5B03
 
 | | Structure of MoeN5-Sso7d fusion protein in complex with geranyl pyrophosphate | | 分子名称: | GERANYL DIPHOSPHATE, MoeN5,DNA-binding protein 7d | | 著者 | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O. | | 登録日 | 2015-10-27 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5B00
 | | Structure of the prenyltransferase MoeN5 in complex with geranyl pyrophosphate | | 分子名称: | GERANYL DIPHOSPHATE, MoeN5 | | 著者 | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2015-10-27 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
5B0L
 | | Structure of MoeN5-Sso7d fusion protein in complex with beta-nonyl glucoside | | 分子名称: | MoeN5,DNA-binding protein 7d, nonyl beta-D-glucopyranoside | | 著者 | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O. | | 登録日 | 2015-11-02 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
4NFO
 | | Crystal Structure Analysis of the 16mer GCAGACUUAAGUCUGC | | 分子名称: | GCAGACUUAAGUCUGC, SPERMINE | | 著者 | Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. | | 登録日 | 2013-10-31 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA.
Acs Chem.Biol., 9, 2014
|
|
4NFP
 | | Crystal Structure Analysis of the 16mer GCAGNCUUAAGUCUGC containing 8-aza-7-deaza-7-ethynyl Adenosine | | 分子名称: | FORMAMIDE, GCAG(A7E)CUUAAGUCUGC | | 著者 | Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. | | 登録日 | 2013-10-31 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA.
Acs Chem.Biol., 9, 2014
|
|
4NFQ
 | | Crystal Structure Analysis of the 16mer GCAGNCUUAAGUCUGC containing 7-triazolyl-8-aza-7-deazaadenosine | | 分子名称: | GCAG(7AT)CUUAAGUCUGC | | 著者 | Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. | | 登録日 | 2013-10-31 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA.
Acs Chem.Biol., 9, 2014
|
|
7DVJ
 | |
7DV7
 | |
8GVL
 | | PTPN21 FERM | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | | 登録日 | 2022-09-15 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
|
|
8GWH
 | |
8GVV
 | | PTPN21 PTP domain C1108S mutant | | 分子名称: | IODIDE ION, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | | 登録日 | 2022-09-15 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
|
|
8GXE
 | | PTPN21 FERM PTP complex | | 分子名称: | CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | | 登録日 | 2022-09-19 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
|
|
8ITF
 | | Cryo-EM structure of the DMCHA-bound mTAAR9-Gs complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-22 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
8IW4
 | | Cryo-EM structure of the SPE-bound mTAAR9-Gs complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-29 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
8IW9
 | | Cryo-EM structure of the CAD-bound mTAAR9-Gs complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-29 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
8IW7
 | | Cryo-EM structure of the PEA-bound mTAAR9-Gs complex | | 分子名称: | 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-29 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
8IWM
 | | Cryo-EM structure of the PEA-bound mTAAR9 complex | | 分子名称: | 2-PHENYLETHYLAMINE, Trace amine-associated receptor 9 | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-30 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
8IWE
 | | Cryo-EM structure of the SPE-mTAAR9 complex | | 分子名称: | SPERMIDINE, Trace amine-associated receptor 9 | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-29 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
8IW1
 | | Cryo-EM structure of the PEA-bound mTAAR9-Golf complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(olf) subunit alpha, ... | | 著者 | Sun, J.P, Li, Q, Yang, F, Xu, Y.F, Guo, L.L, Lian, S, Zhang, M.H, Rong, N.K. | | 登録日 | 2023-03-29 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature, 618, 2023
|
|
7CBZ
 | | Crystal structure of T2R-TTL-A31 complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-[2-[4-(2-cyclopropylethanoyl)piperazin-1-yl]ethoxy]phenyl]pyridin-2-yl]-N-(phenylmethyl)ethanamide, CALCIUM ION, ... | | 著者 | Yang, J.H, Yan, W. | | 登録日 | 2020-06-15 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.
J.Med.Chem., 64, 2021
|
|
8I30
 | | Crystal structure of the SARS-CoV-2 main protease in complex with 32j | | 分子名称: | (2~{R})-1-[4,4-bis(fluoranyl)cyclohexyl]carbonyl-4,4-bis(fluoranyl)-~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl]pyrrolidine-2-carboxamide, 3C-like proteinase nsp5, CHLORIDE ION | | 著者 | Zeng, R, Huang, C, Xie, L.W, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | | 登録日 | 2023-01-16 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery and structure-activity relationship studies of novel alpha-ketoamide derivatives targeting the SARS-CoV-2 main protease.
Eur.J.Med.Chem., 259, 2023
|
|
7CHF
 | |
7CHH
 | | Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-368-2 Fab heavy chain, ... | | 著者 | Xiao, J, Zhu, Q, Wang, G. | | 登録日 | 2020-07-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2020-11-25 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
|
|
7CHE
 | |
7CH4
 | |
