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4LUQ
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BU of 4luq by Molmil
Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3
分子名称: CALCIUM ION, Uncharacterized protein
著者Wang, T, Li, L, Zhang, W.
登録日2013-07-25
公開日2013-09-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Insights on the Bacteriolytic and Self-protection Mechanism of Muramidase Effector Tse3 in Pseudomonas aeruginosa
J.Biol.Chem., 288, 2013
4QY0
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BU of 4qy0 by Molmil
Structure of H10 from human-infecting H10N8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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BU of 4qy2 by Molmil
Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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BU of 4qy1 by Molmil
Structure of H10 from human-infecting H10N8 in complex with avian receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
7VUL
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BU of 7vul by Molmil
Structure of Klebsiella Phage P560 depolymerase
分子名称: Non-contractile tail fiber protein, SULFATE ION
著者Li, M, Chen, R, Zhang, S, Zhang, W.
登録日2021-11-02
公開日2022-11-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure of Klebsiella Phage P560 depolymerase
To Be Published
7L97
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BU of 7l97 by Molmil
Crystal structure of STAMBPL1 in complex with an engineered binder
分子名称: 1,2-ETHANEDIOL, AMSH-like protease, SULFATE ION, ...
著者Guo, Y, Dong, A, Hou, F, Li, Y, Zhang, W, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2021-01-02
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1.
J.Biol.Chem., 297, 2021
6HYN
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BU of 6hyn by Molmil
Structure of ATG13 LIR motif bound to GABARAP
分子名称: Autophagy-related protein 13,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D.
登録日2018-10-22
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
6HOI
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BU of 6hoi by Molmil
Structure of Beclin1 LIR motif bound to GABARAPL1
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beclin-1, ...
著者Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T.
登録日2018-09-17
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
6HYM
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BU of 6hym by Molmil
Structure of PCM1 LIR motif bound to GABARAP
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pericentriolar material 1 protein,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D.
登録日2018-10-22
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
6HOH
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BU of 6hoh by Molmil
Structure of VPS34 LIR motif (S249E) bound to GABARAP
分子名称: Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, TRIETHYLENE GLYCOL
著者Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T.
登録日2018-09-17
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
7U0N
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BU of 7u0n by Molmil
Crystal structure of chimeric omicron RBD (strain BA.1) complexed with human ACE2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Geng, Q, Shi, K, Ye, G, Zhang, W, Aihara, H, Li, F.
登録日2022-02-18
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural Basis for Human Receptor Recognition by SARS-CoV-2 Omicron Variant BA.1.
J.Virol., 96, 2022
7M3Q
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BU of 7m3q by Molmil
Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ...
著者Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S.
登録日2021-03-18
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
To be published
7C0N
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BU of 7c0n by Molmil
Crystal structure of a self-assembling galactosylated peptide homodimer
分子名称: SULFATE ION, Self-assembling galactosylated tyrosine-rich peptide, beta-D-galactopyranose
著者He, C, Wu, S, Chi, C, Zhang, W, Ma, M, Lai, L, Dong, S.
登録日2020-05-01
公開日2020-10-07
最終更新日2020-10-21
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献Glycopeptide Self-Assembly Modulated by Glycan Stereochemistry through Glycan-Aromatic Interactions.
J.Am.Chem.Soc., 142, 2020
7DEB
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BU of 7deb by Molmil
Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck/Eastern China/L0230/2010 (H5N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Sun, H, Sun, H, Song, J, Zhang, W, Qi, J, Gao, G.F, Liu, J.
登録日2020-11-03
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals
To Be Published
7DEA
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BU of 7dea by Molmil
Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck Northern China/22/2017 (H5N6)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Sun, H, Sun, H, Song, J, Zhang, W, Wei, X, Qi, J, Gao, G.F, Liu, J.
登録日2020-11-03
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals
To Be Published
5NS9
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BU of 5ns9 by Molmil
Crystal structure of the GluA2 LBD (L483Y-N754S-L758V) in complex with glutamate
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ...
著者Eibl, C, Plested, A.J.R.
登録日2017-04-25
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Unitary Properties of AMPA Receptors with Reduced Desensitization.
Biophys. J., 113, 2017
2FZN
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BU of 2fzn by Molmil
Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and complexed with proline
分子名称: Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tanner, J.J.
登録日2006-02-09
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hydrogen Bonding Interactions of the 2-OH Ribityl Group and the N(5) Position of the FAD Cofactor Regulate PutA-membrane Associations in Escherichia coli
To be Published
2FZM
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BU of 2fzm by Molmil
Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and complexed with SO2
分子名称: Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tanner, J.J.
登録日2006-02-09
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redox-induced changes in flavin structure and roles of flavin N(5) and the ribityl 2'-OH group in regulating PutA--membrane binding.
Biochemistry, 46, 2007
6FE8
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BU of 6fe8 by Molmil
Cryo-EM structure of the core Centromere Binding Factor 3 complex
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1
著者Zhang, W.J, Lukoynova, N, Miah, S, Vaughan, C.K.
登録日2017-12-30
公開日2018-08-01
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
6GSA
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BU of 6gsa by Molmil
Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10
分子名称: Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Zhang, W.J, Lukoynova, N, Vaughan, C.K.
登録日2018-06-13
公開日2018-08-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
7YV4
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BU of 7yv4 by Molmil
Crystal structure of human UCHL3 in complex with Farrerol
分子名称: (2~{S})-2-(4-hydroxyphenyl)-6,8-dimethyl-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, Ubiquitin carboxyl-terminal hydrolase isozyme L3
著者Mao, Z.Y, Xu, X.J, Zhang, W.T.
登録日2022-08-18
公開日2023-04-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer.
Nat Commun, 14, 2023
3B6T
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BU of 3b6t by Molmil
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
著者Cho, Y, Lolis, E, Howe, J.R.
登録日2007-10-29
公開日2008-02-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
8I71
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BU of 8i71 by Molmil
Hepatitis B virus core protein Y132A mutant in complex with Linvencorvir (RG7907), a Hepatitis B Virus (HBV) Core Protein Allosteric Modulator (CpAM)
分子名称: 3-[(8~{a}~{S})-7-[[5-ethoxycarbonyl-4-(3-fluoranyl-2-methyl-phenyl)-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-3-oxidanylidene-5,6,8,8~{a}-tetrahydro-1~{H}-imidazo[1,5-a]pyrazin-2-yl]-2,2-dimethyl-propanoic acid, CHLORIDE ION, Capsid protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2023-01-30
公開日2023-03-22
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection.
J.Med.Chem., 66, 2023
5V5H
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BU of 5v5h by Molmil
OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.2
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA-directed RNA polymerase L, SODIUM ION, ...
著者Khare, B, Mark, B.L.
登録日2017-03-14
公開日2017-05-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
PLoS Pathog., 13, 2017
5V6A
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BU of 5v6a by Molmil
Crystal structure of the Middle East respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant ME.2
分子名称: CHLORIDE ION, CITRATE ANION, ME.2, ...
著者Bailey-Elkin, B.A, Mark, B.L.
登録日2017-03-16
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
PLoS Pathog., 13, 2017

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