6J3P
| Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n | 分子名称: | 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A | 著者 | Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y. | 登録日 | 2019-01-05 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J.Med.Chem., 62, 2019
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5WJM
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8YZ7
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5X39
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5X34
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5B6E
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2MXP
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4LGJ
| Crystal structure and mechanism of a type III secretion protease | 分子名称: | Uncharacterized protein, ZINC ION | 著者 | Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W. | 登録日 | 2013-06-28 | 公開日 | 2014-01-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure and mechanism of a type III secretion protease, NleC Acta Crystallogr.,Sect.D, 70, 2014
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4LGI
| N-terminal truncated NleC structure | 分子名称: | Uncharacterized protein | 著者 | Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W. | 登録日 | 2013-06-28 | 公開日 | 2014-01-15 | 最終更新日 | 2015-02-25 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structure and mechanism of a type III secretion protease, NleC Acta Crystallogr.,Sect.D, 70, 2014
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5XMK
| Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1 | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | 登録日 | 2017-05-15 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution Nat Commun, 8, 2017
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5XMI
| Cryo-EM Structure of the ATP-bound VPS4 mutant-E233Q hexamer (masked) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4 | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | 登録日 | 2017-05-15 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution Nat Commun, 8, 2017
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5X38
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5X35
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5X36
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5X37
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5X3C
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5J87
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5B6D
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2M7T
| Solution NMR Structure of Engineered Cystine Knot Protein 2.5D | 分子名称: | Cystine Knot Protein 2.5D | 著者 | Cochran, F.V, Das, R. | 登録日 | 2013-04-30 | 公開日 | 2014-05-07 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10. Proteins, 82 Suppl 2, 2014
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3VB5
| Crystal structure of SARS-CoV 3C-like protease with C4Z | 分子名称: | 1,2-ETHANEDIOL, 3C-like proteinase, C4Z inhibitor | 著者 | Chuck, C.P, Wong, K.B. | 登録日 | 2011-12-31 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases Eur.J.Med.Chem., 59C, 2012
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3VB4
| Crystal structure of SARS-CoV 3C-like protease with B4Z | 分子名称: | 1,2-ETHANEDIOL, 3C-like proteinase, B4Z inhibitor, ... | 著者 | Chuck, C.P, Wong, K.B. | 登録日 | 2011-12-31 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases Eur.J.Med.Chem., 59C, 2012
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5ULU
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5ULY
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5USG
| 5-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | 分子名称: | DNA (5'-D(*AP*(T5S)P*GP*(T5S)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | 著者 | Fang, Z, Qin, L, Huang, Z. | 登録日 | 2017-02-13 | 公開日 | 2017-03-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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5UN2
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