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6BIY
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BU of 6biy by Molmil
HLA-DRB1 in complex with Histone 2B peptide
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II DR-beta (HLA-DR B), ...
著者Ting, Y.T, Scally, S.W, Rossjohn, J.
登録日2017-11-03
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.050049 Å)
主引用文献The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BIR
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BU of 6bir by Molmil
HLA-DRB1 in complex with citrullinated Vimentin peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Ting, Y.T, Scally, S.W, Rossjohn, J.
登録日2017-11-02
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6BMK
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BU of 6bmk by Molmil
Crystal structure of MHC-I like protein
分子名称: (2R)-1-(decanoyloxy)-3-(phosphonooxy)propan-2-yl octadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Khandokar, Y.B, Le Nours, J, Rossjohn, J.
登録日2017-11-15
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BIN
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BU of 6bin by Molmil
HLA-DRB1 in complex with Type II collagen peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ...
著者Ting, Y.T, Scally, S.W, Rossjohn, J.
登録日2017-11-02
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.50000834 Å)
主引用文献The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
3X13
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BU of 3x13 by Molmil
Crystal structure of HLA-B*0801.N80I
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2014-10-24
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
6BMH
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BU of 6bmh by Molmil
Crystal structure of MHC-I like protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d2, ...
著者Khandokar, Y.B, Le Nours, J, Rossjohn, J.
登録日2017-11-14
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BIZ
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BU of 6biz by Molmil
HLA-DRB1 in complex with citrullinated Histone 2B peptide
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II DR-beta (HLA-DR B), ...
著者Ting, Y.T, Scally, S.W, Rossjohn, J.
登録日2017-11-03
公開日2018-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
J. Biol. Chem., 293, 2018
6CUG
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BU of 6cug by Molmil
Crystal structure of BC8B TCR-CD1b-PC complex
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Shahine, A.E, Rossjohn, J.
登録日2018-03-26
公開日2019-01-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10, 2019
6CUH
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BU of 6cuh by Molmil
Crystal structure of the unliganded BC8B TCR
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Shahine, A.E, Rossjohn, J.
登録日2018-03-26
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10, 2019
6D64
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BU of 6d64 by Molmil
Crystal Structure of Human CD1b in Complex with POPC
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-ETHANEDIOL, Beta-2-microglobulin, ...
著者Shahine, A.E, Rossjohn, J.
登録日2018-04-20
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10, 2019
3X11
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BU of 3x11 by Molmil
Crystal structure of HLA-B*57:01.I80N.L82R.R83G
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2014-10-24
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
3X12
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BU of 3x12 by Molmil
Crystal structure of HLA-B*57:01.I80N
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2014-10-24
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
3X14
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BU of 3x14 by Molmil
Crystal structure of HLA-B*0801.N80I.R82L.G83R
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2014-10-25
公開日2014-12-24
最終更新日2015-04-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
4OZH
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BU of 4ozh by Molmil
S16 protein complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Gliadin-alpha2 peptide, ...
著者Petersen, J, Reid, H.H, Rossjohn, J.
登録日2014-02-16
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Nat.Struct.Mol.Biol., 21, 2014
4OZF
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BU of 4ozf by Molmil
JR5.1 protein complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ...
著者Petersen, J, Reid, H.H, Rossjohn, J.
登録日2014-02-15
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Nat.Struct.Mol.Biol., 21, 2014
4OZI
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BU of 4ozi by Molmil
S2 protein complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HLA class II histocompatibility antigen, ...
著者Petersen, J, Reid, H.H, Rossjohn, J.
登録日2014-02-16
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Nat.Struct.Mol.Biol., 21, 2014
2OGV
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BU of 2ogv by Molmil
Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain
分子名称: Macrophage colony-stimulating factor 1 receptor precursor
著者Walter, M, Lucet, I.S, Patel, O, Broughton, S.E, Bamert, R, Williams, N.K, Fantino, E, Wilks, A.F, Rossjohn, J.
登録日2007-01-09
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.
J.Mol.Biol., 367, 2007
2P4M
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BU of 2p4m by Molmil
High pH structure of Rtms5 H146S variant
分子名称: GFP-like non-fluorescent chromoprotein, IODIDE ION
著者Battad, J.M, Wilmann, P.G, Olsen, S, Byres, E, Smith, S.C, Dove, S.G, Turcic, K.N, Devenish, R.J, Rossjohn, J, Prescott, M.
登録日2007-03-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins
J.Mol.Biol., 368, 2007
4OZG
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BU of 4ozg by Molmil
D2 protein complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Petersen, J, Reid, H.H, Rossjohn, J.
登録日2014-02-16
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Nat.Struct.Mol.Biol., 21, 2014
3P4O
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BU of 3p4o by Molmil
Crystal Structure of H2-Kb in complex with the mutant NP205-LCMV-V3A epitope YTAKYPNL, an 8-mer modified peptide from the LCMV
分子名称: ACETYL GROUP, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Gras, S, Guillonneau, C, Rossjohn, J.
登録日2010-10-06
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of H2-Kb in complex with the mutant NP205-LCMV-V3A epitope YTAKYPNL, an 8-mer modified peptide from the LCMV
To be Published
7KRI
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BU of 7kri by Molmil
FR6-bound SARS-CoV-2 Nsp9 RNA-replicase
分子名称: 1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione, MALONATE ION, Non-structural protein 9, ...
著者Littler, D.R, Gully, B.S, Rossjohn, J.
登録日2020-11-20
公開日2021-07-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9.
J.Biol.Chem., 297, 2021
6BNL
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BU of 6bnl by Molmil
Crystal structure of TCR-MHC-like molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Le Nours, J, Rossjohn, J.
登録日2017-11-16
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Cell Chem Biol, 25, 2018
3CPL
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BU of 3cpl by Molmil
Crystal Structure of H-2Db in complex with a variant M6A of the NP366 peptide from influenza A virus
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Kedzierska, K, Guillonneau, C, Hatton, L.A, Stockwell, D, Gras, S, Webby, R, Rossjohn, J, Purcell, A.W, Doherty, P.C, Turner, S.J.
登録日2008-03-31
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy.
Proc.Natl.Acad.Sci.USA, 105, 2008
6BNK
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BU of 6bnk by Molmil
Crystal structure of TCR-MHC-like molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Le Nours, J, Rossjohn, J.
登録日2017-11-16
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Cell Chem Biol, 25, 2018
3FTG
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BU of 3ftg by Molmil
Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Gras, S, Guillonneau, C, Rossjohn, J.
登録日2009-01-12
公開日2009-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Plos Pathog., 6, 2010

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件を2024-06-12に公開中

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