4R05
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![BU of 4r05 by Molmil](/molmil-images/mine/4r05) | Crystal structure of the refolded DENV3 methyltransferase | 分子名称: | Nonstructural protein NS5 | 著者 | Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M. | 登録日 | 2014-07-29 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase. Protein Sci., 24, 2015
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1IJY
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![BU of 1ijy by Molmil](/molmil-images/mine/1ijy) | CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MOUSE FRIZZLED 8 (MFZ8) | 分子名称: | FRIZZLED HOMOLOG 8 | 著者 | Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J. | 登録日 | 2001-05-01 | 公開日 | 2001-07-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature, 412, 2001
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1IJX
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![BU of 1ijx by Molmil](/molmil-images/mine/1ijx) | CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB) | 分子名称: | SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3, SULFATE ION | 著者 | Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J. | 登録日 | 2001-04-30 | 公開日 | 2001-07-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature, 412, 2001
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7EO8
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![BU of 7eo8 by Molmil](/molmil-images/mine/7eo8) | Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin | 分子名称: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | 著者 | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | 登録日 | 2021-04-21 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2808516 Å) | 主引用文献 | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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5YMR
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![BU of 5ymr by Molmil](/molmil-images/mine/5ymr) | The Crystal Structure of IseG | 分子名称: | 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL | 著者 | Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z. | 登録日 | 2017-10-22 | 公開日 | 2019-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun, 10, 2019
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5FI4
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![BU of 5fi4 by Molmil](/molmil-images/mine/5fi4) | Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model | 分子名称: | GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | 著者 | Elling, R.A, Knapp, M.S, Han, W, Daniel, L.M, Xy, Y, Burger, M.T, Ni, Z, Smith, A, Lan, J, Williams, T, Verhagen, J, Huh, K, Merritt, H, Chan, J, Kaufman, S, Voliva, C.F, Pecchi, S. | 登録日 | 2015-12-22 | 公開日 | 2016-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model. Bioorg.Med.Chem.Lett., 26, 2016
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5YTE
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![BU of 5yte by Molmil](/molmil-images/mine/5yte) | Large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with with natural dT:dATP base pair | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... | 著者 | Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
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5YTD
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![BU of 5ytd by Molmil](/molmil-images/mine/5ytd) | large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the natural base pair 5fC:dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(5FC)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... | 著者 | Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
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5YTC
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![BU of 5ytc by Molmil](/molmil-images/mine/5ytc) | Large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with the unnatural base M-fC pair with dATP in the active site | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*(92F)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC)P*(DOC))-3'), ... | 著者 | Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Yi, C.Q. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
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5YTF
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![BU of 5ytf by Molmil](/molmil-images/mine/5ytf) | Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dA | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... | 著者 | Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
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5C27
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![BU of 5c27 by Molmil](/molmil-images/mine/5c27) | Crystal structure of SYK in complex with compound 2 | 分子名称: | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-N-[4-(methylcarbamoyl)phenyl]benzamide, GLU-VAL-TYR-GLU-SER, GLYCEROL, ... | 著者 | Han, S, Chang, J. | 登録日 | 2015-06-15 | 公開日 | 2015-10-07 | 最終更新日 | 2016-02-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP). Chemmedchem, 11, 2016
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8TP6
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![BU of 8tp6 by Molmil](/molmil-images/mine/8tp6) | H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 4-1-1E02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 4-1-1E02 Fab, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TP7
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![BU of 8tp7 by Molmil](/molmil-images/mine/8tp7) | H2 hemagglutinin (A/Singapore/1/1957) in complex with Sa-targeting Fab 4-1-1G03 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 4-1-1G03, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TP9
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![BU of 8tp9 by Molmil](/molmil-images/mine/8tp9) | H2 hemagglutinin (A/Singapore/1/1957) in complex with medial-junction-targeting Fab 2-2-1G06 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TP3
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![BU of 8tp3 by Molmil](/molmil-images/mine/8tp3) | H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1F05 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TP4
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![BU of 8tp4 by Molmil](/molmil-images/mine/8tp4) | H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 1-1-1E04 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TP5
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![BU of 8tp5 by Molmil](/molmil-images/mine/8tp5) | H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1E04 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TPA
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![BU of 8tpa by Molmil](/molmil-images/mine/8tpa) | H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TP2
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![BU of 8tp2 by Molmil](/molmil-images/mine/8tp2) | H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting 1-1-1F05 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ... | 著者 | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | 登録日 | 2023-08-04 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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7F42
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![BU of 7f42 by Molmil](/molmil-images/mine/7f42) | |
7F41
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![BU of 7f41 by Molmil](/molmil-images/mine/7f41) | |
7F43
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![BU of 7f43 by Molmil](/molmil-images/mine/7f43) | |
6KY5
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![BU of 6ky5 by Molmil](/molmil-images/mine/6ky5) | Crystal structure of a hydrolase mutant | 分子名称: | PET hydrolase, SULFATE ION | 著者 | Cui, Y.L, Chen, Y.C, Liu, X.Y, Dong, S.J, Han, J, Xiang, H, Chen, Q, Liu, H.Y, Han, X, Liu, W.D, Tang, S.Y, Wu, B. | 登録日 | 2019-09-16 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.631 Å) | 主引用文献 | Computational redesign of PETase for plasticbiodegradation by GRAPE strategy. Biorxiv, 2020
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7MU8
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![BU of 7mu8 by Molmil](/molmil-images/mine/7mu8) | Structure of the minimally glycosylated human CEACAM1 N-terminal domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, ... | 著者 | Belcher Dufrisne, M, Swope, N, Kieber, M, Yang, J.Y, Han, J, Li, J, Moremen, K.W, Prestegard, J.H, Columbus, L. | 登録日 | 2021-05-14 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Human CEACAM1 N-domain dimerization is independent from glycan modifications. Structure, 30, 2022
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6JCF
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![BU of 6jcf by Molmil](/molmil-images/mine/6jcf) | Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron | 分子名称: | CACODYLATE ION, Integrase | 著者 | Park, J.H, Han, J, Kim, T.H, Yun, J.H, Lee, W. | 登録日 | 2019-01-28 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | 主引用文献 | Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers. Int J Mol Sci, 20, 2019
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