4GS4
 
 | | Structure of the alpha-tubulin acetyltransferase, alpha-TAT1 | | 分子名称: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase | | 著者 | Friedmann, D.R, Fan, J, Marmorstein, R. | | 登録日 | 2012-08-27 | | 公開日 | 2012-10-17 | | 最終更新日 | 2013-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | | 主引用文献 | Structure of the alpha-tubulin acetyltransferase, alpha TAT1, and implications for tubulin-specific acetylation.
Proc.Natl.Acad.Sci.USA, 109, 2012
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8ETB
 | | the crystal structure of a rationally designed zinc sensor based on maltose binding protein - Zn binding conformation | | 分子名称: | ACETATE ION, ZINC ION, Zinc Sensor protein | | 著者 | Zhao, Z, Zhou, M, Zemerov, S.D, Marmorstein, R, Dmochowski, I.J. | | 登録日 | 2022-10-16 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Rational design of a genetically encoded NMR zinc sensor.
Chem Sci, 14, 2023
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8F23
 | | The crystal structure of a rationally designed zinc sensor based on maltose binding protein - Apo conformation | | 分子名称: | Zinc Sensor protein | | 著者 | Zhao, Z, Zhou, M, Zemerov, S.d, Marmorstein, R, Dmochowski, I.J. | | 登録日 | 2022-11-06 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Rational design of a genetically encoded NMR zinc sensor.
Chem Sci, 14, 2023
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7LJ9
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4RLP
 | | Human p70s6k1 with ruthenium-based inhibitor FL772 | | 分子名称: | CHLORIDE ION, [(amino-kappaN)methanethiolato](3-fluoro-9-methoxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(N-methyl-1,4,7-trithiecan-9-amine-kappa~3~S~1~,S~4~,S~7~)ruthenium, p70S6K1 | | 著者 | Domsic, J.F, Barber-Rotenberg, J, Salami, J, Qin, J, Marmorstein, R. | | 登録日 | 2014-10-17 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
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4RLO
 | | Human p70s6k1 with ruthenium-based inhibitor EM5 | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Domsic, J.F, Barber-Rotenberg, J, Salami, J, Qin, J, Marmorstein, R. | | 登録日 | 2014-10-17 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.527 Å) | | 主引用文献 | Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
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3LBX
 | | Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex | | 分子名称: | Spectrin alpha chain, erythrocyte, Spectrin beta chain | | 著者 | Ipsaro, J.J, Harper, S.L, Messick, T.E, Marmorstein, R, Mondragon, A, Speicher, D.W. | | 登録日 | 2010-01-08 | | 公開日 | 2010-03-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.
Blood, 115, 2010
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6POE
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5WJD
 | | Crystal structure of Naa80 bound to acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, CG8481, isoform B, ... | | 著者 | Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T. | | 登録日 | 2017-07-21 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5WJE
 | | Crystal structure of Naa80 bound to a bisubstrate analogue | | 分子名称: | Actin N-terminus peptide, CARBOXYMETHYL COENZYME *A, CG8481, ... | | 著者 | Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T. | | 登録日 | 2017-07-21 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.765 Å) | | 主引用文献 | Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1TRO
 | | CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION | | 分子名称: | DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN | | 著者 | Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B. | | 登録日 | 1992-08-30 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
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7LLA
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5ICV
 | | Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue | | 分子名称: | MET-LYS-ALA-VAL-LIG, N-alpha-acetyltransferase 60, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate | | 著者 | Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T. | | 登録日 | 2016-02-23 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.
Structure, 24, 2016
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5ICW
 | | Crystal structure of human NatF (hNaa60) homodimer bound to Coenzyme A | | 分子名称: | CHLORIDE ION, COENZYME A, N-alpha-acetyltransferase 60 | | 著者 | Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T. | | 登録日 | 2016-02-23 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.
Structure, 24, 2016
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7LIW
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8G1E
 | | Structure of ACLY-D1026A-products-asym | | 分子名称: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wei, X, Marmorstein, R. | | 登録日 | 2023-02-02 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
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8G0L
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8G5D
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8G1F
 | | Structure of ACLY-D1026A-products | | 分子名称: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wei, X, Marmorstein, R. | | 登録日 | 2023-02-02 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
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1YGH
 | | HAT DOMAIN OF GCN5 FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | GLYCEROL, PROTEIN (TRANSCRIPTIONAL ACTIVATOR GCN5) | | 著者 | Trievel, R.C, Rojas, J.R, Sterner, D.E, Venkataramani, R, Wang, L, Zhou, J, Allis, C.D, Berger, S.L, Marmorstein, R. | | 登録日 | 1999-05-27 | | 公開日 | 1999-08-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1ZX2
 | | Crystal Structure of Yeast UBP3-associated Protein BRE5 | | 分子名称: | UBP3-associated protein BRE5 | | 著者 | Li, K, Zhao, K, Ossareh-Nazari, B, Da, G, Dargemont, C, Marmorstein, R. | | 登録日 | 2005-06-06 | | 公開日 | 2005-06-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for interaction between the Ubp3 deubiquitinating enzyme and its Bre5 cofactor
J.Biol.Chem., 280, 2005
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6UIA
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1FY7
 | | CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A | | 分子名称: | COENZYME A, ESA1 HISTONE ACETYLTRANSFERASE, SODIUM ION | | 著者 | Yan, Y, Barlev, N.A, Haley, R.H, Berger, S.L, Marmorstein, R. | | 登録日 | 2000-09-28 | | 公開日 | 2000-11-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases.
Mol.Cell, 6, 2000
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5DFP
 | | Crystal structure of PAK1 in complex with an inhibitor compound FRAX1036 | | 分子名称: | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, DIMETHYL SULFOXIDE, Serine/threonine-protein kinase PAK 1 | | 著者 | Maksimoska, J, Marmorstein, R, Wang, W. | | 登録日 | 2015-08-27 | | 公開日 | 2016-01-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.
Acs Med.Chem.Lett., 6, 2015
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7RB3
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