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7RNV
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BU of 7rnv by Molmil
SH2 domain of guanine nucleotide exchange factor Vav2 in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
7RNU
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BU of 7rnu by Molmil
nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
2O26
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BU of 2o26 by Molmil
Structure of a class III RTK signaling assembly
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor, ...
著者Liu, H, Chen, X, Focia, P.J, He, X.
登録日2006-11-29
公開日2007-03-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
2O27
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BU of 2o27 by Molmil
Structure of a class III RTK signaling assembly
分子名称: Kit ligand
著者Liu, H, Chen, X, Focia, P, He, X.
登録日2006-11-29
公開日2007-03-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
2RFU
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BU of 2rfu by Molmil
Crystal structure of influenza B virus hemagglutinin in complex with LSTc receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza B hemagglutinin (HA), ...
著者Wang, Q, Tian, X, Chen, X, Ma, J.
登録日2007-10-01
公開日2008-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2RFT
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BU of 2rft by Molmil
Crystal structure of influenza B virus hemagglutinin in complex with LSTa receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza B hemagglutinin (HA), ...
著者Wang, Q, Tian, X, Chen, X, Ma, J.
登録日2007-10-01
公開日2008-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E0H
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BU of 2e0h by Molmil
Solution Structure of BmKalphaIT01, an alpha-insect toxin from the Venom of the Chinese Scorpion Buthus martensi Karsch
分子名称: Alpha-neurotoxin TX12
著者Tong, X.T, Chen, X, Wu, H.M.
登録日2006-10-08
公開日2007-10-16
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Solution Structure of BmKalphaIT01, an alpha-Insect Toxin from the Venom of the Chinese Scorpion Buthus martensii Karsch
Biochemistry, 46, 2007
6CIM
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BU of 6cim by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-nicked/intact 12/23RSS complex in Mn2+
分子名称: DNA (5'-D(*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 23RSS substrate forward strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIL
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BU of 6cil by Molmil
PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+
分子名称: High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIK
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BU of 6cik by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+
分子名称: DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 12RSS substrate forward strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6JPJ
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BU of 6jpj by Molmil
Crystal structure of FGF401 in complex of FGFR4
分子名称: Fibroblast growth factor receptor 4, N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide, SULFATE ION
著者Zhou, Z, Chen, X, Chen, Y.
登録日2019-03-27
公開日2019-05-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.638 Å)
主引用文献Characterization of FGF401 as a reversible covalent inhibitor of fibroblast growth factor receptor 4.
Chem.Commun.(Camb.), 55, 2019
6IZJ
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BU of 6izj by Molmil
Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus
分子名称: 1,2-ETHANEDIOL, NITRATE ION, NreA
著者Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J.
登録日2018-12-19
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus.
Biotechnol.Lett., 42, 2020
6K2H
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BU of 6k2h by Molmil
structural characterization of mutated NreA protein in nitrate binding site from staphylococcus aureus.
分子名称: 1,2-ETHANEDIOL, NreA
著者Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J.
登録日2019-05-14
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus.
Biotechnol.Lett., 42, 2020
5GXJ
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BU of 5gxj by Molmil
Zika Virus NS2B-NS3 protease
分子名称: FLAVIVIRUS_NS2B,LINKER,Peptidase S7
著者Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K.
登録日2016-09-18
公開日2017-05-03
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Viral protease activation mechanism
To Be Published
4EXP
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BU of 4exp by Molmil
Structure of mouse Interleukin-34 in complex with mouse FMS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor
著者Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X.
登録日2012-04-30
公開日2012-05-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
3HFH
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BU of 3hfh by Molmil
Crystal structure of tandem FF domains
分子名称: Transcription elongation regulator 1
著者Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X.
登録日2009-05-11
公開日2009-08-18
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150.
J.Mol.Biol., 393, 2009
5KE7
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BU of 5ke7 by Molmil
mouse Klf4 ZnF1-3 and TpG/MpA sequence DNA complex structure
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*AP*CP*CP*TP*C)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
4EXN
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BU of 4exn by Molmil
Crystal structure of mouse Interleukin-34
分子名称: Interleukin-34, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X.
登録日2012-04-30
公開日2012-05-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
5K5I
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BU of 5k5i by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P65
分子名称: DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), SULFATE ION, ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KE6
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BU of 5ke6 by Molmil
mouse Klf4 ZnF1-3 and TpG/CpA sequence DNA complex structure
分子名称: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KEB
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BU of 5keb by Molmil
mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form II
分子名称: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.453 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5H6X
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BU of 5h6x by Molmil
The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila
分子名称: GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION
著者Zhang, N, Chen, X, Gong, X, Ge, H.
登録日2016-11-15
公開日2017-11-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila
Crystals, 8, 2018
3K5K
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BU of 3k5k by Molmil
Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a
分子名称: 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, CHLORIDE ION, Histone-lysine N-methyltransferase, ...
著者Dong, A, Wasney, G.A, Liu, F, Chen, X, Allali-Hassani, A, Senisterra, G, Chau, I, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Frye, S.V, Bochkarev, A, Brown, P.J, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2009-10-07
公開日2009-11-10
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.
J.Med.Chem., 52, 2009
3K6S
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BU of 3k6s by Molmil
Structure of integrin alphaXbeta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-09
公開日2010-01-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
3K72
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BU of 3k72 by Molmil
Structure of integrin alphaX beta2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-11
公開日2010-01-12
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010

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