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7OPB
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BU of 7opb by Molmil
IL7R in complex with an antagonist
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ...
著者Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N.
登録日2021-05-31
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
6NY8
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BU of 6ny8 by Molmil
Crystal structure of computationally designed protein XAA_GVDQ with calcium
分子名称: CALCIUM ION, CHLORIDE ION, Design construct XAA_GVDQ
著者Wei, K.Y, Bick, M.J.
登録日2019-02-11
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NYE
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BU of 6nye by Molmil
Crystal structure of computationally designed protein XAX
分子名称: Design construct XAX
著者Wei, K.Y, Bick, M.J.
登録日2019-02-11
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NZ1
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BU of 6nz1 by Molmil
Crystal structure of computationally designed protein XXA_GVDQ
分子名称: Design construct XXA_GVDQ
著者Wei, K.Y, Bick, M.J.
登録日2019-02-12
公開日2020-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NX2
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BU of 6nx2 by Molmil
Crystal structure of computationally designed protein AAA
分子名称: BROMIDE ION, Design construct AAA
著者Wei, K.Y, Bick, M.J.
登録日2019-02-07
公開日2020-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NYI
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BU of 6nyi by Molmil
Crystal structure of computationally designed protein XXA
分子名称: Design construct XXA
著者Wei, K.Y, Bick, M.J.
登録日2019-02-11
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NYK
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BU of 6nyk by Molmil
Crystal structure of computationally designed protein XAX_GGDQ
分子名称: Design construct XAX_GGDQ
著者Wei, K.Y, Bick, M.J.
登録日2019-02-11
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NXM
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BU of 6nxm by Molmil
Crystal structure of computationally designed protein XAA_GVDQ
分子名称: Design construct XAA_GVDQ
著者Wei, K.Y, Bick, M.J.
登録日2019-02-08
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NZ3
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BU of 6nz3 by Molmil
Crystal structure of computationally designed protein XAA_GGHN
分子名称: CHLORIDE ION, Design construct XAA_GGHN
著者Wei, K.Y, Bick, M.J.
登録日2019-02-12
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
5JG9
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BU of 5jg9 by Molmil
Crystal structure of the de novo mini protein gEHEE_06
分子名称: CHLORIDE ION, GLYCEROL, de novo design, ...
著者Rupert, P.B, Johnsen, W.A.
登録日2016-04-19
公開日2016-09-28
最終更新日2016-11-02
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Accurate de novo design of hyperstable constrained peptides.
Nature, 538, 2016
7N1J
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BU of 7n1j by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
分子名称: Binder, Fibroblast growth factor receptor 4
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1K
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BU of 7n1k by Molmil
Crystal structure of a de novo-designed mini-protein targeting FGFR
分子名称: Binder
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N3T
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BU of 7n3t by Molmil
TrkA ECD complex with designed miniprotein ligand
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jude, K.M, Cao, L, Garcia, K.C.
登録日2021-06-01
公開日2022-04-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7LDF
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BU of 7ldf by Molmil
High resolution NMR solution structure of a de novo designed minimal thioredoxin fold protein
分子名称: Minimal thioredoxin fold protein, ems_thioM_802
著者Urbauer, J.L, Strauch, E.M.
登録日2021-01-13
公開日2022-07-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Sampling of structure and sequence space of small protein folds.
Nat Commun, 13, 2022
6Z2I
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BU of 6z2i by Molmil
Crystal structure of DeNovoTIM6, a de novo designed TIM barrel
分子名称: de novo designed TIM barrel DeNovoTIM6
著者Romero-Romero, S, Kordes, S, Shanmugaratnam, S, Rodriguez-Romero, A, Fernandez-Velasco, D.A, Hocker, B.
登録日2020-05-15
公開日2021-07-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
J.Mol.Biol., 433, 2021
6Z1L
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BU of 6z1l by Molmil
A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.12
分子名称: 1,2-ETHANEDIOL, BH32.12 protein, PHOSPHATE ION
著者Levy, C.W.
登録日2020-05-13
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Nat.Chem., 14, 2022
6Z1K
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BU of 6z1k by Molmil
A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.6
分子名称: 1,2-ETHANEDIOL, BH32.6 protein, CALCIUM ION, ...
著者Levy, C.W.
登録日2020-05-13
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Nat.Chem., 14, 2022
8OYS
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BU of 8oys by Molmil
De novo designed TIM barrel fold TBF_24
分子名称: CHLORIDE ION, De novo designed TIM-barrel
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Computational design of soluble and functional membrane protein analogues.
Nature, 631, 2024
8OYV
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BU of 8oyv by Molmil
De novo designed Claudin fold CLF_4
分子名称: De novo designed soluble Claudin
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Computational design of soluble and functional membrane protein analogues.
Nature, 631, 2024
8OYX
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BU of 8oyx by Molmil
De novo designed soluble GPCR-like fold GLF_18
分子名称: De novo designed soluble GPCR-like protein, PHOSPHATE ION
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Computational design of soluble and functional membrane protein analogues.
Nature, 631, 2024
8OYY
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BU of 8oyy by Molmil
De novo designed soluble GPCR-like fold GLF_32
分子名称: CHLORIDE ION, De novo designed soluble GPCR-like protein, POTASSIUM ION
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Computational design of soluble and functional membrane protein analogues.
Nature, 631, 2024
8OYW
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BU of 8oyw by Molmil
De novo designed rhomboid protease-like fold RPF_9
分子名称: De novo designed soluble Rhomboid protease-like protein, SODIUM ION
著者Pacesa, M, Correia, B.E.
登録日2023-05-05
公開日2023-10-18
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Computational design of soluble and functional membrane protein analogues.
Nature, 631, 2024
6EGC
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BU of 6egc by Molmil
Single-chain version of 2L4HC2_23 (PDB 5J0K)
分子名称: SC_2L4HC2_23
著者Bick, M.J, Chen, Z, DiMaio, F.
登録日2018-08-19
公開日2019-05-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Self-Assembling 2D Arrays with de Novo Protein Building Blocks.
J.Am.Chem.Soc., 141, 2019
7QFJ
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BU of 7qfj by Molmil
Crystal structure of S-layer protein SlpX from Lactobacillus acidophilus, domain II (aa 194-362)
分子名称: SlpX
著者Sagmeister, T, Pavkov-Keller, T, Buhlheller, C, Baek, M, Read, R, Baker, D.
登録日2021-12-06
公開日2022-12-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The molecular architecture of Lactobacillus S-layer: Assembly and attachment to teichoic acids.
Proc.Natl.Acad.Sci.USA, 121, 2024
8V3B
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BU of 8v3b by Molmil
Computational Designed Nanocage O43_129_+4
分子名称: O43_129_+4 component A, O43_129_+4 component B
著者Carr, K.D, Weidle, C, Borst, A.J.
登録日2023-11-27
公開日2024-03-13
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Blueprinting extendable nanomaterials with standardized protein blocks.
Nature, 627, 2024

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