8QH9
X-ray structure of Danio rerio histone deacetylase 6 (HDAC6) CD2 in complex with a S-29b
Summary for 8QH9
Entry DOI | 10.2210/pdb8qh9/pdb |
Descriptor | Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (8 entities in total) |
Functional Keywords | protein deacetylase, histone deacetylase 6, zinc binding group, inhibitor, danio rerio, hydrolase |
Biological source | Danio rerio (zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 40874.68 |
Authors | |
Primary citation | Scheuerer, S.,Motlova, L.,Schaker-Hubner, L.,Sellmer, A.,Feller, F.,Ertl, F.J.,Koch, P.,Hansen, F.K.,Barinka, C.,Mahboobi, S. Biological and structural investigation of tetrahydro-beta-carboline-based selective HDAC6 inhibitors with improved stability. Eur.J.Med.Chem., 276:116676-116676, 2024 Cited by PubMed: 39067437DOI: 10.1016/j.ejmech.2024.116676 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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