2A4D
Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1)
Summary for 2A4D
Entry DOI | 10.2210/pdb2a4d/pdb |
Descriptor | Ubiquitin-conjugating enzyme E2 variant 1 (2 entities in total) |
Functional Keywords | alternative splicing; nuclear protein; ubl conjugation pathway, ubiquitin, ubiquitin- conjugating enzyme, ligase, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q13404 |
Total number of polymer chains | 1 |
Total formula weight | 18027.58 |
Authors | Walker, J.R.,Avvakumov, G.V.,Xue, S.,Newman, E.M.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-06-28, release date: 2005-07-12, Last modification date: 2023-08-23) |
Primary citation | Sheng, Y.,Hong, J.H.,Doherty, R.,Srikumar, T.,Shloush, J.,Avvakumov, G.V.,Walker, J.R.,Xue, S.,Neculai, D.,Wan, J.W.,Kim, S.K.,Arrowsmith, C.H.,Raught, B.,Dhe-Paganon, S. A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11:329-341, 2012 Cited by PubMed: 22496338DOI: 10.1074/mcp.O111.013706 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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