 | | CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION | | 分子名称: | ANTIGEN CD11A (P180), LOVASTATIN, MAGNESIUM ION | | 著者 | Kallen, J, Welzenbach, K, Ramage, P, Geyl, D, Kriwacki, R, Legge, G, Cottens, S, Weitz-Schmidt, G, Hommel, U. | | 登録日 | 1999-08-10 | | 公開日 | 2000-08-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
J.Mol.Biol., 292, 1999
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1BWU
 | | MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM GARLIC (ALLIUM SATIVUM) BULBS COMPLEXED WITH ALPHA-D-MANNOSE | | 分子名称: | PROTEIN (AGGLUTININ), alpha-D-mannopyranose | | 著者 | Chandra, N.R, Ramachandraiah, G, Bachhawat, K, Dam, T.K, Surolia, A, Vijayan, M. | | 登録日 | 1998-09-28 | | 公開日 | 1999-01-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a dimeric mannose-specific agglutinin from garlic: quaternary association and carbohydrate specificity.
J.Mol.Biol., 285, 1999
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1XDG
 | | X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution | | 分子名称: | (1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBENZYL)-4-[2-(METHYLAMINO)-2-OXOETHYL]-2-OXO-1,3-OXAZINAN-6-YL}ETHYL)-3 ,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL (2R)-2-METHYLBUTANOATE, Integrin alpha-L, MAGNESIUM ION | | 著者 | Weitz-Schmidt, G, Welzenbach, K, Dawson, J, Kallen, J. | | 登録日 | 2004-09-06 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo
J.Biol.Chem., 279, 2004
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1XDD
 | | X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution | | 分子名称: | 8-[2-((2S)-4-HYDROXY-1-{[5-(HYDROXYMETHYL)-6-METHOXY-2-NAPHTHYL]METHYL}-6-OXOPIPERIDIN-2-YL)ETHYL]-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL 2-METHYLBUTANOATE, Integrin alpha-L, MAGNESIUM ION | | 著者 | Weitz-Schmidt, G, Welzenbach, K, Dawson, J, Kallen, J. | | 登録日 | 2004-09-06 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo
J.Biol.Chem., 279, 2004
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1XUO
 | | X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution | | 分子名称: | (2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHYL)-1,4-DIAZEPAN-1-YL]-N-METHYL-3-(2-NAPHTHYL)PROPANAMIDE, Integrin alpha-L, MAGNESIUM ION | | 著者 | Wattanasin, S, Kallen, J, Myers, S, Guo, Q, Sabio, M, Ehrhardt, C, Albert, R, Hommel, U, Weckbecker, G, Welzenbach, K. | | 登録日 | 2004-10-26 | | 公開日 | 2005-10-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | 1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1
Bioorg.Med.Chem.Lett., 15, 2005
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2W2H
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4NST
 | | Crystal structure of human Cdk12/Cyclin K in complex with ADP-aluminum fluoride | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | | 著者 | Boesken, C.A, Farnung, L, Anand, K, Geyer, M. | | 登録日 | 2013-11-29 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure and substrate specificity of human Cdk12/Cyclin K.
Nat Commun, 5, 2014
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5HB2
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5CWS
 | | Crystal structure of the intact Chaetomium thermophilum Nsp1-Nup49-Nup57 channel nucleoporin heterotrimer bound to its Nic96 nuclear pore complex attachment site | | 分子名称: | Nucleoporin NIC96, Nucleoporin NSP1, Nucleoporin NUP49, ... | | 著者 | Bley, C.J, Petrovic, S, Paduch, M, Lu, V, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-07-28 | | 公開日 | 2015-10-14 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.77 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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5CWT
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3OKP
 | | Crystal structure of Corynebacterium glutamicum PimB' bound to GDP-Man (orthorhombic crystal form) | | 分子名称: | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE | | 著者 | Batt, S.M, Jabeen, T, Besra, G.S, Futterer, K. | | 登録日 | 2010-08-25 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem., 285, 2010
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3OKA
 | | Crystal structure of Corynebacterium glutamicum PimB' in complex with GDP-Man (triclinic crystal form) | | 分子名称: | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ... | | 著者 | Batt, S.M, Jabeen, T, Besra, G.S, Futterer, K. | | 登録日 | 2010-08-24 | | 公開日 | 2010-09-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem., 285, 2010
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3OKC
 | | Crystal structure of Corynebacterium glutamicum PimB' bound to GDP (orthorhombic crystal form) | | 分子名称: | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Batt, S.M, Jabeen, T, Besra, G.S, Futterer, K. | | 登録日 | 2010-08-24 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem., 285, 2010
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4JO9
 | | Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex 1:2 stoichiometry | | 分子名称: | Nucleoporin p54, Nucleoporin p58/p45 | | 著者 | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | | 登録日 | 2013-03-18 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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4JQ5
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4JO7
 | | Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry | | 分子名称: | Nucleoporin p54, Nucleoporin p58/p45 | | 著者 | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | | 登録日 | 2013-03-17 | | 公開日 | 2014-09-17 | | 最終更新日 | 2016-02-03 | | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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4JNV
 | | Crystal structure of the human Nup57CCS3* coiled-coil segment, space group C2 | | 分子名称: | Nucleoporin p54 | | 著者 | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | | 登録日 | 2013-03-15 | | 公開日 | 2014-09-17 | | 最終更新日 | 2016-02-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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4JNU
 | | Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21 | | 分子名称: | Nucleoporin p54 | | 著者 | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | | 登録日 | 2013-03-15 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.445 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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5HAZ
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5HB8
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5HB5
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5HB4
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5HAY
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5HAX
 | | Crystal structure of Chaetomium thermophilum Nup170 NTD-Nup53 complex | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Nucleoporin NUP170, ... | | 著者 | Lin, D.H, Mobbs, G, Hoelz, A. | | 登録日 | 2015-12-31 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
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5HB6
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