1YH2
 
 | | Ubiquitin-Conjugating Enzyme HSPC150 | | 分子名称: | HSPC150 protein similar to ubiquitin-conjugating enzyme | | 著者 | Walker, J.R, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-01-06 | | 公開日 | 2005-02-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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1YLA
 | | Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2) | | 分子名称: | Ubiquitin-conjugating enzyme E2-25 kDa | | 著者 | Choe, J, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
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1YRV
 | | Novel Ubiquitin-Conjugating Enzyme | | 分子名称: | ubiquitin-conjugating ligase MGC351130 | | 著者 | Walker, J.R, Choe, J, Avvakumov, G.V, Newman, E.M, MacKenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-02-04 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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3CEG
 | | Crystal structure of the UBC domain of baculoviral IAP repeat-containing protein 6 | | 分子名称: | Baculoviral IAP repeat-containing protein 6 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-02-29 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.008 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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3DL2
 | | Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A | | 分子名称: | PHOSPHATE ION, SODIUM ION, Ubiquitin-conjugating enzyme E2 variant 3 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Bountra, C, Wolkstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-06-26 | | 公開日 | 2008-07-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Investigation Into the L-Lactate Dehydrogenase Domain of Human Ubiquitin-Conjugating Enzyme E2-Like Isoform A.
To be Published
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3DB4
 | | Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, SULFATE ION | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-05-30 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
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3BZH
 | | Crystal structure of human ubiquitin-conjugating enzyme E2 E1 | | 分子名称: | GLYCEROL, Ubiquitin-conjugating enzyme E2 E1 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-01-18 | | 公開日 | 2008-02-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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2F4W
 | | Human ubiquitin-conjugating enzyme E2 J2 | | 分子名称: | ubiquitin-conjugating enzyme E2, J2 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Finerty Jr, P.J, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-11-24 | | 公開日 | 2005-12-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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3DB3
 | | Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-05-30 | | 公開日 | 2008-09-16 | | 最終更新日 | 2012-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
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3EPZ
 | | Structure of the replication foci-targeting sequence of human DNA cytosine methyltransferase DNMT1 | | 分子名称: | DNA (cytosine-5)-methyltransferase 1, GLYCEROL, SODIUM ION, ... | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-30 | | 公開日 | 2008-11-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.
J.Biol.Chem., 286, 2011
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1ZKH
 | | Solution structure of a human ubiquitin-like domain in SF3A1 | | 分子名称: | Splicing factor 3 subunit 1 | | 著者 | Lukin, J.A, Dhe-Paganon, S, Guido, V, Lemak, A, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Edwards, A, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2005-05-02 | | 公開日 | 2005-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a human ubiquitin-like domain in SF3A1
To be Published
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1Z6U
 | | Np95-like ring finger protein isoform b [Homo sapiens] | | 分子名称: | Np95-like ring finger protein isoform b, ZINC ION | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-03-23 | | 公開日 | 2005-05-03 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 2.1 Angstrom Crystal Structure of the Human Ubiquitin Liagse NIRF
To be Published
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1ZDN
 | | Ubiquitin-conjugating enzyme E2S | | 分子名称: | SODIUM ION, Ubiquitin-conjugating enzyme E2S | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-04-14 | | 公開日 | 2005-05-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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2A7L
 | | Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284 | | 分子名称: | Hypothetical ubiquitin-conjugating enzyme LOC55284, SODIUM ION | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-07-05 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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2A4D
 | | Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) | | 分子名称: | Ubiquitin-conjugating enzyme E2 variant 1 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-06-28 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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1YQB
 | | Human Ubiquilin 3 | | 分子名称: | Ubiquilin 3 | | 著者 | Walker, J.R, Xue, S, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-02-01 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Ubiquitin-like domain of Human Ubiquilin 3
To be Published
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1ZUO
 | | Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation | | 分子名称: | BETA-MERCAPTOETHANOL, Hypothetical protein LOC92912 | | 著者 | Walker, J.R, Avvakumov, G.V, Cui, H, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-05-31 | | 公開日 | 2005-07-05 | | 最終更新日 | 2012-11-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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2AWF
 | | Structure of human Ubiquitin-conjugating enzyme E2 G1 | | 分子名称: | Ubiquitin-conjugating enzyme E2 G1 | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty, P, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-09-01 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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2IIP
 | | Human Nicotinamide N-methyltransferase | | 分子名称: | Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Bernstein, G, Min, J, Wu, H, Tempel, W, Zeng, H, Loppnau, P, Avvakumov, G.V, Wasney, G, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2006-09-28 | | 公開日 | 2006-10-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The Crystal Structure of Human Nicotinamide N-methyltransferase in complex with SAH
To be Published
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2NQ3
 | | Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase | | 分子名称: | CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-10-30 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
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2OB4
 | | Human Ubiquitin-Conjugating Enzyme CDC34 | | 分子名称: | Ubiquitin-conjugating enzyme E2-32 kDa complementing | | 著者 | Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-12-18 | | 公開日 | 2006-12-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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2NSQ
 | | Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-06 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
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2O25
 | | Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9 | | 分子名称: | SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-29 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa
To be Published
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1F5F
 | | CRYSTAL STRUCTURE OF THE N-TERMINAL G-DOMAIN OF SHBG IN COMPLEX WITH ZINC | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, ISOPROPYL ALCOHOL, ... | | 著者 | Avvakumov, V.A, Muller, Y.A, Hammond, G.L. | | 登録日 | 2000-06-14 | | 公開日 | 2000-09-06 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site.
J.Biol.Chem., 275, 2000
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3MTN
 | | Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor | | 分子名称: | CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ... | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-04-30 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
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