6BIN

HLA-DRB1 in complex with Type II collagen peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HLA class II histocompatibility antigen, DR alpha chain	polymer	189	21919.6	1	UniProt (P01903) Pfam (PF00993) Pfam (PF07654)	Homo sapiens (Human)	MHC class II antigen DRA
2	B (C)	Type II Collagen 1240Cit 1237-1249	polymer	13	1438.6	1	UniProt (by SIFTS) (P02458)	Homo sapiens
3	C (B)	HLA class II histocompatibility antigen, DRB1-4 beta chain	polymer	200	23224.6	1	UniProt (P13760) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911)	Homo sapiens (Human)	MHC class II antigen DRB1*4,DR4
4	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	E, F (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	G, H, I (A, C, B)	water	water		18.0	113	Chemie (HOH)

Sequence modifications

A: 5 - 181 (UniProt: P01903)

PDB	External Database	Details
Ile 1	-	expression tag
Lys 2	-	expression tag
Glu 3	-	expression tag
Glu 4	-	expression tag
Thr 182	-	expression tag
Ser 183	-	expression tag
Gly 184	-	expression tag
Asp 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Lys 189	-	expression tag

B: 1 - 190 (UniProt: P13760)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Thr 191	-	expression tag
Gly 192	-	expression tag
Gly 193	-	expression tag
Asp 194	-	expression tag
Asp 195	-	expression tag
Asp 196	-	expression tag
Asp 197	-	expression tag
Lys 198	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	46582.8
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	47449.6

*Water molecules are not included.