6W1S
 
 | | Atomic model of the mammalian Mediator complex | | 分子名称: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | | 著者 | Zhao, H, Young, N, Asturias, F. | | 登録日 | 2020-03-04 | | 公開日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
Cell, 178, 2019
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7MY2
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7MY3
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8GJV
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8GW7
 | | AtSLAC1 6D mutant in open state | | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | | 著者 | Lee, Y, Lee, S. | | 登録日 | 2022-09-16 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
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8GW6
 | | AtSLAC1 6D mutant in closed state | | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | | 著者 | Lee, Y, Lee, S. | | 登録日 | 2022-09-16 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
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8J0J
 | | AtSLAC1 8D mutant in closed state | | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein | | 著者 | Lee, Y, Lee, S. | | 登録日 | 2023-04-11 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
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8J1E
 | | AtSLAC1 in open state | | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein | | 著者 | Lee, Y, Lee, S. | | 登録日 | 2023-04-12 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
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7S24
 | | Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL | | 著者 | Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R. | | 登録日 | 2021-09-03 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing.
Nat Commun, 13, 2022
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4E90
 | | Human phosphodiesterase 9 in complex with inhibitors | | 分子名称: | 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | | 著者 | Liu, S. | | 登録日 | 2012-03-20 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors.
J.Med.Chem., 55, 2012
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1PAX
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4G2L
 | | Human PDE9 in complex with selective compound | | 分子名称: | 1-cyclopentyl-6-{(1R)-1-[3-(pyrimidin-2-yl)azetidin-1-yl]ethyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | | 著者 | Liu, S. | | 登録日 | 2012-07-12 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors.
J.Med.Chem., 55, 2012
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4G2J
 | | Human pde9 in complex with selective compound | | 分子名称: | 1-cyclopentyl-6-[(1R)-1-(3-phenoxyazetidin-1-yl)ethyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | | 著者 | Liu, S. | | 登録日 | 2012-07-12 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors.
J.Med.Chem., 55, 2012
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7ZO8
 | | cryo-EM structure of CGT ABC transporter in nanodisc apo state | | 分子名称: | Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, DIUNDECYL PHOSPHATIDYL CHOLINE | | 著者 | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | | 登録日 | 2022-04-24 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella.
Nat.Struct.Mol.Biol., 29, 2022
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7ZOA
 | | cryo-EM structure of CGT ABC transporter in presence of CBG substrate | | 分子名称: | Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, Cyclooctadecakis-(1-2)-(beta-D-glucopyranose) | | 著者 | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | | 登録日 | 2022-04-24 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella.
Nat.Struct.Mol.Biol., 29, 2022
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7ZO9
 | | cryo-EM structure of CGT ABC transporter in vanadate trapped state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, VANADATE ION | | 著者 | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | | 登録日 | 2022-04-24 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella.
Nat.Struct.Mol.Biol., 29, 2022
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7ZNU
 | | cryo-EM structure of CGT ABC transporter in detergent micelle | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta-(1-->2)glucan export ATP-binding/permease protein NdvA, VANADATE ION | | 著者 | Jaroslaw, S, Dong, C.N, Frank, L, Na, W, Renato, Z, Seunho, J, Henning, S, Christoph, D. | | 登録日 | 2022-04-22 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella.
Nat.Struct.Mol.Biol., 29, 2022
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3PAX
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4IMK
 | | Uncrossed Fab binding to human Angiopoietin 2 | | 分子名称: | GLYCEROL, Heavy Chain, Light Chain, ... | | 著者 | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | | 登録日 | 2013-01-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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4IML
 | | CrossFab binding to human Angiopoietin 2 | | 分子名称: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | | 著者 | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | | 登録日 | 2013-01-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.931 Å) | | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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2PAX
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2PAW
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7D9N
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4PAX
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2JSA
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