7TUH
| Crystal structure of anti-tapasin PaSta2-Fab | 分子名称: | PaSta2 Fab heavy chain, PaSta2 Fab kappa light chain | 著者 | Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H. | 登録日 | 2022-02-02 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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8TQA
| Crystal structure of Fab.28.14.8 in complex with MHC-I (H2-Db) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | 登録日 | 2023-08-06 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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8TQ8
| Crystal structure of Fab.34.5.8 in complex with MHC-I (H2-Dd) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Fab.34.5.8 Heavy chain, ... | 著者 | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | 登録日 | 2023-08-06 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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8TQ9
| Crystal structure of Fab.S19.8 in complex with MHC-I (H2-Dd) | 分子名称: | Beta-2-microglobulin, Fab.S19.8 Heavy Chain, Fab.S19.8 Light Chain, ... | 著者 | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | 登録日 | 2023-08-06 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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8TQ7
| Crystal structure of Fab.34.2.12 in complex with MHC-I (H2-Dd) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Fab 34.2.12 Light Chain, ... | 著者 | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | 登録日 | 2023-08-06 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212, 2024
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7MFU
| Crystal structure of synthetic nanobody (Sb14+Sb68) complexes with SARS-CoV-2 receptor binding domain | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Spike protein S1, ... | 著者 | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2021-04-11 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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5WES
| Crystal Structure H2-Dd with disulfide-linked 5mer peptide | 分子名称: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2017-07-10 | 公開日 | 2017-10-18 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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5WEU
| Crystal Structure of H2-Dd with disulfide-linked 10mer peptide | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, Envelope glycoprotein gp160, ... | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2017-07-10 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.584 Å) | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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5WET
| Crystal Structure of H2-Dd with disulfide-linked 6mer peptide | 分子名称: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2017-07-10 | 公開日 | 2017-10-18 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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5WER
| Crystal Structure of TAPBPR and H2-Dd complex | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ... | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2017-07-10 | 公開日 | 2017-10-18 | 最終更新日 | 2019-08-28 | 実験手法 | X-RAY DIFFRACTION (3.412 Å) | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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5KD7
| Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PV9) of HIV gp120 MN Isolate (IGPGRAFYV) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Jiang, J, Natarajan, K, Margulies, D. | 登録日 | 2016-06-07 | 公開日 | 2017-10-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity. J. Immunol., 200, 2018
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5KD4
| Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PVI10) of HIV gp120 MN Isolate (IGPGRAFYVI) | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... | 著者 | Jiang, J, Natarajan, K, Margulies, D. | 登録日 | 2016-06-07 | 公開日 | 2017-10-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity. J. Immunol., 200, 2018
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1QO3
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1JA3
| Crystal Structure of the Murine NK Cell Inhibitory Receptor Ly-49I | 分子名称: | MHC class I recognition receptor Ly49I | 著者 | Dimasi, N, Sawicki, W.M, Reineck, L.A, Li, Y, Natarajan, K, Murgulies, D.H, Mariuzza, A.R. | 登録日 | 2001-05-29 | 公開日 | 2002-07-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family. J.Mol.Biol., 320, 2002
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5IVX
| Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Natarajan, K, Jiang, J, Margulies, D. | 登録日 | 2016-03-21 | 公開日 | 2017-03-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An allosteric site in the T-cell receptor C beta domain plays a critical signalling role. Nat Commun, 8, 2017
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5IW1
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6B9K
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7N0H
| CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Jiang, J, Huang, R, Margulies, D. | 登録日 | 2021-05-25 | 公開日 | 2021-06-02 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7N0G
| CryoEm structure of SARS-CoV-2 spike protein (S-6P, 1-up) in complex with sybodies (Sb45) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Jiang, J, Huang, R, Margulies, D. | 登録日 | 2021-05-25 | 公開日 | 2021-06-02 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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5T7G
| Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PT9) of HIV gp120 MN Isolate (IGPGRAFYT) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Jiang, J, Natarajan, K, Margulies, D. | 登録日 | 2016-09-04 | 公開日 | 2017-10-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | 主引用文献 | Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity. J. Immunol., 200, 2018
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5TS1
| Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YYQSGLSIV) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Jiang, J, Natarajan, K, Margulies, D. | 登録日 | 2016-10-27 | 公開日 | 2018-05-09 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice. Eur.J.Immunol., 2019
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5TRZ
| Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YQSGLSIVM) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Jiang, J, Natarajan, K, Margulies, D. | 登録日 | 2016-10-27 | 公開日 | 2018-05-09 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.247 Å) | 主引用文献 | MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice. Eur.J.Immunol., 2019
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7U9O
| SARS-CoV-2 spike trimer RBD in complex with Fab NE12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ... | 著者 | Tsybovsky, Y, Kwong, P.D, Farci, P. | 登録日 | 2022-03-11 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants. Cell Rep, 41, 2022
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7U9P
| SARS-CoV-2 spike trimer RBD in complex with Fab NA8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ... | 著者 | Tsybovsky, Y, Kwong, P.D, Farci, P. | 登録日 | 2022-03-11 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants. Cell Rep, 41, 2022
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1P4L
| Crystal structure of NK receptor Ly49C mutant with its MHC class I ligand H-2Kb | 分子名称: | Beta-2-microglobulin, LY49-C, MHC CLASS I H-2KB HEAVY CHAIN, ... | 著者 | Dam, J, Guan, R, Natarajan, K, Dimasi, N, Mariuzza, R.A. | 登録日 | 2003-04-23 | 公開日 | 2003-11-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nat.Immunol., 4, 2003
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