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8IZU
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BU of 8izu by Molmil
Crystal structure of the N-terminal domain (residues 1-137) of MPXV A7
分子名称: GLYCEROL, NICKEL (II) ION, Virion morphogenesis protein OPG132
著者Ni, X.C, Lei, J.
登録日2023-04-08
公開日2024-04-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural analysis of conformational changes in the mpox virus A7 protein.
Virol Sin, 39, 2024
8J4F
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BU of 8j4f by Molmil
Structure of human Nav1.7 in complex with Hardwickii acid
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (4~{a}~{R},5~{S},6~{R},8~{a}~{R})-5-[2-(furan-3-yl)ethyl]-5,6,8~{a}-trimethyl-3,4,4~{a},6,7,8-hexahydronaphthalene-1-carboxylic acid, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
著者Wu, Q.R, Yan, N.
登録日2023-04-19
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mapping of Na v 1.7 antagonists.
Nat Commun, 14, 2023
7F7E
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BU of 7f7e by Molmil
SARS-CoV-2 S protein RBD in complex with A5-10 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A5-10 Fab, Light chain of A5-10 Fab, ...
著者Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B.
登録日2021-06-29
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants.
Emerg Microbes Infect, 11, 2022
7DLH
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BU of 7dlh by Molmil
Crystallization of Cationic Peroxidase from Proso Millet and Identification of Its Phosphatase Active Sites
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Cui, x.d, Wang, t.f, Wang, k.
登録日2020-11-27
公開日2021-12-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.789 Å)
主引用文献Crystallization of Cationic Peroxidase from Proso Millet and Identification of Its Phosphatase Active Sites
To Be Published
5YE9
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BU of 5ye9 by Molmil
The crystal structure of Lp-PLA2 in complex with a novel inhibitor
分子名称: N-[4-[(3-cyano-4-naphthalen-2-yloxy-phenyl)sulfamoyl]phenyl]ethanamide, Platelet-activating factor acetylhydrolase, SULFATE ION
著者Liu, Q.F, Xu, Y.C.
登録日2017-09-15
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.876 Å)
主引用文献Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.
J. Med. Chem., 60, 2017
5YE7
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BU of 5ye7 by Molmil
The crystal structure of Lp-PLA2 in complex with a novel inhibitor
分子名称: N-[4-[(4-naphthalen-2-yloxyphenyl)sulfamoyl]phenyl]ethanamide, Platelet-activating factor acetylhydrolase, SULFATE ION
著者Liu, Q.F, Xu, Y.C.
登録日2017-09-15
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.312 Å)
主引用文献Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.
J. Med. Chem., 60, 2017
5YE8
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BU of 5ye8 by Molmil
The crystal structure of Lp-PLA2 in complex with a novel inhibitor
分子名称: N-[3,4-bis(fluoranyl)phenyl]methanesulfonamide, Platelet-activating factor acetylhydrolase
著者Liu, Q.F, Xu, Y.C.
登録日2017-09-15
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.
J. Med. Chem., 60, 2017
5YEA
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BU of 5yea by Molmil
The crystal structure of Lp-PLA2 in complex with a novel inhibitor
分子名称: 4-[[4-[4-chloranyl-3-(trifluoromethyl)phenoxy]-3-cyano-phenyl]sulfamoyl]benzoic acid, Platelet-activating factor acetylhydrolase, SULFATE ION
著者Liu, Q.F, Xu, Y.C.
登録日2017-09-15
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.
J. Med. Chem., 60, 2017
5YYL
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BU of 5yyl by Molmil
Structure of Major Royal Jelly Protein 1 Oligomer
分子名称: (3beta,14beta,17alpha)-ergosta-5,24(28)-dien-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tian, W, Chen, Z.
登録日2017-12-10
公開日2018-08-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Architecture of the native major royal jelly protein 1 oligomer.
Nat Commun, 9, 2018
5X5Y
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BU of 5x5y by Molmil
A membrane protein complex
分子名称: Probable ATP-binding component of ABC transporter, Uncharacterized protein
著者Luo, Q, Yang, X, Huang, Y.
登録日2017-02-18
公開日2017-04-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.465 Å)
主引用文献Structural basis for lipopolysaccharide extraction by ABC transporter LptB2FG
Nat. Struct. Mol. Biol., 24, 2017
7E0F
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BU of 7e0f by Molmil
CryoEM structure of G51D alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Sun, Y.P, Long, H.F, Xia, W.C, Liu, C.
登録日2021-01-27
公開日2021-10-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type alpha-synuclein.
Nat Commun, 12, 2021
7F7H
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BU of 7f7h by Molmil
SARS-CoV-2 S protein RBD in complex with A8-1 Fab
分子名称: Heavy chain of A8-1 Fab, Light chain of A8-1 Fab, Spike glycoprotein S1
著者Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B.
登録日2021-06-29
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献High throughput isolation of potent neutralizing antibodies from convalescent COVID-19 patients.
To Be Published
7YC5
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BU of 7yc5 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from K202.B, bispecific antibody, ...
著者Yoo, Y, Cho, H.S.
登録日2022-06-30
公開日2023-07-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants.
Antiviral Res., 212, 2023
7SEG
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BU of 7seg by Molmil
Crystal structure of the complex of CD16A bound by an anti-CD16A Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Kiefer, J.R, Wallweber, H.A, Polson, A.G.
登録日2021-09-30
公開日2021-11-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.156 Å)
主引用文献A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma.
Leukemia, 36, 2022
4Z1W
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BU of 4z1w by Molmil
CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME mutant D207L Y263F From Synchrotron
分子名称: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome
著者Bhattacharya, S, Satyshur, K.A, Wangkanont, K, Lehtivuori, H, Forest, K.T.
登録日2015-03-27
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015

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件を2024-07-31に公開中

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