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7WEF
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BU of 7wef by Molmil
SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv289
分子名称: Spike protein S1, The heavy chain of Fab XGv289, The light chain of Fab XGv289
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
7WE9
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BU of 7we9 by Molmil
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, X, Wang, L.
登録日2021-12-23
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
2PL3
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BU of 2pl3 by Molmil
Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ETHANOL, MAGNESIUM ION, ...
著者Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-04-19
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
8PBD
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BU of 8pbd by Molmil
RAD51 filament on dsDNA bound by the BRCA2 c-terminus
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Breast cancer type 2 susceptibility protein, CALCIUM ION, ...
著者Appleby, R, Pellegrini, L.
登録日2023-06-09
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2.
Nat Commun, 14, 2023
8PBC
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BU of 8pbc by Molmil
RAD51 filament on ssDNA bound by the BRCA2 c-terminus
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Breast cancer type 2 susceptibility protein, CALCIUM ION, ...
著者Appleby, R, Pellegrini, L.
登録日2023-06-09
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2.
Nat Commun, 14, 2023
3MAM
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BU of 3mam by Molmil
A molecular switch changes the low to the high affinity state in the substrate binding protein AfProX
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Osmoprotection protein (ProX), ...
著者Tschapek, B, Pittelkow, M, Bremer, E, Schmitt, L, Smits, S.H.
登録日2010-03-24
公開日2011-04-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Arg149 Is Involved in Switching the Low Affinity, Open State of the Binding Protein AfProX into Its High Affinity, Closed State.
J.Mol.Biol., 411, 2011
2OAS
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BU of 2oas by Molmil
Crystal Structure of 4-hydroxybutyrate coenzyme A transferase (AtoA) in complex with CoA from Shewanella oneidensis, Northeast Structural Genomics Target SoR119.
分子名称: 4-hydroxybutyrate coenzyme A transferase, COENZYME A
著者Forouhar, F, Neely, H, Hussain, M, Benach, J, Seetharaman, J, Cunningham, K, Ma, L.C, Owen, L, Fang, Y, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-17
公開日2007-01-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of 4-hydroxybutyrate coenzyme A transferase (AtoA) from Shewanella oneidensis in complex with CoA, Northeast Structural Genomics Target SoR119.
To be Published
2OFG
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BU of 2ofg by Molmil
Solution structure of the n-terminal domain of the zinc(II) ATPase ziaa in its apo form
分子名称: Zinc-transporting ATPase
著者Banci, L, Bertini, I, Ciofi-Baffoni, S, Poggi, L, Robinson, N.J, Vanarotti, M.
登録日2007-01-03
公開日2007-12-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR structural analysis of the soluble domain of ZiaA-ATPase and the basis of selective interactions with copper metallochaperone Atx1.
J.Biol.Inorg.Chem., 15, 2010
8QH9
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BU of 8qh9 by Molmil
X-ray structure of Danio rerio histone deacetylase 6 (HDAC6) CD2 in complex with a S-29b
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Histone deacetylase 6, ...
著者Barinka, C, Motlova, L.
登録日2023-09-07
公開日2024-08-07
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Biological and structural investigation of tetrahydro-beta-carboline-based selective HDAC6 inhibitors with improved stability.
Eur.J.Med.Chem., 276, 2024
1D3C
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BU of 1d3c by Molmil
MICHAELIS COMPLEX OF BACILLUS CIRCULANS STRAIN 251 CYCLODEXTRIN GLYCOSYLTRANSFERASE WITH GAMMA-CYCLODEXTRIN
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, ...
著者Uitdehaag, J.C.M, Kalk, K.H, van der Veen, B.A, Dijkhuizen, L, Dijkstra, B.W.
登録日1999-09-29
公開日1999-12-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The cyclization mechanism of cyclodextrin glycosyltransferase (CGTase) as revealed by a gamma-cyclodextrin-CGTase complex at 1.8-A resolution.
J.Biol.Chem., 274, 1999
2O8S
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BU of 2o8s by Molmil
X-ray Crystal Structure of Protein AGR_C_984 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR120.
分子名称: AGR_C_984p, SULFATE ION
著者Seetharaman, J, Forouhar, F, Su, M, Zhao, L, Cunningham, K, Ma, L.-C, Janjua, H, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-12
公開日2007-01-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Hypothetical Protein AGR_C_984 from Agrobacterium tumefaciens, Northeast Structural Genomics Target AtR120.
To be Published
2O94
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BU of 2o94 by Molmil
The 97H/F mutant Structure of a glutamine-rich domain from histone deacetylase 4
分子名称: Histone deacetylase 4
著者Guo, L, Han, A, Bates, D.L, Chen, L.
登録日2006-12-13
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PK0
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BU of 2pk0 by Molmil
Structure of the S. agalactiae serine/threonine phosphatase at 2.65 resolution
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Rantanen, M.K, Lehtio, L, Rajagopal, L, Rubens, C.E, Goldman, A.
登録日2007-04-17
公開日2007-06-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion
Febs J., 274, 2007
8PYV
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BU of 8pyv by Molmil
Structure of Human PS-1 GSH-analog complex, solved at wavelength 2.755 A
分子名称: L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine, PALMITIC ACID, Prostaglandin E synthase
著者Duman, R, El Omari, K, Mykhaylyk, V, Orr, C, Wagner, A, Vogeley, L, Brown, D.G.
登録日2023-07-26
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8PZ4
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BU of 8pz4 by Molmil
Structure of alginate transporter, AlgE, solved at wavelength 2.755 A
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ...
著者Duman, R, El Omari, K, Mykhaylyk, V, Orr, C, Wagner, A, Vogeley, L, Brown, D.G.
登録日2023-07-26
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8PXG
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BU of 8pxg by Molmil
Structure of Streptactin, solved at wavelength 2.75 A
分子名称: CHLORIDE ION, GLYCEROL, Streptavidin
著者El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Vecchia, L, Jones, E.Y, Wagner, A.
登録日2023-07-23
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
4WZN
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BU of 4wzn by Molmil
CRYSTAL STRUCTURE OF THE 2B PROTEIN SOLUBLE DOMAIN FROM HEPATITIS A VIRUS
分子名称: GLYCEROL, Genome polyprotein
著者Garriga, D, Vives-Adrian, L, Buxaderas, M, Ferreira-da-Silva, F, Almeida, B, Macedo-Ribeiro, S, Pereira, P.J, Verdaguer, N.
登録日2014-11-20
公開日2015-01-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Host Membrane Remodeling Induced by Protein 2B of Hepatitis A Virus.
J.Virol., 89, 2015
2PHW
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BU of 2phw by Molmil
Pterocarpus angolensis lectin (PAL) in complex with Man-9
分子名称: CALCIUM ION, Lectin, MANGANESE (II) ION, ...
著者Garcia-Pino, A, Buts, L, Wyns, L, Imberty, A, Loris, R.
登録日2007-04-12
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How a plant lectin recognizes high mannose oligosaccharides
Plant Physiol., 144, 2007
2PJQ
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BU of 2pjq by Molmil
Crystal structure of Q88U62_LACPL from Lactobacillus plantarum. Northeast Structural Genomics target LpR71
分子名称: Uncharacterized protein lp_2664
著者Benach, J, Su, M, Seetharaman, J, Forouhar, F, Chen, C.X, Cunningham, K, Ma, L.-C, Owens, L, Baran, M, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-04-16
公開日2007-05-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Q88U62_LACPL from Lactobacillus plantarum.
To be Published
8K4F
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BU of 8k4f by Molmil
DHODH in complex with compound A0
分子名称: 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine, 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, ACETATE ION, ...
著者Jian, L, Sun, Q.
登録日2023-07-18
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease.
J.Med.Chem., 66, 2023
2PKW
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BU of 2pkw by Molmil
Crystal structure of UPF0341 protein yhiQ from Salmonella typhimurium, Northeast Structural Genomics Consortium Target StR221
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UPF0341 protein yhiQ
著者Forouhar, F, Su, M, Seetharaman, J, Fang, Y, Xiao, R, Cunningham, K, Ma, L.-C, Owens, L, Liu, J, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-04-18
公開日2007-05-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of UPF0341 protein yhiQ from Salmonella typhimurium.
To be Published
8KAJ
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BU of 8kaj by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*TP*TP*TP*AP*TP*CP*CP*AP*TP*AP*AP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAI
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BU of 8kai by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 17nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
6GNL
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BU of 6gnl by Molmil
Zr(IV)-substituted Keggin directly binding to the side chain of Hen Egg-White Lysozyme (HEWL)
分子名称: CHLORIDE ION, Lysozyme C, ZIRCONIUM(IV) PHOSPHOTUNGSTATE KEGGIN
著者Vandebroek, L, Van Meervelt, L, Parac-Vogt, T.N.
登録日2018-05-31
公開日2018-10-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Direct observation of the ZrIVinteraction with the carboxamide bond in a noncovalent complex between Hen Egg White Lysozyme and a Zr-substituted Keggin polyoxometalate.
Acta Crystallogr C Struct Chem, 74, 2018
8KAM
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BU of 8kam by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.91 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024

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