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Electron cryo-microscopy of the eukaryotic translation initiation factor 2B from Homo sapiens (updated model of PDB ID: 6CAJ)
分子名称:	2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ...
著者	Tsai, J.C, Miller-Vedam, L.E, Anand, A, Jaishankar, P, Nguyen, H.C, Wang, L, Renslo, A.R, Frost, A, Walter, P.
登録日	2020-12-28
公開日	2021-03-24
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	eIF2B conformation and assembly state regulates the integrated stress response. Elife, 10, 2021

2PVE

NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin
分子名称:	1,2-ETHANEDIOL, ACETATE ION, Rubredoxin, ...
著者	LeMaster, D.M, Anderson, J.S, Wang, L, Guo, Y, Li, H, Hernandez, G.
登録日	2007-05-09
公開日	2007-12-18
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (0.79 Å)
主引用文献	NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin. Bmc Struct.Biol., 7, 2007

2QWQ

Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form
分子名称:	ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者	Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R.
登録日	2007-08-10
公開日	2007-12-18
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (2.21 Å)
主引用文献	Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007

2QWL

Crystal structure of bovine hsc70 (1-394aa)in the ADP state
分子名称:	ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock cognate 71 kDa protein, ...
著者	Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R.
登録日	2007-08-10
公開日	2007-12-18
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007

7E2G

Cryo-EM structure of hDisp1NNN-3C
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1,Protein dispatched homolog 1
著者	Li, W, Wang, L, Gong, X.
登録日	2021-02-05
公開日	2021-12-08
実験手法	ELECTRON MICROSCOPY (3.61 Å)
主引用文献	Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nat Commun, 12, 2021

7E2H

Cryo-EM structure of hDisp1NNN-3C-Cleavage
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1
著者	Li, W, Wang, L, Gong, X.
登録日	2021-02-05
公開日	2021-12-08
実験手法	ELECTRON MICROSCOPY (3.68 Å)
主引用文献	Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nat Commun, 12, 2021

5XM5

Crystal structure of Zinc binding protein ZinT at 1.49 Angstrom from E. coli
分子名称:	Metal-binding protein ZinT, SODIUM ION, ZINC ION
著者	Chen, J, Wang, L, Guo, J, Xu, Y.
登録日	2017-05-12
公開日	2017-05-31
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.493 Å)
主引用文献	Crystal structure of Zinc binding protein ZinT at 1.49 Angstrom from E. coli To Be Published

7E2I

Cryo-EM structure of hDisp1NNN-ShhN
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1, ...
著者	Li, W, Wang, L, Gong, X.
登録日	2021-02-05
公開日	2021-12-08
実験手法	ELECTRON MICROSCOPY (4.07 Å)
主引用文献	Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nat Commun, 12, 2021

5YXC

Crystal structure of Zinc binding protein ZinT in complex with citrate from E. coli
分子名称:	CITRIC ACID, Metal-binding protein ZinT, ZINC ION
著者	Chen, J, Wang, L, Shang, F, Xu, Y.
登録日	2017-12-04
公開日	2017-12-20
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.763 Å)
主引用文献	Crystal structure of E. coli ZinT with one zinc-binding mode and complexed with citrate Biochem. Biophys. Res. Commun., 500, 2018

8JX7

Cryo-EM structure of human ABC transporter ABCC2
分子名称:	ATP-binding cassette sub-family C member 2
著者	Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日	2023-06-30
公開日	2024-01-03
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024

8JY5

Cryo-EM structure of human ABC transporter ABCC2 in apo" state
分子名称:	ATP-binding cassette sub-family C member 2
著者	Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日	2023-07-03
公開日	2024-01-03
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (4.17 Å)
主引用文献	Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024

8JY4

Cryo-EM structure of human ABC transporter ABCC2 in apo' state
分子名称:	ATP-binding cassette sub-family C member 2
著者	Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日	2023-07-02
公開日	2024-01-03
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.58 Å)
主引用文献	Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024

8JXU

Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition
分子名称:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ...
著者	Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日	2023-07-01
公開日	2024-01-03
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.55 Å)
主引用文献	Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024

8JXQ

Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2
分子名称:	2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL
著者	Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日	2023-07-01
公開日	2024-01-03
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.32 Å)
主引用文献	Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024

5Z7H

Crystal structure of CcpE regulatory domain in citrate-bound form from Staphyloccocus aureus
分子名称:	CITRATE ANION, LysR family transcriptional regulator
著者	Chen, J, Wang, L, Shang, F, Xu, Y.
登録日	2018-01-28
公開日	2018-02-28
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Citrate-responsive mechanism of catabolite control protein E from Staphyloccocus aureus To Be Published

5Z72

Crystal structure of CcpC regulatory domain in complex with citrate from Bacillus amyloliquefaciens
分子名称:	CITRATE ANION, CcpC, SODIUM ION
著者	Chen, J, Wang, L, Shang, F, Xu, Y.
登録日	2018-01-26
公開日	2018-02-28
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Mechanistic insights from the crystal structures of a catabolite control protein C on citrate-responsive mechanism To Be Published

7FAT

Structure Determination of the RBD-NB1A7
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nb_1A7
著者	Geng, Y, Shi, Z.Z, Li, X.Y, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C.
登録日	2021-07-07
公開日	2022-05-18
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.99 Å)
主引用文献	Structural basis of nanobodies neutralizing SARS-CoV-2 variants Structure, 30, 2022

7FAU

Structure Determination of the NB1B11-RBD Complex
分子名称:	NB_1B11, Spike protein S1, ZINC ION
著者	Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X.
登録日	2021-07-07
公開日	2022-06-01
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.08 Å)
主引用文献	Structural basis of nanobodies neutralizing SARS-CoV-2 variants. Structure, 30, 2022

7X4E

Structure of 10635-DndE
分子名称:	DNA sulfur modification protein DndE, GLYCEROL
著者	Haiyan, G, Wei, H, Chen, S, Wang, L, Wu, G.
登録日	2022-03-02
公開日	2022-04-20
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.32 Å)
主引用文献	Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635. Mbio, 13, 2022

7XKC

Crystal structure of Daucus Carrot hypoglycemic peptide (DCHP)
分子名称:	DCHP, SULFATE ION
著者	Guo, T, Ren, J.Q, Wang, L, Shi, Y.W, Feng, W.
登録日	2022-04-19
公開日	2022-05-18
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.56 Å)
主引用文献	Characterization of a thermostable, protease-tolerant inhibitor of alpha-glycosidase from carrot: A potential oral additive for treatment of diabetes. Int.J.Biol.Macromol., 209, 2022

7VFB

the complex of SARS-CoV2 3cl and NB2B4
分子名称:	3C-like proteinase, nb2b4
著者	Geng, Y, Sun, Z.C, Wang, L.
登録日	2021-09-11
公開日	2022-03-30
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	An extended conformation of SARS-CoV-2 main protease reveals allosteric targets. Proc.Natl.Acad.Sci.USA, 119, 2022

7VFA

the complex of SARS-CoV2 3CL and NB1A2
分子名称:	3C-like proteinase, NB1A2, SULFATE ION
著者	Sun, Z.C, Wang, L, Geng, Y.
登録日	2021-09-11
公開日	2022-03-30
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	An extended conformation of SARS-CoV-2 main protease reveals allosteric targets. Proc.Natl.Acad.Sci.USA, 119, 2022

7CYE

Cryo-EM structure of sodium-dependent bicarbonate transporter SbtA from Synechocystis sp. PCC 6803
分子名称:	Slr1512 protein
著者	Liu, X.Y, Jiang, Y.L, Wang, L, Hou, W.T, Chen, Y, Zhou, C.Z.
登録日	2020-09-03
公開日	2021-06-23
最終更新日	2024-05-29
実験手法	ELECTRON MICROSCOPY (3.54 Å)
主引用文献	Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB. Cell Discov, 7, 2021

7CYF

Cryo-EM structure of bicarbonate transporter SbtA in complex with PII-like signaling protein SbtB from Synechocystis sp. PCC 6803
分子名称:	ADENOSINE MONOPHOSPHATE, Membrane-associated protein slr1513, SODIUM ION, ...
著者	Liu, X.Y, Jiang, Y.L, Wang, L, Hou, W.T, Chen, Y, Zhou, C.Z.
登録日	2020-09-03
公開日	2021-06-23
最終更新日	2022-02-16
実験手法	ELECTRON MICROSCOPY (3.15 Å)
主引用文献	Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB. Cell Discov, 7, 2021

8HP6

Crystal structure of (S)-2-haloacid dehalogenase D12A mutant
分子名称:	(S)-2-haloacid dehalogenase, SODIUM ION
著者	Yang, Q, Wang, L, Xu, X, Xing, X, Zhou, J.
登録日	2022-12-12
公開日	2023-06-21
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening Catalysis Science And Technology, 2023

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全ヒット件数:	1400
表示件数:	25
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