6BIN
HLA-DRB1 in complex with Type II collagen peptide
Summary for 6BIN
Entry DOI | 10.2210/pdb6bin/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, Type II Collagen 1240Cit 1237-1249, HLA class II histocompatibility antigen, DRB1-4 beta chain, ... (6 entities in total) |
Functional Keywords | hla, mhc, citrulline, rheumatoid arthritis, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 47449.62 |
Authors | Ting, Y.T.,Scally, S.W.,Rossjohn, J. (deposition date: 2017-11-02, release date: 2018-01-17, Last modification date: 2023-11-15) |
Primary citation | Ting, Y.T.,Petersen, J.,Ramarathinam, S.H.,Scally, S.W.,Loh, K.L.,Thomas, R.,Suri, A.,Baker, D.G.,Purcell, A.W.,Reid, H.H.,Rossjohn, J. The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. J. Biol. Chem., 293:3236-3251, 2018 Cited by PubMed: 29317506DOI: 10.1074/jbc.RA117.001013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.50000845062 Å) |
Structure validation
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