5NUF
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![BU of 5nuf by Molmil](/molmil-images/mine/5nuf) | Cytosolic Malate Dehydrogenase 1 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Young, D, Messens, J, Huang, J, Reichheld, J.-P. | 登録日 | 2017-04-29 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
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1XYL
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![BU of 1xyl by Molmil](/molmil-images/mine/1xyl) | THE ROLE OF THE DIVALENT METAL ION IN SUGAR BINDING, RING OPENING, AND ISOMERIZATION BY D-XYLOSE ISOMERASE: REPLACEMENT OF A CATALYTIC METAL BY AN AMINO-ACID | 分子名称: | HYDROXIDE ION, MAGNESIUM ION, XYLOSE ISOMERASE | 著者 | Allen, K.N, Lavie, A, Petsko, G.A, Ringe, D. | 登録日 | 1993-12-07 | 公開日 | 1994-05-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: replacement of a catalytic metal by an amino acid. Biochemistry, 33, 1994
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6FMC
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![BU of 6fmc by Molmil](/molmil-images/mine/6fmc) | Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure | 分子名称: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 | 著者 | Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. | 登録日 | 2018-01-30 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
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1XYC
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![BU of 1xyc by Molmil](/molmil-images/mine/1xyc) | X-RAY CRYSTALLOGRAPHIC STRUCTURES OF D-XYLOSE ISOMERASE-SUBSTRATE COMPLEXES POSITION THE SUBSTRATE AND PROVIDE EVIDENCE FOR METAL MOVEMENT DURING CATALYSIS | 分子名称: | 3-O-METHYLFRUCTOSE IN LINEAR FORM, MAGNESIUM ION, XYLOSE ISOMERASE | 著者 | Lavie, A, Allen, K.N, Petsko, G.A, Ringe, D. | 登録日 | 1994-01-03 | 公開日 | 1994-05-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis. Biochemistry, 33, 1994
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1HCZ
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![BU of 1hcz by Molmil](/molmil-images/mine/1hcz) | LUMEN-SIDE DOMAIN OF REDUCED CYTOCHROME F AT-35 DEGREES CELSIUS | 分子名称: | CYTOCHROME F, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Martinez, S.E, Huang, D, Szczepaniak, A, Cramer, W.A, Smith, J.L. | 登録日 | 1996-09-18 | 公開日 | 1997-03-12 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | The heme redox center of chloroplast cytochrome f is linked to a buried five-water chain. Protein Sci., 5, 1996
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3B3J
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![BU of 3b3j by Molmil](/molmil-images/mine/3b3j) | The 2.55 A crystal structure of the apo catalytic domain of coactivator-associated arginine methyl transferase I(CARM1:28-507, residues 28-146 and 479-507 not ordered) | 分子名称: | BENZAMIDINE, Histone-arginine methyltransferase CARM1 | 著者 | Troffer-Charlier, N, Cura, V, Hassenboehler, P, Moras, D, Cavarelli, J. | 登録日 | 2007-10-22 | 公開日 | 2007-11-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains. Embo J., 26, 2007
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3UPA
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![BU of 3upa by Molmil](/molmil-images/mine/3upa) | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | 分子名称: | kappa light chain variable domain | 著者 | Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. | 登録日 | 2011-11-17 | 公開日 | 2012-06-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
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1XYB
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![BU of 1xyb by Molmil](/molmil-images/mine/1xyb) | X-RAY CRYSTALLOGRAPHIC STRUCTURES OF D-XYLOSE ISOMERASE-SUBSTRATE COMPLEXES POSITION THE SUBSTRATE AND PROVIDE EVIDENCE FOR METAL MOVEMENT DURING CATALYSIS | 分子名称: | D-glucose, MAGNESIUM ION, XYLOSE ISOMERASE | 著者 | Lavie, A, Allen, K.N, Petsko, G.A, Ringe, D. | 登録日 | 1994-01-03 | 公開日 | 1994-05-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis. Biochemistry, 33, 1994
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1H66
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![BU of 1h66 by Molmil](/molmil-images/mine/1h66) | CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,5-diaziridinyl-3-hydroxyl-6-methyl-1,4-benzoquinone | 分子名称: | 2,5-DIAZIRIDIN-1-YL-3-(HYDROXYMETHYL)-6-METHYLCYCLOHEXA-2,5-DIENE-1,4-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | 著者 | Faig, M, Bianchet, M.A, Winski, S, Ross, D, Amzel, L.M. | 登録日 | 2001-06-06 | 公開日 | 2001-09-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones Structure, 9, 2001
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5NU5
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![BU of 5nu5 by Molmil](/molmil-images/mine/5nu5) | |
5NUE
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![BU of 5nue by Molmil](/molmil-images/mine/5nue) | Cytosolic Malate Dehydrogenase 1 (peroxide-treated) | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-ETHOXYETHANOL, ... | 著者 | Young, D, Messens, J, Huang, J, Reichheld, J.-P. | 登録日 | 2017-04-29 | 公開日 | 2018-02-28 | 最終更新日 | 2018-07-04 | 実験手法 | X-RAY DIFFRACTION (1.35000277 Å) | 主引用文献 | Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
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5O7M
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![BU of 5o7m by Molmil](/molmil-images/mine/5o7m) | Single-shot pink beam serial crystallography: Phycocyanin (One chip, chip_1) | 分子名称: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN | 著者 | Meents, A, Oberthuer, D, Lieske, J, Srajer, V, Sarrou, I. | 登録日 | 2017-06-09 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Pink-beam serial crystallography. Nat Commun, 8, 2017
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1H41
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![BU of 1h41 by Molmil](/molmil-images/mine/1h41) | Pseudomonas cellulosa E292A alpha-D-glucuronidase mutant complexed with aldotriuronic acid | 分子名称: | 1,2-ETHANEDIOL, 4-O-methyl-alpha-D-glucopyranuronic acid, ALPHA-GLUCURONIDASE, ... | 著者 | Nurizzo, D, Nagy, T, Gilbert, H.J, Davies, G.J. | 登録日 | 2002-09-25 | 公開日 | 2003-05-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Alpha-Glucuronidase,Glca67A,of Cellvibrio Japonicus Utilizes the Carboxylate and Methyl Groups of Aldobiouronic Acid as Important Substrate Recognition Determinants J.Biol.Chem., 278, 2003
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3BXS
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![BU of 3bxs by Molmil](/molmil-images/mine/3bxs) | Crystal Structures Of Highly Constrained Substrate And Hydrolysis Products Bound To HIV-1 Protease. Implications For Catalytic Mechanism | 分子名称: | (9S,12S)-9-(1-methylethyl)-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid, Protease, SULFATE ION | 著者 | Tyndall, J.D, Pattenden, L.K, Reid, R.C, Hu, S.H, Alewood, D, Alewood, P.F, Walsh, T, Fairlie, D.P, Martin, J.L. | 登録日 | 2008-01-14 | 公開日 | 2008-03-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structures of Highly Constrained Substrate and Hydrolysis Products Bound to HIV-1 Protease. Implications for the Catalytic Mechanism Biochemistry, 47, 2008
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1PZ2
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![BU of 1pz2 by Molmil](/molmil-images/mine/1pz2) | Crystal structure of a transient covalent reaction intermediate of a family 51 alpha-L-arabinofuranosidase | 分子名称: | Alpha-L-arabinofuranosidase, alpha-L-arabinofuranose | 著者 | Hoevel, K, Shallom, D, Niefind, K, Belakhov, V, Shoham, G, Baasov, T, Shoham, Y, Schomburg, D. | 登録日 | 2003-07-09 | 公開日 | 2003-10-07 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure and snapshots along the reaction pathway of a family 51 alpha-L-arabinofuranosidase Embo J., 22, 2003
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1H38
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![BU of 1h38 by Molmil](/molmil-images/mine/1h38) | Structure of a T7 RNA polymerase elongation complex at 2.9A resolution | 分子名称: | 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... | 著者 | Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. | 登録日 | 2002-08-24 | 公開日 | 2002-11-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature, 420, 2002
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1HHN
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![BU of 1hhn by Molmil](/molmil-images/mine/1hhn) | Calreticulin P-domain | 分子名称: | CALRETICULIN | 著者 | Ellgaard, L, Riek, R, Herrmann, T, Guntert, P, Braun, D, Helenius, A, Wuthrich, K. | 登録日 | 2000-12-22 | 公開日 | 2001-03-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of the Calreticulin P-Domain Proc.Natl.Acad.Sci.USA, 98, 2001
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3HG0
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![BU of 3hg0 by Molmil](/molmil-images/mine/3hg0) | Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1 | 分子名称: | Baseplate protein, Designed Ankyrin Repeat Protein (DARPin) 20 | 著者 | Veesler, D, Dreier, B, Blangy, S, Lichiere, J, Tremblay, D, Moineau, S, Spinelli, S, Tegoni, M, Pluckthun, A, Campanacci, V, Cambillau, C. | 登録日 | 2009-05-13 | 公開日 | 2009-09-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode. J.Biol.Chem., 284, 2009
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6E71
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![BU of 6e71 by Molmil](/molmil-images/mine/6e71) | Structure of Human Transthyretin Val30Met/Thr119Met Mutant | 分子名称: | DI(HYDROXYETHYL)ETHER, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E78
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![BU of 6e78 by Molmil](/molmil-images/mine/6e78) | Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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5KZN
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![BU of 5kzn by Molmil](/molmil-images/mine/5kzn) | Metabotropic Glutamate Receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Metabotropic glutamate receptor 2 | 著者 | Chappell, M.D, Li, R, Smith, S.C, Dressman, B.A, Tromiczak, E.G, Tripp, A.E, Blanco, M.-J, Vetman, T, Quimby, S.J, Matt, J, Britton, T, Fivush, A.M, Schkeryantz, J.M, Mayhugh, D, Erickson, J.A, Bures, M, Jaramillo, C, Carpintero, M, de Diego, J.E, Barberis, M, Garcia-Cerrada, S, Soriano, J.F, Antonysamy, S, Atwell, S, MacEwan, I, Condon, B, Bradley, C, Wang, J, Zhang, A, Conners, K, Groshong, C, Wasserman, S.R, Koss, J.W, Witkin, J.M, Li, X, Overshiner, C, Wafford, K.A, Seidel, W, Wang, X.-S, Heinz, B.A, Swanson, S, Catlow, J, Bedwell, D, Monn, J.A, Mitch, C.H, Ornstein, P. | 登録日 | 2016-07-25 | 公開日 | 2016-12-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity. J. Med. Chem., 59, 2016
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6EP7
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![BU of 6ep7 by Molmil](/molmil-images/mine/6ep7) | ARABIDOPSIS THALIANA GSTU23, GSH bound | 分子名称: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase U23, ... | 著者 | Tossounian, M.A, Van Molle, I, Wahni, K, Jacques, S, Vertommen, D, Gevaert, K, Van Breusegem, F, Young, D, Rosado, L, Messens, J. | 登録日 | 2017-10-11 | 公開日 | 2018-04-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.947 Å) | 主引用文献 | Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage. Biochim. Biophys. Acta, 1862, 2018
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1HVX
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![BU of 1hvx by Molmil](/molmil-images/mine/1hvx) | BACILLUS STEAROTHERMOPHILUS ALPHA-AMYLASE | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, SODIUM ION | 著者 | Suvd, D, Fujimoto, Z, Takase, K, Matsumura, M, Mizuno, H. | 登録日 | 2001-01-08 | 公開日 | 2001-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Bacillus stearothermophilus alpha-amylase: possible factors determining the thermostability. J.Biochem., 129, 2001
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1LIT
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![BU of 1lit by Molmil](/molmil-images/mine/1lit) | HUMAN LITHOSTATHINE | 分子名称: | LITHOSTATHINE | 著者 | Bertrand, J.A, Pignol, D, Bernard, J.-P, Verdier, J.-M, Dagorn, J.-C, Fontacilla-Camps, J.C. | 登録日 | 1996-01-17 | 公開日 | 1997-01-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation. EMBO J., 15, 1996
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1PUL
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![BU of 1pul by Molmil](/molmil-images/mine/1pul) | Solution structure for the 21KDa caenorhabditis elegans protein CE32E8.3. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET WR33 | 分子名称: | Hypothetical protein C32E8.3 in chromosome I | 著者 | Tejero, R, Aramini, J.M, Swapna, G.V.T, Monleon, D, Chiang, Y, Macapagal, D, Gunsalus, K.C, Kim, S, Szyperski, T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-06-25 | 公開日 | 2005-06-21 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Backbone 1H, 15N and 13C assignments for the 21 kDa Caenorhabditis elegans homologue of "brain-specific" protein. J.Biomol.Nmr, 28, 2004
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