1D9D
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![BU of 1d9d by Molmil](/molmil-images/mine/1d9d) | CRYSTALL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH SHORT DNA FRAGMENT CARRYING 2'-0-AMINOPROPYL-RNA MODIFICATIONS 5'-D(TCG)-AP(AUC)-3' | 分子名称: | 5'-D(*TP*CP*GP)-R(AP*(U31)P*(C31))-3', DNA POLYMERASE I, MAGNESIUM ION, ... | 著者 | Teplova, M, Wallace, S.T, Tereshko, V, Minasov, G, Simons, A.M, Cook, P.D, Manoharan, M, Egli, M. | 登録日 | 1999-10-27 | 公開日 | 1999-12-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural origins of the exonuclease resistance of a zwitterionic RNA. Proc.Natl.Acad.Sci.USA, 96, 1999
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1COB
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![BU of 1cob by Molmil](/molmil-images/mine/1cob) | CRYSTAL STRUCTURE SOLUTION AND REFINEMENT OF THE SEMISYNTHETIC COBALT SUBSTITUTED BOVINE ERYTHROCYTE ENZYME SUPEROXIDE DISMUTASE AT 2.0 ANGSTROMS RESOLUTION | 分子名称: | COBALT (II) ION, COPPER (II) ION, SUPEROXIDE DISMUTASE | 著者 | Djinovic, K, Coda, A, Antolini, L, Pelosi, G, Desideri, A, Falconi, M, Rotilio, G, Bolognesi, M. | 登録日 | 1992-02-19 | 公開日 | 1993-10-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure solution and refinement of the semisynthetic cobalt-substituted bovine erythrocyte superoxide dismutase at 2.0 A resolution. J.Mol.Biol., 226, 1992
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1CKK
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![BU of 1ckk by Molmil](/molmil-images/mine/1ckk) | CALMODULIN/RAT CA2+/CALMODULIN DEPENDENT PROTEIN KINASE FRAGMENT | 分子名称: | CALCIUM ION, Calcium/calmodulin-dependent protein kinase kinase 1, Calmodulin-1 | 著者 | Osawa, M, Tokumitsu, H, Swindells, M.B, Kurihara, H, Orita, M, Shibanuma, T, Furuya, T, Ikura, M. | 登録日 | 1998-11-20 | 公開日 | 1999-09-10 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase. Nat.Struct.Biol., 6, 1999
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3NG5
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![BU of 3ng5 by Molmil](/molmil-images/mine/3ng5) | Crystal Structure of V30M transthyretin complexed with (-)-epigallocatechin gallate (EGCG) | 分子名称: | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, GLYCEROL, Transthyretin | 著者 | Miyata, M, Nakamura, T, Ikemizu, S, Chirifu, M, Yamagata, Y, Kai, H. | 登録日 | 2010-06-11 | 公開日 | 2010-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site Biochemistry, 2010
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8AX9
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![BU of 8ax9 by Molmil](/molmil-images/mine/8ax9) | |
7LTM
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![BU of 7ltm by Molmil](/molmil-images/mine/7ltm) | Hum8 capsid | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein | 著者 | Mietzsch, M, Agbandje-McKenna, M. | 登録日 | 2021-02-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | Receptor Switching in Newly Evolved Adeno-associated Viruses. J.Virol., 95, 2021
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6N1O
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![BU of 6n1o by Molmil](/molmil-images/mine/6n1o) | |
6ZCI
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![BU of 6zci by Molmil](/molmil-images/mine/6zci) | Crystal structure of BRD4-BD1 in complex with NVS-BET-1 | 分子名称: | (4~{R})-4-(4-chlorophenyl)-1-cyclopropyl-5-(1,5-dimethyl-6-oxidanylidene-pyridin-3-yl)-3-methyl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one, Bromodomain-containing protein 4 | 著者 | Faller, M. | 登録日 | 2020-06-11 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.976 Å) | 主引用文献 | BET bromodomain inhibitors regulate keratinocyte plasticity. Nat.Chem.Biol., 17, 2021
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6YVU
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![BU of 6yvu by Molmil](/molmil-images/mine/6yvu) | Condensin complex from S.cerevisiae ATP-free apo non-engaged state | 分子名称: | Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2,Smc2, ... | 著者 | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Aragon, L, Haering, C.H, Lowe, J. | 登録日 | 2020-04-28 | 公開日 | 2020-07-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nat.Struct.Mol.Biol., 27, 2020
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6TDP
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![BU of 6tdp by Molmil](/molmil-images/mine/6tdp) | Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GL dipeptide in the A pocket. | 分子名称: | Beta-2-microglobulin, GLYCEROL, GLYCINE, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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6TDR
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![BU of 6tdr by Molmil](/molmil-images/mine/6tdr) | Crystal structure of the disulfide engineered HLA-A0201 molecule devoid of peptide (annealed) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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7LMZ
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![BU of 7lmz by Molmil](/molmil-images/mine/7lmz) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LMY
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![BU of 7lmy by Molmil](/molmil-images/mine/7lmy) | Cryo-EM structure of human p97 in complex with NMS-873 in the presence of ATP, Npl4/Ufd1, and Ub6 | 分子名称: | 3-[3-cyclopentylsulfanyl-5-[[3-methyl-4-(4-methylsulfonylphenyl)phenoxy]methyl]-1,2,4-triazol-4-yl]pyridine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN4
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![BU of 7ln4 by Molmil](/molmil-images/mine/7ln4) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN2
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![BU of 7ln2 by Molmil](/molmil-images/mine/7ln2) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN0
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![BU of 7ln0 by Molmil](/molmil-images/mine/7ln0) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN6
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![BU of 7ln6 by Molmil](/molmil-images/mine/7ln6) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN5
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![BU of 7ln5 by Molmil](/molmil-images/mine/7ln5) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 1, Close State) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN1
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![BU of 7ln1 by Molmil](/molmil-images/mine/7ln1) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7LN3
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![BU of 7ln3 by Molmil](/molmil-images/mine/7ln3) | Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2021-02-06 | 公開日 | 2021-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
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7L91
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![BU of 7l91 by Molmil](/molmil-images/mine/7l91) | Structure of Metallo Beta-Lactamase L1 in a Complex with Hydrolyzed Moxalactam Determined by Pink-Beam Serial Crystallography | 分子名称: | (2R)-2-[(R)-carboxy{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}methoxymethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, Putative metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase), ZINC ION | 著者 | Wilamowski, M, Kim, Y, Sherrell, D.A, Lavens, A, Henning, R, Maltseva, N, Endres, M, Babnigg, G, Vukica, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-01-01 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase. Nat Commun, 13, 2022
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6ZGM
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![BU of 6zgm by Molmil](/molmil-images/mine/6zgm) | Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with the thiazolecarboxylate inhibitor ANT2681 | 分子名称: | 5-[[4-(carbamimidamidocarbamoylamino)-3,5-bis(fluoranyl)phenyl]sulfonylamino]-1,3-thiazole-4-carboxylic acid, ACETATE ION, Metallo-beta-lactamase VIM-2-like protein, ... | 著者 | Docquier, J.D, Pozzi, C, Marcoccia, F, De Luca, F, Benvenuti, M, Mangani, S. | 登録日 | 2020-06-19 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | ANT2681: SAR Studies Leading to the Identification of a Metallo-beta-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-ProducingEnterobacteriaceae. Acs Infect Dis., 6, 2020
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8OG5
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![BU of 8og5 by Molmil](/molmil-images/mine/8og5) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 1 | 分子名称: | 1,2-ETHANEDIOL, 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline, ACETATE ION, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OG6
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![BU of 8og6 by Molmil](/molmil-images/mine/8og6) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 1 | 分子名称: | 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline, ACETATE ION, DDB1- and CUL4-associated factor 1 | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OG8
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![BU of 8og8 by Molmil](/molmil-images/mine/8og8) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 3 | 分子名称: | 1,2-ETHANEDIOL, 5-(2-methyl-1-phenyl-propan-2-yl)imidazo[2,1-a]isoquinoline, ACETATE ION, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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